ATG8/YBL078C Literature Guide Help

Other names published for ATG8: APG8, CVT5, AUT7, YBL078C

ATG8 - Protein Sequence Features (13)

ReferenceOther Genes Addressed
Alemu EA, et al.  (2012) ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs. J Biol Chem 287(47):39275-90
Nakatogawa H, et al.  (2012) The autophagy-related protein kinase Atg1 interacts with the ubiquitin-like protein Atg8 via the Atg8 family interacting motif to facilitate autophagosome formation. J Biol Chem 287(34):28503-7
Hong SB, et al.  (2011) Insights into noncanonical E1 enzyme activation from the structure of autophagic E1 Atg7 with Atg8. Nat Struct Mol Biol 18(12):1323-30
Noda NN, et al.  (2011) Structural basis of Atg8 activation by a homodimeric E1, Atg7. Mol Cell 44(3):462-75
Schwarten M, et al.  (2010) Solution structure of Atg8 reveals conformational polymorphism of the N-terminal domain. Biochem Biophys Res Commun 395(3):426-31
Yamaguchi M, et al.  (2010) Autophagy-related Protein 8 (Atg8) Family Interacting Motif in Atg3 Mediates the Atg3-Atg8 Interaction and Is Crucial for the Cytoplasm-to-Vacuole Targeting Pathway. J Biol Chem 285(38):29599-607
Noda NN, et al.  (2008) Structural basis of target recognition by Atg8/LC3 during selective autophagy. Genes Cells 13(12):1211-8
Fass E, et al.  (2007) Identification of essential residues for the C-terminal cleavage of the mammalian LC3: a lesson from yeast Atg8. Autophagy 3(1):48-50
Amar N, et al.  (2006) Two newly identified sites in the ubiquitin-like protein Atg8 are essential for autophagy. EMBO Rep 7(6):635-42
Sugawara K, et al.  (2004) The crystal structure of microtubule-associated protein light chain 3, a mammalian homologue of Saccharomyces cerevisiae Atg8. Genes Cells 9(7):611-8
Komatsu M, et al.  (2001) The C-terminal region of an Apg7p/Cvt2p is required for homodimerization and is essential for its E1 activity and E1-E2 complex formation. J Biol Chem 276(13):9846-54
Ichimura Y, et al.  (2000) A ubiquitin-like system mediates protein lipidation. Nature 408(6811):488-92
Lang T, et al.  (1998) Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole. EMBO J 17(13):3597-607