TOP2/YNL088W Literature Guide Help

Other names published for TOP2: TOR3, TRF3, DNA topoisomerase 2, YNL088W

TOP2 - Primary Literature (111)

ReferenceOther Genes Addressed
Garcia-Rubio ML and Aguilera A  (2012) Topological constraints impair RNA polymerase II transcription and causes instability of plasmid-borne convergent genes. Nucleic Acids Res 40(3):1050-64
Hashash N, et al.  (2012) Topoisomerase II- and Condensin-Dependent Breakage of MEC1(ATR)-Sensitive Fragile Sites Occurs Independently of Spindle Tension, Anaphase, or Cytokinesis. PLoS Genet 8(10):e1002978
Hasinoff BB, et al.  (2012) The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II. Biochem Pharmacol 84(12):1617-26
Joshi RS, et al.  (2012) Topoisomerase II is required for the production of long Pol II gene transcripts in yeast. Nucleic Acids Res 40(16):7907-15
Pedersen JM, et al.  (2012) DNA Topoisomerases Maintain Promoters in a State Competent for Transcriptional Activation in Saccharomyces cerevisiae. PLoS Genet 8(12):e1003128
Schmidt BH, et al.  (2012) Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity. Nat Struct Mol Biol 19(11):1147-54
Baxter J, et al.  (2011) Positive supercoiling of mitotic DNA drives decatenation by topoisomerase II in eukaryotes. Science 331(6022):1328-32
French SL, et al.  (2011) Distinguishing the Roles of Topoisomerases I and II in Relief of Transcription-Induced Torsional Stress in Yeast rRNA Genes. Mol Cell Biol 31(3):482-94
Sperling AS, et al.  (2011) Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase I to enhance recruitment of RNA Pol II in budding yeast. Proc Natl Acad Sci U S A 108(31):12693-8
El Hage A, et al.  (2010) Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis. Genes Dev 24(14):1546-58
Fachinetti D, et al.  (2010) Replication Termination at Eukaryotic Chromosomes Is Mediated by Top2 and Occurs at Genomic Loci Containing Pausing Elements. Mol Cell 39(4):595-605
Renshaw MJ, et al.  (2010) Condensins Promote Chromosome Recoiling during Early Anaphase to Complete Sister Chromatid Separation. Dev Cell 19(2):232-244
Schmidt BH, et al.  (2010) A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases. Nature 465(7298):641-4
Bermejo R, et al.  (2009) Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription. Cell 138(5):870-84
Mendoza M, et al.  (2009) A mechanism for chromosome segregation sensing by the NoCut checkpoint. Nat Cell Biol 11(4):477-83
Baxter J and Diffley JF  (2008) Topoisomerase II inactivation prevents the completion of DNA replication in budding yeast. Mol Cell 30(6):790-802
D'Ambrosio C, et al.  (2008) Condensin-Dependent rDNA Decatenation Introduces a Temporal Pattern to Chromosome Segregation. Curr Biol 18(14):1084-9
Meczes EL, et al.  (2008) The impact of the human DNA topoisomerase II C-terminal domain on activity. PLoS ONE 3(3):e1754
Mueller-Planitz F and Herschlag D  (2008) Coupling between ATP binding and DNA cleavage by DNA topoisomerase II: A unifying kinetic and structural mechanism. J Biol Chem 283(25):17463-76
Rogojina AT and Nitiss JL  (2008) Isolation and Characterization of mAMSA-hypersensitive Mutants: CYTOTOXICITY OF Top2 COVALENT COMPLEXES CONTAINING DNA SINGLE STRAND BREAKS. J Biol Chem 283(43):29239-50
Takahashi Y and Strunnikov A  (2008) In vivo modeling of polysumoylation uncovers targeting of Topoisomerase II to the nucleolus via optimal level of SUMO modification. Chromosoma 117(2):189-98
Takahashi Y, et al.  (2008) Cooperation of sumoylated chromosomal proteins in rDNA maintenance. PLoS Genet 4(10):e1000215
Warsi TH, et al.  (2008) DNA topoisomerase II is a determinant of the tensile properties of yeast centromeric chromatin and the tension checkpoint. Mol Biol Cell 19(10):4421-33
Dong KC and Berger JM  (2007) Structural basis for gate-DNA recognition and bending by type IIA topoisomerases. Nature 450(7173):1201-5
Wilstermann AM, et al.  (2007) Topoisomerase II - drug interaction domains: identification of substituents on etoposide that interact with the enzyme. Biochemistry 46(28):8217-25
Andrews CA, et al.  (2006) A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin. Genes Dev 20(9):1162-74
Barker CR, et al.  (2006) The identification and characterisation of a functional interaction between arginyl-tRNA-protein transferase and topoisomerase II. Biochem Biophys Res Commun 342(2):596-604
Malik M, et al.  (2006) Roles of nonhomologous end-joining pathways in surviving topoisomerase II-mediated DNA damage. Mol Cancer Ther 5(6):1405-14
Mouchel NA and Jenkins JR  (2006) The identification of a functional interaction between PKC and topoisomerase II. FEBS Lett 580(1):51-7
Mueller-Planitz F and Herschlag D  (2006) Interdomain communication in DNA topoisomerase II. DNA binding and enzyme activation. J Biol Chem 281(33):23395-404