Other names published for SIR2: MAR1, YDL042C
SIR2 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Cross-species Expression
- Disease Gene Related
- Fungal Related Genes/Proteins
- Non-Fungal Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
SIR2 - Non-Fungal Related Genes/Proteins (123)
| Reference | Other Genes Addressed |
|---|---|
| Tsai YC, et al. (2012) Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. Mol Cell Proteomics 11(2):M111.015156 | |
| Tung SY, et al. (2012) Chromatin affinity-precipitation using a small metabolic molecule: its application to analysis of O-acetyl-ADP-ribose. Cell Mol Life Sci 69(4):641-50 | |
| Zhang A, et al. (2012) Genetic analysis of SIRT1 gene promoter in sporadic Parkinson's disease. Biochem Biophys Res Commun 422(4):693-6 | |
| Alba Sorolla M, et al. (2011) Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation. Arch Biochem Biophys 510(1):27-34 | |
| Burnett C, et al. (2011) Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature 477(7365):482-5 | |
| Cohen-Kfir E, et al. (2011) Sirt1 is a regulator of bone mass and a repressor of Sost encoding for sclerostin, a bone formation inhibitor. Endocrinology 152(12):4514-24 | |
| Freitag M, et al. (2011) Synthesis and biological activity of splitomicin analogs targeted at human NAD(+)-dependent histone deacetylases (sirtuins). Bioorg Med Chem 19(12):3669-77 | |
| Polo SE and Jackson SP (2011) Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev 25(5):409-33 | |
| Schug TT and Li X (2011) Sirtuin 1 in lipid metabolism and obesity. Ann Med 43(3):198-211 | |
| Tennen RI and Chua KF (2011) Chromatin regulation and genome maintenance by mammalian SIRT6. Trends Biochem Sci 36(1):39-46 | |
| Xiang L, et al. (2011) Anti-aging effects of phloridzin, an apple polyphenol, on yeast via the SOD and Sir2 genes. Biosci Biotechnol Biochem 75(5):854-8 | |
| Yamamoto T and Sadoshima J (2011) Protection of the heart against ischemia/reperfusion by silent information regulator 1. Trends Cardiovasc Med 21(1):27-32 | |
| Aljada A, et al. (2010) Sirtuin-targeting drugs: Mechanisms of action and potential therapeutic applications. Curr Opin Investig Drugs 11(10):1158-68 | |
| Balcerczyk A and Pirola L (2010) Therapeutic potential of activators and inhibitors of sirtuins. Biofactors 36(5):383-93 | |
| Baur JA (2010) Resveratrol, sirtuins, and the promise of a DR mimetic. Mech Ageing Dev 131(4):261-9 | |
| Duan W and Ross CA (2010) Potential therapeutic targets for neurodegenerative diseases: lessons learned from calorie restriction. Curr Drug Targets 11(10):1281-92 | |
| Joyce EF and McKim KS (2010) Chromosome axis defects induce a checkpoint-mediated delay and interchromosomal effect on crossing over during Drosophila meiosis.LID - e1001059 [pii] PLoS Genet 6(8) | |
| On T, et al. (2010) The evolutionary landscape of the chromatin modification machinery reveals lineage specific gains, expansions, and losses. Proteins 78(9):2075-89 | |
| Schemies J, et al. (2010) NAD(+) -dependent histone deacetylases (sirtuins) as novel therapeutic targets. Med Res Rev 30(6):861-89 | |
| Zhang J, et al. (2010) Systems biology of energy homeostasis in yeast. Curr Opin Microbiol 13(3):382-8 | |
| Blander G, et al. (2009) SIRT1 promotes differentiation of normal human keratinocytes. J Invest Dermatol 129(1):41-9 | |
| Du J, et al. (2009) Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD. Biochemistry 48(13):2878-90 | |
| Kong XX, et al. (2009) Function of SIRT1 in physiology. Biochemistry (Mosc) 74(7):703-8 | |
| Yu J and Auwerx J (2009) The role of sirtuins in the control of metabolic homeostasis. Ann N Y Acad Sci 1173 Suppl 1:E10-9 | |
| Greiss S, et al. (2008) C. elegans SIR-2.1 translocation is linked to a proapoptotic pathway parallel to cep-1/p53 during DNA damage-induced apoptosis. Genes Dev 22(20):2831-42 | |
| Griswold AJ, et al. (2008) Sir2 mediates apoptosis through JNK-dependent pathways in Drosophila. Proc Natl Acad Sci U S A 105(25):8673-8 | |
| Hasegawa K and Yoshikawa K (2008) Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons. J Neurosci 28(35):8772-84 | |
| Lain S, et al. (2008) Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell 13(5):454-63 | |
| Li Y, et al. (2008) SirT1 Inhibition Reduces IGF-I/IRS-2/Ras/ERK1/2 Signaling and Protects Neurons. Cell Metab 8(1):38-48 | |
| Michishita E, et al. (2008) SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature 452(7186):492-6 | |




