IRE1/YHR079C Literature Guide Help

Other names published for IRE1: ERN1, YHR079C

IRE1 - Protein Sequence Features (20)

ReferenceOther Genes Addressed
Rubio C, et al.  (2011) Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity. J Cell Biol 193(1):171-84
Shechtman CF, et al.  (2011) Loss of Subcellular Lipid Transport Due to ARV1 Deficiency Disrupts Organelle Homeostasis and Activates the Unfolded Protein Response. J Biol Chem 286(14):11951-9
Poothong J, et al.  (2010) Domain compatibility in Ire1 kinase is critical for the unfolded protein response. FEBS Lett 584(14):3203-8
Nguyen Ba AN, et al.  (2009) NLStradamus: a simple Hidden Markov Model for nuclear localization signal prediction. BMC Bioinformatics 10:202
Lee KP, et al.  (2008) Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing. Cell 132(1):89-100
Kimata Y, et al.  (2007) Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins. J Cell Biol 179(1):75-86
Oikawa D, et al.  (2007) Self-association and BiP dissociation are not sufficient for activation of the ER stress sensor Ire1. J Cell Sci 120(Pt 9):1681-8
Goffin L, et al.  (2006) The unfolded protein response transducer Ire1p contains a nuclear localization sequence recognized by multiple beta importins. Mol Biol Cell 17(12):5309-23
Guo J and Polymenis M  (2006) Dcr2 targets Ire1 and downregulates the unfolded protein response in Saccharomyces cerevisiae. EMBO Rep 7(11):1124-7
Credle JJ, et al.  (2005) On the mechanism of sensing unfolded protein in the endoplasmic reticulum. Proc Natl Acad Sci U S A 102(52):18773-84
Oikawa D, et al.  (2005) An essential dimer-forming subregion of the endoplasmic reticulum stress sensor Ire1. Biochem J 391(Pt 1):135-42
Kimata Y, et al.  (2004) A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1. J Cell Biol 167(3):445-56
Papa FR, et al.  (2003) Bypassing a kinase activity with an ATP-competitive drug. Science 302(5650):1533-7
Dong B, et al.  (2001) Basis for regulated RNA cleavage by functional analysis of RNase L and Ire1p. RNA 7(3):361-73
Nock S, et al.  (2001) Purification and activity assays of the catalytic domains of the kinase/endoribonuclease Ire1p from Saccharomyces cerevisiae. Methods Enzymol 342():3-10
Liu CY, et al.  (2000) Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum. J Biol Chem 275(32):24881-5
Ponting CP  (2000) Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function prediction. Biochem J 351 Pt 2():527-35
Shamu CE and Walter P  (1996) Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus. EMBO J 15(12):3028-39
Mori K, et al.  (1993) A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell 74(4):743-56
Nikawa J and Yamashita S  (1992) IRE1 encodes a putative protein kinase containing a membrane-spanning domain and is required for inositol phototrophy in Saccharomyces cerevisiae. Mol Microbiol 6(11):1441-6