RNR1/YER070W Literature Guide Help

Other names published for RNR1: CRT7, RIR1, SDS12, ribonucleotide-diphosphate reductase subunit RNR1, YER070W

RNR1 - Primary Literature (53)

ReferenceOther Genes Addressed
Gupta A, et al.  (2013) Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools. Genetics 193(4):1095-105
Mazumder A, et al.  (2013) Single-cell analysis of ribonucleotide reductase transcriptional and translational response to DNA damage. Mol Cell Biol 33(3):635-42
Weinberger M, et al.  (2013) DNA replication stress-induced loss of reproductive capacity in S. cerevisiae and its inhibition by caloric restriction. Cell Cycle 12(8):1189-200
Ahmad F, et al.  (2012) Role of arginine 293 and glutamine 288 in communication between catalytic and allosteric sites in yeast ribonucleotide reductase. J Mol Biol 419(5):315-29
Patil A, et al.  (2012) Increased tRNA modification and gene-specific codon usage regulate cell cycle progression during the DNA damage response. Cell Cycle 11(19):3656-65
Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
Dyavaiah M, et al.  (2011) Autophagy-Dependent Regulation of the DNA Damage Response Protein Ribonucleotide Reductase 1. Mol Cancer Res 9(4):462-475
Fairman JW, et al.  (2011) Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization. Nat Struct Mol Biol 18(3):316-22
Kumar D, et al.  (2011) Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools. Nucleic Acids Res 39(4):1360-71
Tsaponina O, et al.  (2011) Ixr1 Is Required for the Expression of the Ribonucleotide Reductase Rnr1 and Maintenance of dNTP Pools. PLoS Genet 7(5):e1002061
Andreson BL, et al.  (2010) The ribonucleotide reductase inhibitor, Sml1, is sequentially phosphorylated, ubiquitylated and degraded in response to DNA damage. Nucleic Acids Res 38(19):6490-501
Koren A, et al.  (2010) MRC1-dependent scaling of the budding yeast DNA replication timing program. Genome Res 20(6):781-90
Kumar D, et al.  (2010) Highly mutagenic and severely imbalanced dNTP pools can escape detection by the S-phase checkpoint. Nucleic Acids Res 38(12):3975-83
Mao G and Brody JP  (2010) Reverse Engineering the Yeast RNR1 Transcriptional Control System. PLoS One 5(11):e13895
Di Cecco L, et al.  (2009) Characterisation of gene expression profiles of yeast cells expressing BRCA1 missense variants. Eur J Cancer 45(12):2187-96
Sun D, et al.  (2009) Structure-Based Design, Synthesis, and Evaluation of 2'-(2-Hydroxyethyl)-2'-deoxyadenosine and the 5'-Diphosphate Derivative as Ribonucleotide Reductase Inhibitors. ChemMedChem 4(10):1649-56
Yoo SC, et al.  (2009) Rice Virescent3 and Stripe1 Encoding the Large and Small Subunits of Ribonucleotide Reductase Are Required for Chloroplast Biogenesis during Early Leaf Development. Plant Physiol 150(1):388-401
Cappellacci L, et al.  (2008) Ribose-Modified Purine Nucleosides as Ribonucleotide Reductase Inhibitors. Synthesis, Antitumor Activity, and Molecular Modeling of N(6)-Substituted 3'-C-Methyladenosine Derivatives. J Med Chem 51(14):4260-4269
Begley U, et al.  (2007) Trm9-Catalyzed tRNA Modifications Link Translation to the DNA Damage Response. Mol Cell 28(5):860-870
Camier S, et al.  (2007) Visualization of ribonucleotide reductase catalytic oxidation establishes thioredoxins as its major reductants in yeast. Free Radic Biol Med 42(7):1008-16
Chabes A and Stillman B  (2007) Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 104(4):1183-8
Lebedeva MA and Shadel GS  (2007) Cell cycle- and ribonucleotide reductase-driven changes in mtDNA copy number influence mtDNA Inheritance without compromising mitochondrial gene expression. Cell Cycle 6(16):2048-57
Mao G and Brody JP  (2007) Dynamic SPR monitoring of yeast nuclear protein binding to a cis-regulatory element. Biochem Biophys Res Commun 363(1):153-8
Shen C, et al.  (2007) TOR signaling is a determinant of cell survival in response to DNA damage. Mol Cell Biol 27(20):7007-17
Zhang Z, et al.  (2007) Role of the C terminus of the ribonucleotide reductase large subunit in enzyme regeneration and its inhibition by Sml1. Proc Natl Acad Sci U S A 104(7):2217-22
Benton MG, et al.  (2006) Analyzing the dose-dependence of the Saccharomyces cerevisiae global transcriptional response to methyl methanesulfonate and ionizing radiation. BMC Genomics 7:305
Woolstencroft RN, et al.  (2006) Ccr4 contributes to tolerance of replication stress through control of CRT1 mRNA poly(A) tail length. J Cell Sci 119(Pt 24):5178-92
Xu H, et al.  (2006) Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly. Proc Natl Acad Sci U S A 103(11):4028-33
Xu H, et al.  (2006) Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation. Proc Natl Acad Sci U S A 103(11):4022-7
Carter CD, et al.  (2005) Loss of SOD1 and LYS7 sensitizes Saccharomyces cerevisiae to hydroxyurea and DNA damage agents and downregulates MEC1 pathway effectors. Mol Cell Biol 25(23):10273-85