Search results for Literature Guide pages at SGD
Your query, YPK1, returned 3 hits to the following gene names:
| Match | Gene Name | Systematic Name | Alias(es) | Position Info | Description |
|---|---|---|---|---|---|
| YPK1 | MCK1 | YNL307C | YPK1, CMS1 | Dual-specificity serine/threonine and tyrosine protein kinase; involved in control of chromosome segregation and in regulating entry into meiosis; interacts with Clb2p and Mih1p; inhibits Clb2p-Cdk1 activity; related to mammalian glycogen synthase kinases of the GSK-3 family; MCK1 has a paralog, YGK3, that arose from the whole genome duplication | |
| YPK1 | TOK1 | YJL093C | DUK1, YKC1, YORK, YPK1 | Outward-rectifier potassium channel of the plasma membrane with two pore domains in tandem, each of which forms a functional channel permeable to potassium; carboxy tail functions to prevent inner gate closures; target of K1 toxin | |
| YPK1 | YPK1 | YKL126W | SLI2 | Serine/threonine protein kinase; phosphorylates and downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p (inhibitors of serine:palmitoyl-coenzyme A transferase) by phosphorylation in response to compromised sphingolipid synthesis; mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; homolog of mammalian kinase SGK; YPK1 has a paralog, YPK2, that arose from the whole genome duplication |
