MCM4/YPR019W Literature Guide Help

Other names published for MCM4: HCD21, CDC54, YPR019W

MCM4 - Primary Literature (67)

ReferenceOther Genes Addressed
Fernandez-Cid A, et al.  (2013) An ORC/Cdc6/MCM2-7 Complex Is Formed in a Multistep Reaction to Serve as a Platform for MCM Double-Hexamer Assembly. Mol Cell 50(4):577-88
Foltman M, et al.  (2013) Eukaryotic replisome components cooperate to process histones during chromosome replication. Cell Rep 3(3):892-904
Frigola J, et al.  (2013) ATPase-dependent quality control of DNA replication origin licensing. Nature 495(7441):339-43
Ramer MD, et al.  (2013) Dbf4 and Cdc7 Proteins Promote DNA Replication through Interactions with Distinct Mcm2-7 Protein Subunits. J Biol Chem 288(21):14926-35
Sengupta S, et al.  (2013) Dpb2 integrates the leading-strand DNA polymerase into the eukaryotic replisome. Curr Biol 23(7):543-52
Blitzblau HG, et al.  (2012) Separation of DNA replication from the assembly of break-competent meiotic chromosomes. PLoS Genet 8(5):e1002643
Cheng E, et al.  (2012) Genome rearrangements caused by depletion of essential DNA replication proteins in Saccharomyces cerevisiae. Genetics 192(1):147-60
Bruck I and Kaplan DL  (2011) GINS and Sld3 compete with one another for Mcm2-7 and Cdc45 binding. J Biol Chem 286(16):14157-67
Hombauer H, et al.  (2011) Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates. Cell 147(5):1040-53
Li XC and Tye BK  (2011) Ploidy Dictates Repair Pathway Choice under DNA Replication Stress. Genetics 187(4):1031-40
Takara TJ and Bell SP  (2011) Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases. EMBO J 30(24):4885-96
Bochman ML and Schwacha A  (2010) The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'. Nucleic Acids Res 38(18):6078-88
Looke M, et al.  (2010) Relicensing of transcriptionally inactivated replication origins in budding yeast. J Biol Chem 285(51):40004-11
Lydeard JR, et al.  (2010) Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly. Genes Dev 24(11):1133-44
Ma X, et al.  (2010) The effects of oligomerization on Saccharomyces cerevisiae Mcm4/6/7 function. BMC Biochem 11():37
Randell JC, et al.  (2010) Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7. Mol Cell 40(3):353-63
Sheu YJ and Stillman B  (2010) The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4. Nature 463(7277):113-7
Tsakraklides V and Bell SP  (2010) Dynamics of pre-replicative complex assembly. J Biol Chem 285(13):9437-43
Evrin C, et al.  (2009) A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication. Proc Natl Acad Sci U S A 106(48):20240-5
Francis LI, et al.  (2009) Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation. Genes Dev 23(5):643-54
Gambus A, et al.  (2009) A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome. EMBO J 28(19):2992-3004
Li XC, et al.  (2009) Aneuploidy and improved growth are coincident but not causal in a yeast cancer model. PLoS Biol 7(7):e1000161
Remus D, et al.  (2009) Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. Cell 139(4):719-30
Snyder M, et al.  (2009) The Minichromosome Maintenance Proteins 2-7 (MCM2-7) Are Necessary for RNA Polymerase II (Pol II)-mediated Transcription. J Biol Chem 284(20):13466-72
Stead BE, et al.  (2009) ATP binding and hydrolysis by Mcm2 regulate DNA binding by Mcm complexes. J Mol Biol 391(2):301-13
Bochman ML and Schwacha A  (2008) The Mcm2-7 complex has in vitro helicase activity. Mol Cell 31(2):287-93
Bochman ML, et al.  (2008) Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability. Mol Cell Biol 28(19):5865-73
Devault A, et al.  (2008) Interplay between S-Cyclin-dependent Kinase and Dbf4-dependent Kinase in Controlling DNA Replication through Phosphorylation of Yeast Mcm4 N-Terminal Domain. Mol Biol Cell 19(5):2267-77
Kanter DM, et al.  (2008) Mcm subunits can assemble into two different active unwinding complexes. J Biol Chem 283(45):31172-82
Sullivan M, et al.  (2008) Cyclin-specific control of ribosomal DNA segregation. Mol Cell Biol 28(17):5328-36