KAR2/YJL034W Literature Guide Help

Other names published for KAR2: GRP78, BIP, Hsp70 family ATPase KAR2, YJL034W

KAR2 - Protein Sequence Features (13)

ReferenceOther Genes Addressed
Hale SJ, et al.  (2010) Interactions between Kar2p and its nucleotide exchange factors Sil1p and Lhs1p are mechanistically distinct. J Biol Chem 285(28):21600-6
Vembar SS, et al.  (2010) J domain co-chaperone specificity defines the role of BiP during protein translocation. J Biol Chem 285(29):22484-94
Merksamer PI, et al.  (2008) Real-time redox measurements during endoplasmic reticulum stress reveal interlinked protein folding functions. Cell 135(5):933-47
Todd-Corlett A, et al.  (2007) Lobe IB of the ATPase domain of Kar2p/BiP interacts with Ire1p to negatively regulate the unfolded protein response in Saccharomyces cerevisiae. J Mol Biol 367(3):770-87
Kabani M, et al.  (2003) Dependence of endoplasmic reticulum-associated degradation on the peptide binding domain and concentration of BiP. Mol Biol Cell 14(8):3437-48
Kimata Y, et al.  (2003) Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins. Mol Biol Cell 14(6):2559-69
Chevalier M, et al.  (2000) Interaction of murine BiP/GRP78 with the DnaJ homologue MTJ1. J Biol Chem 275(26):19620-7
Kabani M, et al.  (2000) Sls1p stimulates Sec63p-mediated activation of Kar2p in a conformation-dependent manner in the yeast endoplasmic reticulum. Mol Cell Biol 20(18):6923-34
Hamilton TG, et al.  (1999) Cer1p functions as a molecular chaperone in the endoplasmic reticulum of Saccharomyces cerevisiae. Mol Cell Biol 19(8):5298-307
Tokunaga M, et al.  (1998) Characterization of deletion mutations in the carboxy-terminal peptide-binding domain of the Kar2 protein in Saccharomyces cerevisiae. Yeast 14(14):1285-95
Kawamura-Watabe A and Tokunaga M  (1997) Isolation and characterization of kar2-404 mutation in Saccharomyces cerevisiae. Biosci Biotechnol Biochem 61(7):1172-8
Boorstein WR, et al.  (1994) Molecular evolution of the HSP70 multigene family. J Mol Evol 38(1):1-17
Latterich M and Schekman R  (1994) The karyogamy gene KAR2 and novel proteins are required for ER-membrane fusion. Cell 78(1):87-98