ISC1/YER019W Literature Guide Help

Other names published for ISC1: inositol phosphosphingolipid phospholipase, YER019W

ISC1 - Primary Literature (23)

ReferenceOther Genes Addressed
Baron JA, et al.  (2013) Superoxide Triggers an Acid Burst in Saccharomyces cerevisiae to Condition the Environment of Glucose-starved Cells. J Biol Chem 288(7):4557-66
Matmati N, et al.  (2013) Identification Of C-18:1 phytoceramide as the candidate lipid mediator for hydroxyurea resistance in yeast. J Biol Chem ()
Barbosa AD, et al.  (2012) Activation of the Hog1p kinase in Isc1p-deficient yeast cells is associated with mitochondrial dysfunction, oxidative stress sensitivity and premature aging. Mech Ageing Dev 133(5):317-30
Rego A, et al.  (2012) Modulation of mitochondrial outer membrane permeabilization and apoptosis by ceramide metabolism. PLoS One 7(11):e48571
Tripathi K, et al.  (2012) Nicotinamide induces Fob1-dependent plasmid integration into chromosome XII in Saccharomyces cerevisiae. FEMS Yeast Res 12(8):949-57
Barbosa AD, et al.  (2011) Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells. Mol Microbiol 81(2):515-27
Lee YJ, et al.  (2011) Defects in very long chain Fatty Acid synthesis enhance alpha-synuclein toxicity in a yeast model of Parkinson's disease. PLoS One 6(1):e15946
Tripathi K, et al.  (2011) Cellular morphogenesis under stress is influenced by the sphingolipid pathway gene ISC1 and DNA integrity checkpoint genes in Saccharomyces cerevisiae. Genetics 189(2):533-47
Usher J, et al.  (2011) Chemical and Synthetic Genetic Array Analysis Identifies Genes that Suppress Xylose Utilization and Fermentation in Saccharomyces cerevisiae. G3 (Bethesda) 1(4):247-58
Wu BX, et al.  (2011) Identification of novel anionic phospholipid binding domains in neutral sphingomyelinase 2 with selective binding preference. J Biol Chem 286(25):22362-71
Guan XL, et al.  (2009) Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology. Mol Biol Cell 20(7):2083-95
Kitagaki H, et al.  (2009) ISC1-dependent Metabolic Adaptation Reveals an Indispensable Role for Mitochondria in Induction of Nuclear Genes during the Diauxic Shift in Saccharomyces cerevisiae. J Biol Chem 284(16):10818-30
Matmati N, et al.  (2009) Hydroxyurea Sensitivity Reveals a Role for ISC1 in the Regulation of G2/M. J Biol Chem 284(13):8241-6
Almeida T, et al.  (2008) Isc1p Plays a Key Role in Hydrogen Peroxide Resistance and Chronological Lifespan through Modulation of Iron Levels and Apoptosis. Mol Biol Cell 19(3):865-876
Kitagaki H, et al.  (2007) Isc1 regulates sphingolipid metabolism in yeast mitochondria. Biochim Biophys Acta 1768(11):2849-61
Cowart LA, et al.  (2006) Distinct roles for de novo versus hydrolytic pathways of sphingolipid biosynthesis in Saccharomyces cerevisiae. Biochem J 393(Pt 3):733-40
Tabuchi M, et al.  (2006) The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation. Mol Cell Biol 26(15):5861-75
Vaena de Avalos S, et al.  (2005) The phosphatidylglycerol/cardiolipin biosynthetic pathway is required for the activation of inositol phosphosphingolipid phospholipase C, Isc1p, during growth of Saccharomyces cerevisiae. J Biol Chem 280(8):7170-7
Vaena de Avalos S, et al.  (2004) Activation and localization of inositol phosphosphingolipid phospholipase C, Isc1p, to the mitochondria during growth of Saccharomyces cerevisiae. J Biol Chem 279(12):11537-45
Okamoto Y, et al.  (2003) Functional analysis of ISC1 by site-directed mutagenesis. Biochemistry 42(25):7855-62
Betz C, et al.  (2002) ISC1-encoded inositol phosphosphingolipid phospholipase C is involved in Na+/Li+ halotolerance of Saccharomyces cerevisiae. Eur J Biochem 269(16):4033-9
Okamoto Y, et al.  (2002) Structural requirements for selective binding of ISC1 to anionic phospholipids. J Biol Chem 277(48):46470-7
Sawai H, et al.  (2000) Identification of ISC1 (YER019w) as inositol phosphosphingolipid phospholipase C in Saccharomyces cerevisiae. J Biol Chem 275(50):39793-8