SIR2/YDL042C Literature Guide Help

Other names published for SIR2: MAR1, YDL042C

SIR2 - Protein Sequence Features (19)

ReferenceOther Genes Addressed
Froyd CA and Rusche LN  (2011) The duplicated deacetylases Sir2 and Hst1 subfunctionalized by acquiring complementary inactivating mutations. Mol Cell Biol 31(16):3351-65
Oppikofer M, et al.  (2011) A dual role of H4K16 acetylation in the establishment of yeast silent chromatin.LID - 10.1038/emboj.2011.170 [doi] EMBO J ()
Wu CS, et al.  (2011) Targeted sister chromatid cohesion by sir2. PLoS Genet 7(2):e1002000
Lynch PJ and Rusche LN  (2010) An auxiliary silencer and a boundary element maintain high levels of silencing proteins at HMR in Saccharomyces cerevisiae. Genetics 185(1):113-27
Zill OA, et al.  (2010) Co-evolution of transcriptional silencing proteins and the DNA elements specifying their assembly. PLoS Biol 8(11):e1000550
Koch MR and Pillus L  (2009) The glucanosyltransferase Gas1 functions in transcriptional silencing. Proc Natl Acad Sci U S A 106(27):11224-9
Chou CC, et al.  (2008) Bypassing Sir2 and O-acetyl-ADP-ribose in transcriptional silencing. Mol Cell 31(5):650-9
Darst RP, et al.  (2008) Slx5 promotes transcriptional silencing and is required for robust growth in the absence of Sir2. Mol Cell Biol 28(4):1361-72
Wang CL, et al.  (2008) A yeast sir2 mutant temperature sensitive for silencing. Genetics 180(4):1955-62
Hickman M, et al.  (2007) Isolation and Characterization of Conditional Alleles of the Yeast SIR2 Gene. J Mol Biol 367(5):1246-57
Hickman MA and Rusche LN  (2007) Substitution as a mechanism for genetic robustness: the duplicated deacetylases Hst1p and Sir2p in Saccharomyces cerevisiae. PLoS Genet 3(8):e126
Mead J, et al.  (2007) Swapping the gene-specific and regional silencing specificities of the Hst1 and Sir2 histone deacetylases. Mol Cell Biol 27(7):2466-75
Cubizolles F, et al.  (2006) A homotrimer-heterotrimer switch in Sir2 structure differentiates rDNA and telomeric silencing. Mol Cell 21(6):825-36
Kirchmaier AL and Rine J  (2006) Cell cycle requirements in assembling silent chromatin in Saccharomyces cerevisiae. Mol Cell Biol 26(3):852-62
Li C, et al.  (2006) Sir2 represses endogenous polymerase II transcription units in the ribosomal DNA nontranscribed spacer. Mol Biol Cell 17(9):3848-59
Pandey R, et al.  (2002) Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes. Nucleic Acids Res 30(23):5036-55
Bedalov A, et al.  (2001) Identification of a small molecule inhibitor of Sir2p. Proc Natl Acad Sci U S A 98(26):15113-8
Perrod S, et al.  (2001) A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast. EMBO J 20(1-2):197-209
Cockell MM, et al.  (2000) Analysis of Sir2p domains required for rDNA and telomeric silencing in Saccharomyces cerevisiae. Genetics 154(3):1069-83