CYB2/YML054C Literature Guide Help

Other names published for CYB2: FCB2, YML054C

CYB2 - Protein Sequence Features (22)

ReferenceOther Genes Addressed
Chen ZW, et al.  (2012) High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1, 2, 3-thiadiazole. Implications for inhibitor specificity and drug design. Biochimie 94(5):1172-9
Gallego O, et al.  (2010) A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae. Mol Syst Biol 6():430
Boubacar AK, et al.  (2007) Flavocytochrome b(2): Reactivity of Its Flavin with Molecular Oxygen. Biochemistry 46(45):13080-8
Cenas N, et al.  (2007) Potentiometric and Further Kinetic Characterization of the Flavin-Binding Domain of Saccharomyces cerevisiae Flavocytochrome b(2). Inhibition by Anions Binding in the Active Site. Biochemistry 46(15):4661-70
Sato T, et al.  (2005) Comparison of the protein-unfolding pathways between mitochondrial protein import and atomic-force microscopy measurements. Proc Natl Acad Sci U S A 102(50):17999-8004
Mowat CG, et al.  (2004) Altered substrate specificity in flavocytochrome b2: structural insights into the mechanism of L-lactate dehydrogenation. Biochemistry 43(29):9519-26
Sobrado P and Fitzpatrick PF  (2003) Solvent and primary deuterium isotope effects show that lactate CH and OH bond cleavages are concerted in Y254F flavocytochrome b2, consistent with a hydride transfer mechanism. Biochemistry 42(51):15208-14
Gondry M, et al.  (2001) The catalytic role of tyrosine 254 in flavocytochrome b2 (L-lactate dehydrogenase from baker's yeast). Comparison between the Y254F and Y254L mutant proteins. Eur J Biochem 268(18):4918-27
Mowat CG, et al.  (2000) Kinetic and crystallographic studies on the active site Arg289Lys mutant of flavocytochrome b2 (yeast L-lactate dehydrogenase). Biochemistry 39(12):3266-75
Chen X, et al.  (1999) Signal peptides having standard and nonstandard cleavage sites can be processed by Imp1p of the mitochondrial inner membrane protease. J Biol Chem 274(53):37750-4
Matouschek A, et al.  (1997) Active unfolding of precursor proteins during mitochondrial protein import. EMBO J 16(22):6727-36
Gartner F, et al.  (1995) The sorting signal of cytochrome b2 promotes early divergence from the general mitochondrial import pathway and restricts the unfoldase activity of matrix Hsp70. EMBO J 14(23):6043-57
Gruhler A, et al.  (1995) A novel intermediate on the import pathway of cytochrome b2 into mitochondria: evidence for conservative sorting. EMBO J 14(7):1349-59
Lederer F  (1994) The cytochrome b5-fold: an adaptable module. Biochimie 76(7):674-92
Glick BS, et al.  (1993) Import of cytochrome b2 to the mitochondrial intermembrane space: the tightly folded heme-binding domain makes import dependent upon matrix ATP. Protein Sci 2(11):1901-17
Schwarz E, et al.  (1993) Targeting of cytochrome b2 into the mitochondrial intermembrane space: specific recognition of the sorting signal. EMBO J 12(6):2295-302
Lodi T and Guiard B  (1991) Complex transcriptional regulation of the Saccharomyces cerevisiae CYB2 gene encoding cytochrome b2: CYP1(HAP1) activator binds to the CYB2 upstream activation site UAS1-B2. Mol Cell Biol 11(7):3762-72
Haumont PY, et al.  (1987) Amino-acid sequence of the cytochrome-b5-like heme-binding domain from Hansenula anomala flavocytochrome b2. Eur J Biochem 169(3):539-46
Guiard B  (1985) Structure, expression and regulation of a nuclear gene encoding a mitochondrial protein: the yeast L(+)-lactate cytochrome c oxidoreductase (cytochrome b2). EMBO J 4(12):3265-72
Ghrir R, et al.  (1984) Primary structure of flavocytochrome b2 from baker's yeast. Purification by reverse-phase high-pressure liquid chromatography and sequencing of fragment alpha cyanogen bromide peptides. Eur J Biochem 139(1):59-74
Guiard B and Lederer F  (1977) The "b5-like" domain from chicken-liver sulfite oxidase: a new case of common ancestral origin with liver cytochrome b5 and bakers' yeast cytochrome b2 core. Eur J Biochem 74(1):181-90
Prats M  (1977) Proteolysis of L-(+)-lactate cytochrome c oxidoreductase (cytochrome b2) extracted from Saccharomyces cerevisiae and Hansenula anomala yeasts. Eur J Biochem 75(2):619-25