MEC1/YBR136W Literature Guide Help

Other names published for MEC1: ESR1, SAD3, RAD31, YBR136W

MEC1 - Omics (56)

ReferenceOther Genes Addressed
Foltman M, et al.  (2013) Eukaryotic replisome components cooperate to process histones during chromosome replication. Cell Rep 3(3):892-904
Rodriguez J and Tsukiyama T  (2013) ATR-like kinase Mec1 facilitates both chromatin accessibility at DNA replication forks and replication fork progression during replication stress. Genes Dev 27(1):74-86
Cheung HC, et al.  (2012) An S/T-Q cluster domain census unveils new putative targets under Tel1/Mec1 control. BMC Genomics 13(1):664
Davidson MB, et al.  (2012) Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype. EMBO J 31(4):895-907
De Piccoli G, et al.  (2012) Replisome stability at defective DNA replication forks is independent of S phase checkpoint kinases. Mol Cell 45(5):696-704
Lai AC, et al.  (2012) Predicting kinase substrates using conservation of local motif density. Bioinformatics 28(7):962-9
Liang D, et al.  (2012) Histone dosage regulates DNA damage sensitivity in a checkpoint-independent manner by the homologous recombination pathway. Nucleic Acids Res 40(19):9604-20
Psakhye I and Jentsch S  (2012) Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair. Cell 151(4):807-20
Tittel-Elmer M, et al.  (2012) Cohesin association to replication sites depends on rad50 and promotes fork restart. Mol Cell 48(1):98-108
Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
Feng W, et al.  (2011) Replication stress-induced chromosome breakage is correlated with replication fork progression and is preceded by single-stranded DNA formation. G3 (Bethesda) 1(5):327-35
Kitada T, et al.  (2011) gammaH2A is a component of yeast heterochromatin required for telomere elongation. Cell Cycle 10(2):293-300
Kubota T, et al.  (2011) Quantitative proteomic analysis of chromatin reveals that Ctf18 acts in the DNA replication checkpoint. Mol Cell Proteomics 10(7):M110.005561
Leon Ortiz AM, et al.  (2011) Srs2 overexpression reveals a helicase-independent role at replication forks that requires diverse cell functions. DNA Repair (Amst) 10(5):506-17
Reha-Krantz LJ, et al.  (2011) Drug-sensitive DNA polymerase d reveals a role for mismatch repair in checkpoint activation in yeast. Genetics 189(4):1211-24
Bandyopadhyay S, et al.  (2010) Rewiring of genetic networks in response to DNA damage. Science 330(6009):1385-9
Chen SH, et al.  (2010) A proteome-wide analysis of kinase-substrate network in the DNA damage response. J Biol Chem 285(17):12803-12
Crabbe L, et al.  (2010) Analysis of replication profiles reveals key role of RFC-Ctf18 in yeast replication stress response. Nat Struct Mol Biol 17(11):1391-1397
Jarosz DF and Lindquist S  (2010) Hsp90 and environmental stress transform the adaptive value of natural genetic variation. Science 330(6012):1820-4
Lopez-Mosqueda J, et al.  (2010) Damage-induced phosphorylation of Sld3 is important to block late origin firing. Nature 467(7314):479-83
On T, et al.  (2010) The evolutionary landscape of the chromatin modification machinery reveals lineage specific gains, expansions, and losses. Proteins 78(9):2075-89
Rogers C, et al.  (2010) Connecting mutations of the RNA polymerase II C-terminal domain to complex phenotypic changes using combined gene expression and network analyses. PLoS One 5(6):e11386
Szilard RK, et al.  (2010) Systematic identification of fragile sites via genome-wide location analysis of gamma-H2AX. Nat Struct Mol Biol 17(3):299-305
Theis JF, et al.  (2010) The DNA Damage Response Pathway Contributes to the Stability of Chromosome III Derivatives Lacking Efficient Replicators. PLoS Genet 6(12):e1001227
Karhumaa K, et al.  (2009) Proteome analysis of the xylose-fermenting mutant yeast strain TMB 3400. Yeast 26(7):371-82
Molin C, et al.  (2009) mRNA stability changes precede changes in steady-state mRNA amounts during hyperosmotic stress. RNA 15(4):600-14
Ohuchi T, et al.  (2009) Accumulation of sumoylated Rad52 in checkpoint mutants perturbed in DNA replication. DNA Repair (Amst) 8(6):690-6
Pennaneach V and Kolodner RD  (2009) Stabilization of dicentric translocations through secondary rearrangements mediated by multiple mechanisms in S. cerevisiae. PLoS One 4(7):e6389
Albuquerque CP, et al.  (2008) A multidimensional chromatography technology for in-depth phosphoproteome analysis. Mol Cell Proteomics 7(7):1389-96
Dixon SJ, et al.  (2008) Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes. Proc Natl Acad Sci U S A 105(43):16653-8