ERG11/YHR007C Literature Guide Help

Other names published for ERG11: CYP51, sterol 14-demethylase, YHR007C

ERG11 - Primary Literature (53)

Results: 1 - 30 of 53 records
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ReferenceOther Genes Addressed
Huang Z, et al.  (2013) A functional variomics tool for discovering drug-resistance genes and drug targets. Cell Rep 3(2):577-85
Fiori A and Van Dijck P  (2012) Potent synergistic effect of doxycycline with fluconazole against Candida albicans is mediated by interference with iron homeostasis. Antimicrob Agents Chemother 56(7):3785-96
Hoepfner D, et al.  (2012) An integrated approach for identification and target validation of antifungal compounds active against Erg11p. Antimicrob Agents Chemother 56(8):4233-40
Hull CM, et al.  (2012) Facultative sterol uptake in an ergosterol-deficient clinical isolate of Candida glabrata harboring a missense mutation in ERG11 and exhibiting cross-resistance to azoles and amphotericin B. Antimicrob Agents Chemother 56(8):4223-32
Alcazar-Fuoli L, et al.  (2011) Three-dimensional models of 14a-sterol demethylase (Cyp51A) from Aspergillus lentulus and Aspergillus fumigatus: an insight into differences in voriconazole interaction. Int J Antimicrob Agents 38(5):426-34
Montanes FM, et al.  (2011) Repression of ergosterol biosynthesis is essential for stress resistance and is mediated by the Hog1 MAP kinase and the Mot3 and Rox1 transcription factors. Mol Microbiol 79(4):1008-23
Nkinin SW, et al.  (2011) Pneumocystis carinii sterol 14a-demethylase activity in Saccharomyces cerevisiae erg11 knockout mutant: sterol biochemistry. J Eukaryot Microbiol 58(4):383-92
Spitzer M, et al.  (2011) Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole. Mol Syst Biol 7():499
Kuo D, et al.  (2010) Evolutionary divergence in the fungal response to fluconazole revealed by soft clustering. Genome Biol 11(7):R77
Martel CM, et al.  (2010) Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (Sterol 14{alpha}-Demethylase) Doxycycline-Regulated Mutant and Screening of the Azole Sensitivity of Aspergillus fumigatus Isoenzymes CYP51A and CYP51B. Antimicrob Agents Chemother 54(11):4920-3
Shakoury-Elizeh M, et al.  (2010) Metabolic response to iron deficiency in Saccharomyces cerevisiae. J Biol Chem 285(19):14823-33
Kitahama Y, et al.  (2009) The Construction and Characterization of Self-Sufficient Lanosterol 14-Demethylase Fusion Proteins Consisting of Yeast CYP51 and Its Reductase. Biol Pharm Bull 32(4):558-63
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Warrilow A, et al.  (2008) Expression and Characterization of CYP51, the Ancient Sterol 14-demethylase Activity for Cytochromes P450 (CYP), in the White-Rot Fungus Phanerochaete chrysosporium. Lipids 43(12):1143-53
Chen SH, et al.  (2007) Identification of Y118 Amino Acid Residue in Candida albicans Sterol 14alpha-Demethylase Associated with the Enzyme Activity and Selective Antifungal Activity of Azole Analogues. Biol Pharm Bull 30(7):1246-53
Thompson AM, et al.  (2007) Measurement of the heme affinity for yeast dap1p, and its importance in cellular function. Biochemistry 46(50):14629-37
Chau AS, et al.  (2006) Molecular Basis for Enhanced Activity of Posaconazole against Absidia corymbifera and Rhizopus oryzae. Antimicrob Agents Chemother 50(11):3917-9
Buurman ET, et al.  (2005) Utilization of target-specific, hypersensitive strains of Saccharomyces cerevisiae to determine the mode of action of antifungal compounds. Antimicrob Agents Chemother 49(6):2558-60
Ott RG, et al.  (2005) Flux of sterol intermediates in a yeast strain deleted of the lanosterol C-14 demethylase Erg11p. Biochim Biophys Acta 1735(2):111-8
Lum PY, et al.  (2004) Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell 116(1):121-37
Buckner FS, et al.  (2003) Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase. Mol Biochem Parasitol 132(2):75-81
Morales IJ, et al.  (2003) Characterization of a lanosterol 14 alpha-demethylase from Pneumocystis carinii. Am J Respir Cell Mol Biol 29(2):232-8
Homma K, et al.  (2000) Evidence for recycling of cytochrome P450 sterol 14-demethylase from the cis-Golgi compartment to the endoplasmic reticulum (ER) upon saturation of the ER-retention mechanism. J Biochem 127(5):747-54
Launhardt H and Munder T  (2000) Post-translational regulation of Saccharomyces cerevisiae proteins tagged with the hormone-binding domains of mammalian nuclear receptors. Mol Gen Genet 264(3):317-24
Kontoyiannis DP, et al.  (1999) Overexpression of Erg11p by the regulatable GAL1 promoter confers fluconazole resistance in Saccharomyces cerevisiae. Antimicrob Agents Chemother 43(11):2798-800
Lamb DC, et al.  (1999) Characteristics of the heterologously expressed human lanosterol 14alpha-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human and Candida albicans CYP51 with azole antifungal agents. Yeast 15(9):755-63
Lewis DF, et al.  (1999) Molecular modelling of lanosterol 14 alpha-demethylase (CYP51) from Saccharomyces cerevisiae via homology with CYP102, a unique bacterial cytochrome P450 isoform: quantitative structure-activity relationships (QSARs) within two related series of antifungal azole derivatives. J Enzyme Inhib 14(3):175-92
Launhardt H, et al.  (1998) Drug-induced phenotypes provide a tool for the functional analysis of yeast genes. Yeast 14(10):935-42
Venkateswarlu K, et al.  (1998) NADPH cytochrome P-450 oxidoreductase and susceptibility to ketoconazole. Antimicrob Agents Chemother 42(7):1756-61
Venkateswarlu K, et al.  (1998) The N-terminal membrane domain of yeast NADPH-cytochrome P450 (CYP) oxidoreductase is not required for catalytic activity in sterol biosynthesis or in reconstitution of CYP activity. J Biol Chem 273(8):4492-6
Results: 1 - 30 of 53 records
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