MCM4/YPR019W Literature Guide Help

Other names published for MCM4: HCD21, CDC54, YPR019W

MCM4 - Protein Sequence Features (13)

ReferenceOther Genes Addressed
Bochman ML and Schwacha A  (2010) The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'. Nucleic Acids Res 38(18):6078-88
Randell JC, et al.  (2010) Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7. Mol Cell 40(3):353-63
Sheu YJ and Stillman B  (2010) The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4. Nature 463(7277):113-7
Bochman ML, et al.  (2008) Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability. Mol Cell Biol 28(19):5865-73
Devault A, et al.  (2008) Interplay between S-Cyclin-dependent Kinase and Dbf4-dependent Kinase in Controlling DNA Replication through Phosphorylation of Yeast Mcm4 N-Terminal Domain. Mol Biol Cell 19(5):2267-77
Bochman ML and Schwacha A  (2007) Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step. J Biol Chem 282(46):33795-804
Hoang ML, et al.  (2007) Structural changes in Mcm5 protein bypass Cdc7-Dbf4 function and reduce replication origin efficiency in Saccharomyces cerevisiae. Mol Cell Biol 27(21):7594-602
Moses AM, et al.  (2007) Regulatory evolution in proteins by turnover and lineage-specific changes of cyclin-dependent kinase consensus sites. Proc Natl Acad Sci U S A 104(45):17713-8
Sheu YJ and Stillman B  (2006) Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression. Mol Cell 24(1):101-13
Davey MJ, et al.  (2003) Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture. J Biol Chem 278(7):4491-9
Lei M, et al.  (2002) Two mcm3 mutations affect different steps in the initiation of DNA replication. J Biol Chem 277(34):30824-31
Tye BK and Sawyer S  (2000) The hexameric eukaryotic MCM helicase: building symmetry from nonidentical parts. J Biol Chem 275(45):34833-6
Whitbread LA and Dalton S  (1995) Cdc54 belongs to the Cdc46/Mcm3 family of proteins which are essential for initiation of eukaryotic DNA replication. Gene 155(1):113-7