ERG6/YML008C Literature Guide Help

Other names published for ERG6: ISE1, LIS1, SED6, VID1, sterol 24-C-methyltransferase, YML008C

ERG6 - Protein Sequence Features (11)

ReferenceOther Genes Addressed
Wlodarski T, et al.  (2011) Comprehensive Structural and Substrate Specificity Classification of the Saccharomyces cerevisiae Methyltransferome. PLoS One 6(8):e23168
Petrossian TC and Clarke SG  (2009) Multiple Motif Scanning to identify methyltransferases from the yeast proteome. Mol Cell Proteomics 8(7):1516-26
Ganapathy K, et al.  (2008) Molecular probing of the Saccharomyces cerevisiae sterol 24-C methyltransferase reveals multiple amino acid residues involved with C(2)-transfer activity. Biochim Biophys Acta 1781(6-7):344-51
Jayasimha P and Nes WD  (2008) Photoaffinity Labeling and Mutational Analysis of 24-C-Sterol Methyltransferase Defines the AdoMet Binding Site. Lipids 43(8):681-93
Nes WD, et al.  (2008) Yeast sterol C24-methyltransferase: role of highly conserved tyrosine-81 in catalytic competence studied by site-directed mutagenesis and thermodynamic analysis. Arch Biochem Biophys 477(2):313-23
Mullner H, et al.  (2004) Targeting of proteins involved in sterol biosynthesis to lipid particles of the yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1663(1-2):9-13
Nes WD, et al.  (2004) Sterol methyltransferase: functional analysis of highly conserved residues by site-directed mutagenesis. Biochemistry 43(2):569-76
Nes WD, et al.  (2002) Active site mapping and substrate channeling in the sterol methyltransferase pathway. J Biol Chem 277(45):42549-56
Niewmierzycka A and Clarke S  (1999) S-Adenosylmethionine-dependent methylation in Saccharomyces cerevisiae. Identification of a novel protein arginine methyltransferase. J Biol Chem 274(2):814-24
Nes WD, et al.  (1998) Overexpression, purification, and stereochemical studies of the recombinant (S)-adenosyl-L-methionine: delta 24(25)- to delta 24(28)-sterol methyl transferase enzyme from Saccharomyces cerevisiae. Arch Biochem Biophys 353(2):297-311
Hardwick KG and Pelham HR  (1994) SED6 is identical to ERG6, and encodes a putative methyltransferase required for ergosterol synthesis. Yeast 10(2):265-9