CDC6/YJL194W Literature Guide Help

Other names published for CDC6: AAA family ATPase CDC6, YJL194W

CDC6 - Protein Processing/Modification/Regulation (26)

ReferenceOther Genes Addressed
Bremmer SC, et al.  (2012) Cdc14 phosphatases preferentially dephosphorylate a subset of cyclin-dependent kinase (Cdk) sites containing phosphoserine. J Biol Chem 287(3):1662-9
Gidvani RD, et al.  (2012) A quantitative model of the initiation of DNA replication in Saccharomyces cerevisiae predicts the effects of system perturbations. BMC Syst Biol 6(1):78
Kim DH, et al.  (2012) The Hect domain E3 ligase Tom1 and the F-box protein Dia2 control Cdc6 degradation in G1 phase. J Biol Chem 287(53):44212-20
Ofir A and Kornitzer D  (2010) Candida albicans Cyclin Clb4 Carries S-Phase Cyclin Activity. Eukaryot Cell 9(9):1311-9
Zhai Y, et al.  (2010) Cdc14p resets the competency of replication licensing by dephosphorylating multiple initiation proteins during mitotic exit in budding yeast. J Cell Sci 123(Pt 22):3933-43
Drury LS and Diffley JF  (2009) Factors affecting the diversity of DNA replication licensing control in eukaryotes. Curr Biol 19(6):530-5
Remus D, et al.  (2009) Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. Cell 139(4):719-30
Boronat S and Campbell JL  (2007) Mitotic Cdc6 stabilizes anaphase-promoting complex substrates by a partially Cdc28-independent mechanism, and this stabilization is suppressed by deletion of Cdc55. Mol Cell Biol 27(3):1158-71
Hall JR, et al.  (2007) Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damage. Mol Biol Cell 18(9):3340-50
Holt LJ, et al.  (2007) Evolution of Ime2 phosphorylation sites on Cdk1 substrates provides a mechanism to limit the effects of the phosphatase Cdc14 in meiosis. Mol Cell 25(5):689-702
Honey S and Futcher B  (2007) Roles of the CDK phosphorylation sites of yeast Cdc6 in chromatin binding and rereplication. Mol Biol Cell 18(4):1324-36
Moses AM, et al.  (2007) Regulatory evolution in proteins by turnover and lineage-specific changes of cyclin-dependent kinase consensus sites. Proc Natl Acad Sci U S A 104(45):17713-8
Speck C and Stillman B  (2007) Cdc6 ATPase activity regulates ORC x Cdc6 stability and the selection of specific DNA sequences as origins of DNA replication. J Biol Chem 282(16):11705-14
Jensen LJ, et al.  (2006) Co-evolution of transcriptional and post-translational cell-cycle regulation. Nature 443(7111):594-7
Moriya H, et al.  (2006) In vivo robustness analysis of cell division cycle genes in Saccharomyces cerevisiae. PLoS Genet 2(7):e111
Loog M and Morgan DO  (2005) Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates. Nature 434(7029):104-8
Mimura S, et al.  (2004) Phosphorylation-dependent binding of mitotic cyclins to Cdc6 contributes to DNA replication control. Nature 431(7012):1118-23
Burhans WC, et al.  (2003) Apoptosis-like yeast cell death in response to DNA damage and replication defects. Mutat Res 532(1-2):227-43
Luo KQ, et al.  (2003) Regulation of the localization and stability of Cdc6 in living yeast cells. Biochem Biophys Res Commun 306(4):851-9
Blanchard F, et al.  (2002) Targeted destruction of DNA replication protein Cdc6 by cell death pathways in mammals and yeast. Mol Biol Cell 13(5):1536-49
Jang SW, et al.  (2001) Identification of Cdc6 protein domains involved in interaction with Mcm2 protein and Cdc4 protein in budding yeast cells. Biochem J 354(Pt 3):655-61
Weinreich M, et al.  (2001) Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle. Proc Natl Acad Sci U S A 98(20):11211-7
Calzada A, et al.  (2000) The stability of the Cdc6 protein is regulated by cyclin-dependent kinase/cyclin B complexes in Saccharomyces cerevisiae. J Biol Chem 275(13):9734-41
Drury LS, et al.  (2000) The cyclin-dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle. Curr Biol 10(5):231-40
Elsasser S, et al.  (1999) Phosphorylation controls timing of Cdc6p destruction: A biochemical analysis. Mol Biol Cell 10(10):3263-77
Sanchez M, et al.  (1999) The Cdc6 protein is ubiquitinated in vivo for proteolysis in Saccharomyces cerevisiae. J Biol Chem 274(13):9092-7