TOR1/YJR066W Literature Guide Help

Other names published for TOR1: DRR1, YJR066W

TOR1 - Protein Sequence Features (24)

ReferenceOther Genes Addressed
Takahara T and Maeda T  (2012) Transient sequestration of TORC1 into stress granules during heat stress. Mol Cell 47(2):242-52
Yan G, et al.  (2012) The TOR Complex 1 Is a Direct Target of Rho1 GTPase. Mol Cell 45(6):743-53
Hardt M, et al.  (2011) Activating mutations of TOR (target of rapamycin). Genes Cells 16(2):141-51
Dames SA  (2010) Structural Basis for the Association of the Redox-sensitive Target of Rapamycin FATC Domain with Membrane-mimetic Micelles. J Biol Chem 285(10):7766-75
Knutson BA  (2010) Insights into the domain and repeat architecture of target of rapamycin. J Struct Biol 170(2):354-63
Shertz CA, et al.  (2010) Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom. BMC Genomics 11():510
Puria R, et al.  (2008) Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 105(20):7194-9
Adami A, et al.  (2007) Structure of TOR and its complex with KOG1. Mol Cell 27(3):509-16
Li H, et al.  (2006) Nutrient regulates Tor1 nuclear localization and association with rDNA promoter. Nature 442(7106):1058-61
Reinke A, et al.  (2006) Caffeine Targets TOR Complex I and Provides Evidence for a Regulatory Link between the FRB and Kinase Domains of Tor1p. J Biol Chem 281(42):31616-26
Dames SA, et al.  (2005) The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability. J Biol Chem 280(21):20558-64
Xie MW, et al.  (2005) Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A 102(20):7215-20
Ai W, et al.  (2002) Regulation of subtelomeric silencing during stress response. Mol Cell 10(6):1295-305
Bertram PG, et al.  (2000) Tripartite regulation of Gln3p by TOR, Ure2p, and phosphatases. J Biol Chem 275(46):35727-33
Kunz J, et al.  (2000) HEAT repeats mediate plasma membrane localization of Tor2p in yeast. J Biol Chem 275(47):37011-20
Alarcon CM, et al.  (1999) Protein kinase activity and identification of a toxic effector domain of the target of rapamycin TOR proteins in yeast. Mol Biol Cell 10(8):2531-46
Zheng XF and Schreiber SL  (1997) Target of rapamycin proteins and their kinase activities are required for meiosis. Proc Natl Acad Sci U S A 94(7):3070-5
Freeman K and Livi GP  (1996) Missense mutations at the FKBP12-rapamycin-binding site of TOR1. Gene 172(1):143-7
Lorenz MC and Heitman J  (1995) TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin. J Biol Chem 270(46):27531-7
Zheng XF, et al.  (1995) TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin. Cell 82(1):121-30
Cafferkey R, et al.  (1994) Yeast TOR (DRR) proteins: amino-acid sequence alignment and identification of structural motifs. Gene 141(1):133-6
Helliwell SB, et al.  (1994) TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast. Mol Biol Cell 5(1):105-18
Stan R, et al.  (1994) Interaction between FKBP12-rapamycin and TOR involves a conserved serine residue. J Biol Chem 269(51):32027-30
Cafferkey R, et al.  (1993) Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity. Mol Cell Biol 13(10):6012-23