MEK1/YOR351C Literature Guide Help

Other names published for MEK1: MRE4, YOR351C

MEK1 - Primary Literature (26)

ReferenceOther Genes Addressed
Chuang CN, et al.  (2012) Mek1 stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during yeast meiosis. Nucleic Acids Res 40(22):11416-27
Callender TL and Hollingsworth NM  (2010) Mek1 suppression of meiotic double-strand break repair is specific to sister chromatids, chromosome autonomous and independent of rec8 cohesin complexes. Genetics 185(3):771-82
Eichinger CS and Jentsch S  (2010) Synaptonemal complex formation and meiotic checkpoint signaling are linked to the lateral element protein Red1. Proc Natl Acad Sci U S A 107(25):11370-5
Govin J, et al.  (2010) Systematic screen reveals new functional dynamics of histones H3 and H4 during gametogenesis. Genes Dev 24(16):1772-86
Kim KP, et al.  (2010) Sister cohesion and structural axis components mediate homolog bias of meiotic recombination. Cell 143(6):924-37
Wu HY, et al.  (2010) Mek1 kinase governs outcomes of meiotic recombination and the checkpoint response. Curr Biol 20(19):1707-16
Niu H, et al.  (2009) Regulation of meiotic recombination via Mek1-mediated Rad54 phosphorylation. Mol Cell 36(3):393-404
Carballo JA, et al.  (2008) Phosphorylation of the axial element protein Hop1 by Mec1/Tel1 ensures meiotic interhomolog recombination. Cell 132(5):758-70
Niu H, et al.  (2007) Mek1 kinase is regulated to suppress double-strand break repair between sister chromatids during budding yeast meiosis. Mol Cell Biol 27(15):5456-67
Niu H, et al.  (2005) Partner choice during meiosis is regulated by Hop1-promoted dimerization of Mek1. Mol Biol Cell 16(12):5804-18
Wan L, et al.  (2004) Mek1 kinase activity functions downstream of RED1 in the regulation of meiotic double strand break repair in budding yeast. Mol Biol Cell 15(1):11-23
Hong EJ and Roeder GS  (2002) A role for Ddc1 in signaling meiotic double-strand breaks at the pachytene checkpoint. Genes Dev 16(3):363-76
de los Santos T, et al.  (2001) A role for MMS4 in the processing of recombination intermediates during meiosis in Saccharomyces cerevisiae. Genetics 159(4):1511-25
Bailis JM and Roeder GS  (2000) Pachytene exit controlled by reversal of Mek1-dependent phosphorylation. Cell 101(2):211-21
Bailis JM, et al.  (2000) Bypass of a meiotic checkpoint by overproduction of meiotic chromosomal proteins. Mol Cell Biol 20(13):4838-48
Zhu H, et al.  (2000) Analysis of yeast protein kinases using protein chips. Nat Genet 26(3):283-9
de los Santos T and Hollingsworth NM  (1999) Red1p, a MEK1-dependent phosphoprotein that physically interacts with Hop1p during meiosis in yeast. J Biol Chem 274(3):1783-90
Bailis JM and Roeder GS  (1998) Synaptonemal complex morphogenesis and sister-chromatid cohesion require Mek1-dependent phosphorylation of a meiotic chromosomal protein. Genes Dev 12(22):3551-63
Hollingsworth NM and Ponte L  (1997) Genetic interactions between HOP1, RED1 and MEK1 suggest that MEK1 regulates assembly of axial element components during meiosis in the yeast Saccharomyces cerevisiae. Genetics 147(1):33-42
Xu L, et al.  (1997) Meiotic cells monitor the status of the interhomolog recombination complex. Genes Dev 11(1):106-18
Purnelle B and Goffeau A  (1996) Nucleotide sequence analysis of a 40 kb segment on the right arm of yeast chromosome XV reveals 18 open reading frames including a new pyruvate kinase and three homologues to chromosome I genes. Yeast 12(14):1475-81
Nag DK, et al.  (1995) Heteroduplex DNA formation and homolog pairing in yeast meiotic mutants. Genetics 141(1):75-86
Burns N, et al.  (1994) Large-scale analysis of gene expression, protein localization, and gene disruption in Saccharomyces cerevisiae. Genes Dev 8(9):1087-105
Ajimura M, et al.  (1993) Identification of new genes required for meiotic recombination in Saccharomyces cerevisiae. Genetics 133(1):51-66
Leem SH and Ogawa H  (1992) The MRE4 gene encodes a novel protein kinase homologue required for meiotic recombination in Saccharomyces cerevisiae. Nucleic Acids Res 20(3):449-57
Rockmill B and Roeder GS  (1991) A meiosis-specific protein kinase homolog required for chromosome synapsis and recombination. Genes Dev 5(12B):2392-404