SIR4/YDR227W Literature Guide Help

Other names published for SIR4: ASD1, STE9, UTH2, YDR227W

SIR4 - Protein Sequence Features (24)

ReferenceOther Genes Addressed
Kueng S, et al.  (2012) Regulating repression: roles for the sir4 N-terminus in linker DNA protection and stabilization of epigenetic States. PLoS Genet 8(5):e1002727
Zill OA, et al.  (2012) Evolutionary analysis of heterochromatin protein compatibility by interspecies complementation in Saccharomyces. Genetics 192(3):1001-14
Fredrickson EK, et al.  (2011) Exposed hydrophobicity is a key determinant of nuclear quality control degradation. Mol Biol Cell 22(13):2384-95
Horigome C, et al.  (2011) Ribosome biogenesis factors bind a nuclear envelope SUN domain protein to cluster yeast telomeres.LID - 10.1038/emboj.2011.267 [doi] EMBO J ()
Zill OA, et al.  (2010) Co-evolution of transcriptional silencing proteins and the DNA elements specifying their assembly. PLoS Biol 8(11):e1000550
Martino F, et al.  (2009) Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro. Mol Cell 33(3):323-34
Brady TL, et al.  (2008) Retrotransposon target site selection by imitation of a cellular protein. Mol Cell Biol 28(4):1230-9
Bupp JM, et al.  (2007) Telomere anchoring at the nuclear periphery requires the budding yeast Sad1-UNC-84 domain protein Mps3. J Cell Biol 179(5):845-54
Chang EJ, et al.  (2007) Prediction of cyclin-dependent kinase phosphorylation substrates. PLoS One 2(7):e656
Clement M, et al.  (2006) The nuclear GTPase Gsp1p can affect proper telomeric function through the Sir4 protein in Saccharomyces cerevisiae. Mol Microbiol 62(2):453-468
King DA, et al.  (2006) Domain structure and protein interactions of the silent information regulator Sir3 revealed by screening a nested deletion library of protein fragments. J Biol Chem 281(29):20107-19
Denison C, et al.  (2005) A proteomic strategy for gaining insights into protein sumoylation in yeast. Mol Cell Proteomics 4(3):246-54
Rudner AD, et al.  (2005) A nonhistone protein-protein interaction required for assembly of the SIR complex and silent chromatin. Mol Cell Biol 25(11):4514-28
Taddei A, et al.  (2005) Multiple pathways tether telomeres and silent chromatin at the nuclear periphery: functional implications for sir-mediated repression. Novartis Found Symp 264:140-56; discussion 156-65, 227-30
Roy R, et al.  (2004) Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing. J Biol Chem 279(1):86-94
Taddei A, et al.  (2004) Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins. EMBO J 23(6):1301-12
Chang JF, et al.  (2003) Structure of the coiled-coil dimerization motif of Sir4 and its interaction with Sir3. Structure 11(6):637-49
Murphy GA, et al.  (2003) The Sir4 C-terminal coiled coil is required for telomeric and mating type silencing in Saccharomyces cerevisiae. J Mol Biol 334(4):769-80
Xu RM  (2003) A pivotal role of the coiled coil of Sir4. Structure 11(6):608-9
Andrulis ED, et al.  (2002) Esc1, a nuclear periphery protein required for Sir4-based plasmid anchoring and partitioning. Mol Cell Biol 22(23):8292-301
Xie W, et al.  (2001) Targeting of the yeast Ty5 retrotransposon to silent chromatin is mediated by interactions between integrase and Sir4p. Mol Cell Biol 21(19):6606-14
Ansari A and Gartenberg MR  (1997) The yeast silent information regulator Sir4p anchors and partitions plasmids. Mol Cell Biol 17(12):7061-8
Moazed D, et al.  (1997) Silent information regulator protein complexes in Saccharomyces cerevisiae: a SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3. Proc Natl Acad Sci U S A 94(6):2186-91
Marshall M, et al.  (1987) Functional domains of SIR4, a gene required for position effect regulation in Saccharomyces cerevisiae. Mol Cell Biol 7(12):4441-52