IRE1/YHR079C Literature Guide Help

Other names published for IRE1: ERN1, YHR079C

IRE1 - Protein Processing/Modification/Regulation (9)

ReferenceOther Genes Addressed
Gardner BM and Walter P  (2011) Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response. Science 333(6051):1891-4
Rubio C, et al.  (2011) Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity. J Cell Biol 193(1):171-84
Wiseman RL, et al.  (2010) Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1. Mol Cell 38(2):291-304
Guo J and Polymenis M  (2006) Dcr2 targets Ire1 and downregulates the unfolded protein response in Saccharomyces cerevisiae. EMBO Rep 7(11):1124-7
Oikawa D, et al.  (2005) An essential dimer-forming subregion of the endoplasmic reticulum stress sensor Ire1. Biochem J 391(Pt 1):135-42
Okamura K, et al.  (2000) Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast. Biochem Biophys Res Commun 279(2):445-50
Shamu CE and Walter P  (1996) Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus. EMBO J 15(12):3028-39
Welihinda AA and Kaufman RJ  (1996) The unfolded protein response pathway in Saccharomyces cerevisiae. Oligomerization and trans-phosphorylation of Ire1p (Ern1p) are required for kinase activation. J Biol Chem 271(30):18181-7
Mori K, et al.  (1993) A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell 74(4):743-56