CDC34/YDR054C Literature Guide Help

Other names published for CDC34: DNA6, UBC3, SCF E2 ubiquitin-protein ligase catalytic subunit CDC34, YDR054C

CDC34 - Protein Sequence Features (20)

ReferenceOther Genes Addressed
Cocklin R, et al.  (2011) New insight into the role of the Cdc34 ubiquitin-conjugating enzyme in cell cycle regulation via Ace2 and Sic1. Genetics 187(3):701-15
Lass A, et al.  (2011) The loop-less tmCdc34 E2 mutant defective in polyubiquitination in vitro and in vivo supports yeast growth in a manner dependent on Ubp14 and Cka2. Cell Div 6(1):7
Papaleo E, et al.  (2011) An acidic loop and cognate phosphorylation sites define a molecular switch that modulates ubiquitin charging activity in cdc34-like enzymes. PLoS Comput Biol 7(5):e1002056
Sadowski M, et al.  (2010) Molecular basis for lysine specificity in the yeast ubiquitin-conjugating enzyme Cdc34. Mol Cell Biol 30(10):2316-29
Kleiger G, et al.  (2009) The Acidic Tail of the Cdc34 Ubiquitin-conjugating Enzyme Functions in Both Binding to and Catalysis with Ubiquitin Ligase SCFCdc4. J Biol Chem 284(52):36012-23
Bazirgan OA and Hampton RY  (2008) Cue1p is an activator of Ubc7p E2 activity in vitro and in vivo. J Biol Chem 283(19):12797-810
Coccetti P, et al.  (2008) The CK2 phosphorylation of catalytic domain of Cdc34 modulates its activity at the G1 to S transition in Saccharomyces cerevisiae. Cell Cycle 7(10):1391-401
Lee I and Schindelin H  (2008) Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes. Cell 134(2):268-78
Li Z, et al.  (2008) Cdc34p Ubiquitin-Conjugating Enzyme Is a Component of the Tombusvirus Replicase Complex and Ubiquitinates p33 Replication Protein. J Virol 82(14):6911-26
Sadowski M, et al.  (2007) Cdc34 C-terminal tail phosphorylation regulates Skp1/cullin/F-box (SCF)-mediated ubiquitination and cell cycle progression. Biochem J 405(3):569-81
Scaglione KM, et al.  (2007) SCF E3-mediated autoubiquitination negatively regulates activity of Cdc34 E2 but plays a nonessential role in the catalytic cycle in vitro and in vivo. Mol Cell Biol 27(16):5860-70
Barz T, et al.  (2006) Control of methionine biosynthesis genes by protein kinase CK2-mediated phosphorylation of Cdc34. Cell Mol Life Sci 63(18):2183-90
Petroski MD and Deshaies RJ  (2005) Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34. Cell 123(6):1107-20
Catic A, et al.  (2004) Preferred in vivo ubiquitination sites. Bioinformatics 20(18):3302-7
Varelas X, et al.  (2003) Cdc34 self-association is facilitated by ubiquitin thiolester formation and is required for its catalytic activity. Mol Cell Biol 23(15):5388-400
Ptak C, et al.  (2001) Creation of a pluripotent ubiquitin-conjugating enzyme. Mol Cell Biol 21(19):6537-48
Reymond F, et al.  (2000) Association of human ubiquitin-conjugating enzyme CDC34 with the mitotic spindle in anaphase. J Cell Sci 113 ( Pt 10):1687-94
Ptak C, et al.  (1994) Functional and physical characterization of the cell cycle ubiquitin-conjugating enzyme CDC34 (UBC3). Identification of a functional determinant within the tail that facilitates CDC34 self-association. J Biol Chem 269(42):26539-45
Banerjee A, et al.  (1993) The bacterially expressed yeast CDC34 gene product can undergo autoubiquitination to form a multiubiquitin chain-linked protein. J Biol Chem 268(8):5668-75
Goebl MG, et al.  (1988) The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzyme. Science 241(4871):1331-5