PRC1/YMR297W Literature Guide Help

Other names published for PRC1: LBC1, CPY, carboxypeptidase C PRC1, YMR297W

PRC1 - Protein Sequence Features (25)

ReferenceOther Genes Addressed
Breidenbach MA, et al.  (2012) Mapping yeast N-glycosites with isotopically recoded glycans. Mol Cell Proteomics 11(6):M111.015339
Izawa T, et al.  (2012) Yos9p and Hrd1p mediate ER retention of misfolded proteins for ER-associated degradation. Mol Biol Cell 23(7):1283-93
Forte GM, et al.  (2011) N-terminal acetylation inhibits protein targeting to the endoplasmic reticulum. PLoS Biol 9(5):e1001073
Kawaguchi S, et al.  (2010) Interplay of substrate retention and export signals in endoplasmic reticulum quality control. PLoS One 5(11):e15532
Spear ED and Ng DT  (2005) Single, context-specific glycans can target misfolded glycoproteins for ER-associated degradation. J Cell Biol 169(1):73-82
Baxter SM, et al.  (2004) Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast. Mol Cell Proteomics 3(3):209-25
Kato M, et al.  (2003) The propeptide in the precursor form of carboxypeptidase Y ensures cooperative unfolding and the carbohydrate moiety exerts a protective effect against heat and pressure. Eur J Biochem 270(22):4587-93
Shimizu H, et al.  (1999) Role of carbohydrate moiety in carboxypeptidase Y: structural study of mutant enzyme lacking carbohydrate moiety. Biosci Biotechnol Biochem 63(6):1045-50
Ramos C and Winther JR  (1996) Exchange of regions of the carboxypeptidase Y propeptide. Sequence specificity and function in folding in vivo. Eur J Biochem 242(1):29-35
Simeon A, et al.  (1995) Vacuolar carboxypeptidase Y of Saccharomyces cerevisiae is glycosylated, sorted and matured in the fission yeast Schizosaccharomyces pombe. Yeast 11(3):271-82
Endrizzi JA, et al.  (1994) 2.8-A structure of yeast serine carboxypeptidase. Biochemistry 33(37):11106-20
Marcusson EG, et al.  (1994) The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene. Cell 77(4):579-86
Mortensen UH and Breddam K  (1994) A conserved glutamic acid bridge in serine carboxypeptidases, belonging to the alpha/beta hydrolase fold, acts as a pH-dependent protein-stabilizing element. Protein Sci 3(5):838-42
Ramos C, et al.  (1994) Requirement of the propeptide for in vivo formation of active yeast carboxypeptidase Y. J Biol Chem 269(9):7006-12
Sorensen SO and Winther JR  (1994) Active-site residues of procarboxypeptidase Y are accessible to chemical modification. Biochim Biophys Acta 1205(2):289-93
Stennicke HR, et al.  (1994) Effects of introduced aspartic and glutamic acid residues on the P'1 substrate specificity, pH dependence and stability of carboxypeptidase Y. Protein Eng 7(7):911-6
Finger A, et al.  (1993) Analysis of two mutated vacuolar proteins reveals a degradation pathway in the endoplasmic reticulum or a related compartment of yeast. Eur J Biochem 218(2):565-74
Mukhtar M, et al.  (1992) The carboxypeptidase Y-encoding gene from Candida albicans and its transcription during yeast-to-hyphae conversion. Gene 121(1):173-7
Bird P, et al.  (1987) Translocation in yeast and mammalian cells: not all signal sequences are functionally equivalent. J Cell Biol 105(6 Pt 2):2905-14
Stevens TH, et al.  (1986) Gene dosage-dependent secretion of yeast vacuolar carboxypeptidase Y. J Cell Biol 102(5):1551-7
Trimble RB, et al.  (1983) GlycoProtein biosynthesis in yeast. protein conformation affects processing of high mannose oligosaccharides on carboxypeptidase Y and invertase. J Biol Chem 258(4):2562-7
Nakagawa Y, et al.  (1982) Carboxypeptidase Y from Saccharomyces cerevisiae. Conformational differences reflected in kinetic behaviour in water and deuterium oxide. Biochim Biophys Acta 706(1):141-3
Hayashi R, et al.  (1975) Evidence for an essential histidine in carboxypeptidase Y. Reaction with the chloromethyl ketone derivative of benzyloxycarbonyl-L-phenylalanine. J Biol Chem 250(13):5221-6
Hayashi R, et al.  (1973) Carboxypeptidase from yeast. Large scale preparation and the application to COOH-terminal analysis of peptides and proteins. J Biol Chem 248(7):2296-302
Hayashi R, et al.  (1973) Serine at the active center of yeast carboxypeptidase. J Biol Chem 248(24):8366-9