COX2/Q0250 Literature Guide Help

Other names published for COX2: OXI1, OXII, cytochrome c oxidase subunit 2, Q0250

COX2 - Protein Processing/Modification/Regulation (38)

ReferenceOther Genes Addressed
Bulteau AL, et al.  (2012) Changes in mitochondrial glutathione levels and protein thiol oxidation in ?yfh1 yeast cells and the lymphoblasts of patients with Friedreich's ataxia. Biochim Biophys Acta 1822(2):212-25
Cruz-Torres V, et al.  (2012) The cytosol-synthesized subunit II (Cox2) precursor with the point mutation W56R is correctly processed in yeast mitochondria to rescue cytochrome oxidase. Biochim Biophys Acta 1817(12):2128-39
Elliott LE, et al.  (2012) Multiple roles of the Cox20 chaperone in assembly of Saccharomyces cerevisiae cytochrome c oxidase. Genetics 190(2):559-67
Keil M, et al.  (2012) Oxa1-ribosome complexes coordinate the assembly of cytochrome C oxidase in mitochondria. J Biol Chem 287(41):34484-93
Schreiner B, et al.  (2012) Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria. Mol Biol Cell 23(22):4335-46
Hori A, et al.  (2011) Mitochondrial fusion increases the mitochondrial DNA copy number in budding yeast. Genes Cells 16(5):527-44
Reinhold R, et al.  (2011) Mimicking a SURF1 allele reveals uncoupling of cytochrome c oxidase assembly from translational regulation in yeast. Hum Mol Genet 20(12):2379-93
Bestwick M, et al.  (2010) Analysis of Leigh Syndrome Mutations in the Yeast SURF1 Homolog Reveals a New Member of the Cytochrome Oxidase Assembly Factor Family. Mol Cell Biol 30(18):4480-91
Di Bella D, et al.  (2010) Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28. Nat Genet 42(4):313-21
Mathieu L, et al.  (2010) A mutational analysis reveals new functional interactions between domains of the Oxa1 protein in Saccharomyces cerevisiae. Mol Microbiol 75(2):474-88
Mick DU, et al.  (2010) Coa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria. J Cell Biol 191(1):141-54
Fiumera HL, et al.  (2009) Translocation and Assembly of Mitochondrially Coded Saccharomyces cerevisiae Cytochrome c Oxidase Subunit Cox2 by Oxa1 and Yme1 in the Absence of Cox18. Genetics 182(2):519-28
Jia L, et al.  (2009) Mapping of the Saccharomyces cerevisiae Oxa1-mitochondrial ribosome interface and identification of MrpL40, a ribosomal protein in close proximity to Oxa1 and critical for oxidative phosphorylation complex assembly. Eukaryot Cell 8(11):1792-802
Horn D, et al.  (2008) Cmc1p is a conserved mitochondrial twin CX9C protein involved in cytochrome c oxidase biogenesis. Mol Cell Biol 28(13):4354-64
Kutner J, et al.  (2008) Mitochondrial release factor in yeast: interplay of functional domains. Curr Genet 53(3):185-192
Wang X, et al.  (2008) Reduced cytosolic protein synthesis suppresses mitochondrial degeneration. Nat Cell Biol 10(9):1090-7
Graef M, et al.  (2007) Substrate recognition by AAA+ ATPases: distinct substrate binding modes in ATP-dependent protease Yme1 of the mitochondrial intermembrane space. Mol Cell Biol 27(7):2476-85
Kirchman PA and Botta G  (2007) Copper supplementation increases yeast life span under conditions requiring respiratory metabolism. Mech Ageing Dev 128(2):187-95
Graef M and Langer T  (2006) Substrate specific consequences of central pore mutations in the i-AAA protease Yme1 on substrate engagement. J Struct Biol 156(1):101-8
Augustin S, et al.  (2005) Characterization of peptides released from mitochondria: evidence for constant proteolysis and peptide efflux. J Biol Chem 280(4):2691-9
Saracco SA and Fox TD  (2002) Cox18p is required for export of the mitochondrially encoded Saccharomyces cerevisiae Cox2p C-tail and interacts with Pnt1p and Mss2p in the inner membrane. Mol Biol Cell 13(4):1122-31
Broadley SA, et al.  (2001) Peripheral mitochondrial inner membrane protein, Mss2p, required for export of the mitochondrially coded Cox2p C tail in Saccharomyces cerevisiae. Mol Cell Biol 21(22):7663-72
Hell K, et al.  (2001) Oxa1p acts as a general membrane insertion machinery for proteins encoded by mitochondrial DNA. EMBO J 20(6):1281-8
Manon S, et al.  (2001) Mitochondrial AAA-type protease Yme1p is involved in Bax effects on cytochrome c oxidase. Biochem Biophys Res Commun 289(5):1314-9
Nijtmans LG, et al.  (2001) Shy1p occurs in a high molecular weight complex and is required for efficient assembly of cytochrome c oxidase in yeast. FEBS Lett 498(1):46-51
Saint-Georges Y, et al.  (2001) Role of positively charged transmembrane segments in the insertion and assembly of mitochondrial inner-membrane proteins. Proc Natl Acad Sci U S A 98(24):13814-9
Chacinska A, et al.  (2000) Prion-dependent switching between respiratory competence and deficiency in the yeast nam9-1 mutant. Mol Cell Biol 20(19):7220-9
Hell K, et al.  (2000) Identification of Cox20p, a novel protein involved in the maturation and assembly of cytochrome oxidase subunit 2. J Biol Chem 275(7):4571-8
Lemaire C, et al.  (2000) Absence of the mitochondrial AAA protease Yme1p restores F0-ATPase subunit accumulation in an oxa1 deletion mutant of Saccharomyces cerevisiae. J Biol Chem 275(31):23471-5
Beilharz T, et al.  (1998) A toxic fusion protein accumulating between the mitochondrial membranes inhibits protein assembly in vivo. J Biol Chem 273(52):35268-72