CCC2/YDR270W Literature Guide Help

Other names published for CCC2: Cu(2+)-transporting P-type ATPase CCC2, YDR270W

CCC2 - Primary Literature (43)

ReferenceOther Genes Addressed
Sasvari Z, et al.  (2013) The GEF1 proton-chloride exchanger affects tombusvirus replication via regulation of copper metabolism in yeast. J Virol 87(3):1800-10
Sukhai MA, et al.  (2013) Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors. J Clin Invest 123(1):315-28
Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
Minear S, et al.  (2011) Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation. Eukaryot Cell 10(11):1574-81
Valverde RH, et al.  (2011) Two Serine Residues Control Sequential Steps during Catalysis of the Yeast Copper ATPase through Different Mechanisms That Involve Kinase-mediated Phosphorylations. J Biol Chem 286(9):6879-89
Kennerson ML, et al.  (2010) Missense Mutations in the Copper Transporter Gene ATP7A Cause X-Linked Distal Hereditary Motor Neuropathy. Am J Hum Genet 86(3):343-352
Ruotolo R, et al.  (2008) Membrane transporters and protein traffic networks differentially affecting metal tolerance: a genomic phenotyping study in yeast. Genome Biol 9(4):R67
Tang J, et al.  (2008) Clinical outcomes in Menkes disease patients with a copper-responsive ATP7A mutation, G727R. Mol Genet Metab 95(3):174-81
Valverde RH, et al.  (2008) Cyclic AMP-dependent protein kinase controls energy interconversion during the catalytic cycle of the yeast copper-ATPase. FEBS Lett 582(6):891-5
Banci L, et al.  (2007) Interaction of the two soluble metal-binding domains of yeast Ccc2 with copper(I)-Atx1. Biochem Biophys Res Commun 364(3):645-9
Donsante A, et al.  (2007) Differences in ATP7A gene expression underlie intrafamilial variability in Menkes disease/occipital horn syndrome. J Med Genet 44(8):492-7
Doostzadeh J, et al.  (2007) Chemical genomic profiling for identifying intracellular targets of toxicants producing Parkinson's disease. Toxicol Sci 95(1):182-7
Bertini I, et al.  (2006) Mapping protein-protein interaction by (13)C'-detected heteronuclear NMR spectroscopy. J Biomol NMR 36(2):111-22
Paulsen M, et al.  (2006) Evidence that translation reinitiation leads to a partially functional Menkes protein containing two copper-binding sites. Am J Hum Genet 79(2):214-29
Portmann R and Solioz M  (2005) Purification and functional reconstitution of the human Wilson copper ATPase, ATP7B. FEBS Lett 579(17):3589-95
De Freitas JM, et al.  (2004) Exploratory and confirmatory gene expression profiling of mac1Delta. J Biol Chem 279(6):4450-8
Hsi G, et al.  (2004) Functional assessment of the carboxy-terminus of the Wilson disease copper-transporting ATPase, ATP7B. Genomics 83(3):473-81
Lowe J, et al.  (2004) A mutational study in the transmembrane domain of Ccc2p, the yeast Cu(I)-ATPase, shows different roles for each Cys-Pro-Cys cysteine. J Biol Chem 279(25):25986-94
Serrano R, et al.  (2004) Copper and iron are the limiting factors for growth of the yeast Saccharomyces cerevisiae in an alkaline environment. J Biol Chem 279(19):19698-704
Southron JL, et al.  (2004) Complementation of Saccharomyces cerevisiae ccc2 mutant by a putative P1B-ATPase from Brassica napus supports a copper-transporting function. FEBS Lett 566(1-3):218-22
Xiao Z, et al.  (2004) C-terminal domain of the membrane copper transporter Ctr1 from Saccharomyces cerevisiae binds four Cu(I) ions as a cuprous-thiolate polynuclear cluster: sub-femtomolar Cu(I) affinity of three proteins involved in copper trafficking. J Am Chem Soc 126(10):3081-90
van Dongen EM, et al.  (2004) Copper-dependent protein-protein interactions studied by yeast two-hybrid analysis. Biochem Biophys Res Commun 323(3):789-95
Mercer JF, et al.  (2003) Copper-induced trafficking of the cU-ATPases: a key mechanism for copper homeostasis. Biometals 16(1):175-84
Arnesano F, et al.  (2002) Metallochaperones and metal-transporting ATPases: a comparative analysis of sequences and structures. Genome Res 12(2):255-71
Banci L, et al.  (2002) A new zinc-protein coordination site in intracellular metal trafficking: solution structure of the Apo and Zn(II) forms of ZntA(46-118). J Mol Biol 323(5):883-97
Parisot D, et al.  (2002) clap1, a gene encoding a copper-transporting ATPase involved in the process of infection by the phytopathogenic fungus Colletotrichum lindemuthianum. Mol Genet Genomics 268(2):139-51
Weissman Z, et al.  (2002) Deletion of the copper transporter CaCCC2 reveals two distinct pathways for iron acquisition in Candida albicans. Mol Microbiol 44(6):1551-60
Banci L, et al.  (2001) Solution structure of the yeast copper transporter domain Ccc2a in the apo and Cu(I)-loaded states. J Biol Chem 276(11):8415-26
Voskoboinik I, et al.  (2001) The regulation of catalytic activity of the menkes copper-translocating P-type ATPase. Role of high affinity copper-binding sites. J Biol Chem 276(30):28620-7
Forbes JR and Cox DW  (2000) Copper-dependent trafficking of Wilson disease mutant ATP7B proteins. Hum Mol Genet 9(13):1927-35