HMG2/YLR450W Literature Guide Help

Other names published for HMG2: hydroxymethylglutaryl-CoA reductase (NADPH) HMG2, YLR450W

HMG2 - Primary Literature (36)

Results: 1 - 30 of 36 records
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ReferenceOther Genes Addressed
Samanfar B, et al.  (2013) Large-scale investigation of oxygen response mutants in Saccharomyces cerevisiae. Mol Biosyst 9(6):1351-9
Theesfeld CL and Hampton RY  (2013) Insulin-induced gene protein (INSIG)-dependent sterol regulation of Hmg2 endoplasmic reticulum-associated degradation (ERAD) in yeast. J Biol Chem 288(12):8519-30
Brodersen P, et al.  (2012) Isoprenoid biosynthesis is required for miRNA function and affects membrane association of ARGONAUTE 1 in Arabidopsis. Proc Natl Acad Sci U S A 109(5):1778-83
Ignea C, et al.  (2012) Positive genetic interactors of HMG2 identify a new set of genetic perturbations for improving sesquiterpene production in Saccharomyces cerevisiae. Microb Cell Fact 11():162
Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
Dai Z, et al.  (2011) Cloning and characterization of a novel 3-hydroxy-3-methylglutaryl coenzyme A reductase gene from Salvia miltiorrhiza involved in diterpenoid tanshinone accumulation. J Plant Physiol 168(2):148-57
Ignea C, et al.  (2011) Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids. Microb Cell Fact 10():4
Theesfeld CL, et al.  (2011) The sterol-sensing domain (SSD) directly mediates signal-regulated endoplasmic reticulum-associated degradation (ERAD) of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase isozyme Hmg2. J Biol Chem 286(30):26298-307
Bosis E, et al.  (2010) Ssz1 restores endoplasmic reticulum-associated protein degradation in cells expressing defective cdc48-ufd1-npl4 complex by upregulating cdc48. Genetics 184(3):695-706
Mantzouridou F and Tsimidou MZ  (2010) Observations on squalene accumulation in Saccharomyces cerevisiae due to the manipulation of HMG2 and ERG6. FEMS Yeast Res 10(6):699-707
Garza RM, et al.  (2009) Geranylgeranyl Pyrophosphate Is a Potent Regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA Reductase Degradation in Yeast. J Biol Chem 284(51):35368-80
Garza RM, et al.  (2009) In vitro analysis of Hrd1p-mediated retrotranslocation of its multispanning membrane substrate 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase. J Biol Chem 284(22):14710-22
Leszczynska A, et al.  (2009) Investigating the effects of statins on cellular lipid metabolism using a yeast expression system. PLoS One 4(12):e8499
Sato BK, et al.  (2009) Misfolded membrane proteins are specifically recognized by the transmembrane domain of the Hrd1p ubiquitin ligase. Mol Cell 34(2):212-22
Wysocka-Kapcinska M, et al.  (2009) Functional expression of human HMG-CoA reductase in Saccharomyces cerevisiae: a system to analyse normal and mutated versions of the enzyme in the context of statin treatment. J Appl Microbiol 106(3):895-902
Federovitch CM, et al.  (2008) Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiae. Mol Biol Cell 19(10):4506-20
Loertscher J, et al.  (2006) Endoplasmic reticulum-associated degradation is required for cold adaptation and regulation of sterol biosynthesis in the yeast Saccharomyces cerevisiae. Eukaryot Cell 5(4):712-22
Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
Shearer AG and Hampton RY  (2005) Lipid-mediated, reversible misfolding of a sterol-sensing domain protein. EMBO J 24(1):149-59
Giaever G, et al.  (2004) Chemogenomic profiling: identifying the functional interactions of small molecules in yeast. Proc Natl Acad Sci U S A 101(3):793-8
Shearer AG and Hampton RY  (2004) Structural control of endoplasmic reticulum-associated degradation: effect of chemical chaperones on 3-hydroxy-3-methylglutaryl-CoA reductase. J Biol Chem 279(1):188-96
Gardner RG, et al.  (2001) In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation. Mol Cell Biol 21(13):4276-91
Murray BP and Correia MA  (2001) Ubiquitin-dependent 26S proteasomal pathway: a role in the degradation of native human liver CYP3A4 expressed in Saccharomyces cerevisiae? Arch Biochem Biophys 393(1):106-16
Profant DA, et al.  (2000) Mutational analysis of the karmellae-inducing signal in Hmg1p, a yeast HMG-CoA reductase isozyme. Yeast 16(9):811-27
Gardner RG and Hampton RY  (1999) A 'distributed degron' allows regulated entry into the ER degradation pathway. EMBO J 18(21):5994-6004
Kennedy MA, et al.  (1999) Transcriptional regulation of the squalene synthase gene (ERG9) in the yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1445(1):110-22
Gardner R, et al.  (1998) Sequence determinants for regulated degradation of yeast 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein. Mol Biol Cell 9(9):2611-26
Koning AJ, et al.  (1996) Different subcellular localization of Saccharomyces cerevisiae HMG-CoA reductase isozymes at elevated levels corresponds to distinct endoplasmic reticulum membrane proliferations. Mol Biol Cell 7(5):769-89
Parrish ML, et al.  (1995) Identification of the sequences in HMG-CoA reductase required for karmellae assembly. Mol Biol Cell 6(11):1535-47
Sengstag C, et al.  (1990) Genetic and biochemical evaluation of eucaryotic membrane protein topology: multiple transmembrane domains of Saccharomyces cerevisiae 3-hydroxy-3-methylglutaryl coenzyme A reductase. Mol Cell Biol 10(2):672-80
Results: 1 - 30 of 36 records
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