TOP2/YNL088W Literature Guide Help

Other names published for TOP2: TOR3, TRF3, DNA topoisomerase 2, YNL088W

TOP2 - Protein Physical Properties (11)

ReferenceOther Genes Addressed
Schmidt BH, et al.  (2012) Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity. Nat Struct Mol Biol 19(11):1147-54
Schmidt BH, et al.  (2010) A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases. Nature 465(7298):641-4
Mueller-Planitz F and Herschlag D  (2008) Coupling between ATP binding and DNA cleavage by DNA topoisomerase II: A unifying kinetic and structural mechanism. J Biol Chem 283(25):17463-76
Moro S, et al.  (2004) Interaction model for anthracycline activity against DNA topoisomerase II. Biochemistry 43(23):7503-13
Trigueros S, et al.  (2004) Asymmetric removal of supercoils suggests how topoisomerase II simplifies DNA topology. J Mol Biol 335(3):723-31
Mondal N, et al.  (2003) Elongation by RNA polymerase II on chromatin templates requires topoisomerase activity. Nucleic Acids Res 31(17):5016-24
Baird CL, et al.  (2001) The ATPase reaction cycle of yeast DNA topoisomerase II. Slow rates of ATP resynthesis and P(i) release. J Biol Chem 276(30):27893-8
Heddle JG, et al.  (2001) The antibiotic microcin B17 is a DNA gyrase poison: characterisation of the mode of inhibition. J Mol Biol 307(5):1223-34
Mizushina Y, et al.  (2000) Structural homology between DNA binding sites of DNA polymerase beta and DNA topoisomerase II. J Mol Biol 304(3):385-95
Bojanowski K, et al.  (1993) DNA topoisomerase II and casein kinase II associate in a molecular complex that is catalytically active. J Biol Chem 268(30):22920-6
Goto T, et al.  (1984) The purification and characterization of DNA topoisomerases I and II of the yeast Saccharomyces cerevisiae. J Biol Chem 259(16):10422-9