GEF1/YJR040W Literature Guide Help

Other names published for GEF1: CLC, YJR040W

GEF1 - Primary Literature (22)

ReferenceOther Genes Addressed
Sasvari Z, et al.  (2013) The GEF1 proton-chloride exchanger affects tombusvirus replication via regulation of copper metabolism in yeast. J Virol 87(3):1800-10
Sukhai MA, et al.  (2013) Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors. J Clin Invest 123(1):315-28
Minear S, et al.  (2011) Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation. Eukaryot Cell 10(11):1574-81
Braun NA, et al.  (2010) The yeast CLC protein counteracts vesicular acidification during iron starvation. J Cell Sci 123(Pt 13):2342-50
Wege S, et al.  (2010) The proline 160 in the selectivity filter of the Arabidopsis NO(3) (-) /H(+) exchanger AtCLCa is essential for nitrate accumulation in planta. Plant J 63(5):861-9
Jennings ML and Cui J  (2008) Chloride homeostasis in Saccharomyces cerevisiae: high affinity influx, V-ATPase-dependent sequestration, and identification of a candidate Cl- sensor. J Gen Physiol 131(4):379-91
Lopez-Rodriguez A, et al.  (2007) The product of the gene GEF1 of Saccharomyces cerevisiae transports Cl across the plasma membrane. FEMS Yeast Res 7(8):1218-29
Marmagne A, et al.  (2007) Two members of the Arabidopsis CLC (chloride channel) family, AtCLCe and AtCLCf, are associated with thylakoid and Golgi membranes, respectively. J Exp Bot 58(12):3385-93
Oddon DM, et al.  (2007) A CLC chloride channel plays an essential role in copper homeostasis in Aspergillus nidulans at increased extracellular copper concentrations. Biochim Biophys Acta 1768(10):2466-77
Metz J, et al.  (2006) The yeast Arr4p ATPase binds the chloride transporter Gef1p when copper is available in the cytosol. J Biol Chem 281(1):410-7
Wachter A and Schwappach B  (2005) The yeast CLC chloride channel is proteolytically processed by the furin-like protease Kex2p in the first extracellular loop. FEBS Lett 579(5):1149-53
Flis K, et al.  (2002) The Gef1 protein of Saccharomyces cerevisiae is associated with chloride channel activity. Biochem Biophys Res Commun 294(5):1144-50
Bowers K, et al.  (2000) The sodium/proton exchanger Nhx1p is required for endosomal protein trafficking in the yeast Saccharomyces cerevisiae. Mol Biol Cell 11(12):4277-94
Miyazaki H, et al.  (1999) Molecular cloning of CLC chloride channels in Oreochromis mossambicus and their functional complementation of yeast CLC gene mutant. Biochem Biophys Res Commun 255(1):175-81
Davis-Kaplan SR, et al.  (1998) Chloride is an allosteric effector of copper assembly for the yeast multicopper oxidase Fet3p: an unexpected role for intracellular chloride channels. Proc Natl Acad Sci U S A 95(23):13641-5
Gaxiola RA, et al.  (1998) The yeast CLC chloride channel functions in cation homeostasis. Proc Natl Acad Sci U S A 95(7):4046-50
Li L and Kaplan J  (1998) Defects in the yeast high affinity iron transport system result in increased metal sensitivity because of the increased expression of transporters with a broad transition metal specificity. J Biol Chem 273(35):22181-7
Schwappach B, et al.  (1998) Golgi localization and functionally important domains in the NH2 and COOH terminus of the yeast CLC putative chloride channel Gef1p. J Biol Chem 273(24):15110-8
Schmidt-Rose T and Jentsch TJ  (1997) Transmembrane topology of a CLC chloride channel. Proc Natl Acad Sci U S A 94(14):7633-8
Hechenberger M, et al.  (1996) A family of putative chloride channels from Arabidopsis and functional complementation of a yeast strain with a CLC gene disruption. J Biol Chem 271(52):33632-8
Huang ME, et al.  (1994) A voltage-gated chloride channel in the yeast Saccharomyces cerevisiae. J Mol Biol 242(4):595-8
Greene JR, et al.  (1993) The GEF1 gene of Saccharomyces cerevisiae encodes an integral membrane protein; mutations in which have effects on respiration and iron-limited growth. Mol Gen Genet 241(5-6):542-53