SIR2/YDL042C Literature Guide Help

Other names published for SIR2: MAR1, YDL042C

SIR2 - Protein Processing/Modification/Regulation (22)

ReferenceOther Genes Addressed
Chang CS, et al.  (2012) Suppression Analysis of esa1 Mutants in Saccharomyces cerevisiae Links NAB3 to Transcriptional Silencing and Nucleolar Functions. G3 (Bethesda) 2(10):1223-32
Laskar S, et al.  (2011) HSP90 Controls SIR2 Mediated Gene Silencing. PLoS One 6(8):e23406
Lindstrom DL, et al.  (2011) Replicative Age Induces Mitotic Recombination in the Ribosomal RNA Gene Cluster of Saccharomyces cerevisiae. PLoS Genet 7(3):e1002015
Wang CY, et al.  (2011) The C-Terminus of Histone H2B Is Involved in Chromatin Compaction Specifically at Telomeres, Independently of Its Monoubiquitylation at Lysine 123. PLoS One 6(7):e22209
Lynch PJ and Rusche LN  (2010) An auxiliary silencer and a boundary element maintain high levels of silencing proteins at HMR in Saccharomyces cerevisiae. Genetics 185(1):113-27
Ozaydin B and Rine J  (2010) Expanded Roles of the Origin Recognition Complex in the Architecture and Function of Silenced Chromatin in Saccharomyces cerevisiae. Mol Cell Biol 30(3):626-39
Dang W, et al.  (2009) Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature 459(7248):802-7
Reverter-Branchat G, et al.  (2007) Chronological and replicative life-span extension in Saccharomyces cerevisiae by increased dosage of alcohol dehydrogenase 1. Microbiology 153(Pt 11):3667-3676
Kaeberlein M, et al.  (2005) Substrate-specific activation of sirtuins by resveratrol. J Biol Chem 280(17):17038-45
Michel AH, et al.  (2005) Spontaneous rDNA copy number variation modulates Sir2 levels and epigenetic gene silencing. Genes Dev 19(10):1199-210
Couzin J  (2004) Scientific community. Aging research's family feud. Science 303(5662):1276-9
Dasgupta A, et al.  (2004) Sir Antagonist 1 (San1) is a ubiquitin ligase. J Biol Chem 279(26):26830-8
Davenport RJ  (2004) UnSIRtainty principle. Conflicting results underscore questions about how calorie restriction activates yeast longevity enzyme. Sci Aging Knowledge Environ 2004(1):nf5
Gallo CM, et al.  (2004) Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity. Mol Cell Biol 24(3):1301-12
Lin SJ, et al.  (2004) Calorie restriction extends yeast life span by lowering the level of NADH. Genes Dev 18(1):12-6
Sauve AA and Schramm VL  (2004) SIR2: the biochemical mechanism of NAD(+)-dependent protein deacetylation and ADP-ribosyl enzyme intermediates. Curr Med Chem 11(7):807-26
Anderson RM, et al.  (2003) Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Nature 423(6936):181-5
Anderson RM, et al.  (2003) Yeast life-span extension by calorie restriction is independent of NAD fluctuation. Science 302(5653):2124-6
Hirao M, et al.  (2003) Identification of selective inhibitors of NAD+-dependent deacetylases using phenotypic screens in yeast. J Biol Chem 278(52):52773-82
Jackson MD, et al.  (2003) Mechanism of nicotinamide inhibition and transglycosidation by Sir2 histone/protein deacetylases. J Biol Chem 278(51):50985-98
San-Segundo PA and Roeder GS  (2000) Role for the silencing protein Dot1 in meiotic checkpoint control. Mol Biol Cell 11(10):3601-15
Tanny JC, et al.  (1999) An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing. Cell 99(7):735-45