TIM50/YPL063W Literature Guide Help

Other names published for TIM50: YPL063W

TIM50 - Primary Literature (19)

ReferenceOther Genes Addressed
Reinhold R, et al.  (2012) The channel-forming Sym1 protein is transported by the TIM23 complex in a presequence-independent manner. Mol Cell Biol 32(24):5009-21
Marom M, et al.  (2011) Direct interaction of mitochondrial targeting presequences with purified components of the TIM23 protein complex. J Biol Chem 286(51):43809-15
Qian X, et al.  (2011) Structural basis for the function of Tim50 in the mitochondrial presequence translocase. J Mol Biol 411(3):513-9
Schulz C, et al.  (2011) Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex. J Cell Biol 195(4):643-56
Gevorkyan-Airapetov L, et al.  (2009) Interaction of Tim23 with Tim50 Is Essential for Protein Translocation by the Mitochondrial TIM23 Complex. J Biol Chem 284(8):4865-72
Mokranjac D, et al.  (2009) Role of Tim50 in the transfer of precursor proteins from the outer to the inner membrane of mitochondria. Mol Biol Cell 20(5):1400-7
Tamura Y, et al.  (2009) Tim23-Tim50 pair coordinates functions of translocators and motor proteins in mitochondrial protein import. J Cell Biol 184(1):129-41
Popov-Celeketic D, et al.  (2008) Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria. EMBO J 27(10):1469-80
Meinecke M, et al.  (2006) Tim50 maintains the permeability barrier of the mitochondrial inner membrane. Science 312(5779):1523-6
Vogel F, et al.  (2006) Dynamic subcompartmentalization of the mitochondrial inner membrane. J Cell Biol 175(2):237-47
Wurm CA and Jakobs S  (2006) Differential protein distributions define two sub-compartments of the mitochondrial inner membrane in yeast. FEBS Lett 580(24):5628-34
Chacinska A, et al.  (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29
Meier S, et al.  (2005) Conserved N-terminal negative charges in the Tim17 subunit of the TIM23 translocase play a critical role in the import of preproteins into mitochondria. J Biol Chem 280(9):7777-85
Yamano K, et al.  (2005) The phosphate carrier has an ability to be sorted to either the TIM22 pathway or the TIM23 pathway for its import into yeast mitochondria. J Biol Chem 280(11):10011-7
Chacinska A, et al.  (2003) Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex. EMBO J 22(20):5370-81
Mokranjac D, et al.  (2003) Tim50, a novel component of the TIM23 preprotein translocase of mitochondria. EMBO J 22(4):816-25
Geissler A, et al.  (2002) The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel. Cell 111(4):507-18
Yamamoto H, et al.  (2002) Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes. Cell 111(4):519-28
Stevenson LF, et al.  (2001) A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Proc Natl Acad Sci U S A 98(7):3946-51