PRP8/YHR165C Literature Guide Help

Other names published for PRP8: DBF3, DNA39, RNA8, SLT21, USA2, YHR165C

PRP8 - Non-Fungal Related Genes/Proteins (30)

ReferenceOther Genes Addressed
Dlakic M and Mushegian A  (2011) Prp8, the pivotal protein of the spliceosomal catalytic center, evolved from a retroelement-encoded reverse transcriptase. RNA 17(5):799-808
Fabrizio P, et al.  (2009) The Evolutionarily Conserved Core Design of the Catalytic Activation Step of the Yeast Spliceosome. Mol Cell 36(4):593-608
Pena V, et al.  (2008) Structure and function of an RNase H domain at the heart of the spliceosome. EMBO J 27(21):2929-40
Ritchie DB, et al.  (2008) Structural elucidation of a PRP8 core domain from the heart of the spliceosome. Nat Struct Mol Biol 15(11):1199-205
Sperling J, et al.  (2008) Structure and function of the Pre-mRNA splicing machine. Structure 16(11):1605-15
Boon KL, et al.  (2007) prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast. Nat Struct Mol Biol 14(11):1077-83
Pena V, et al.  (2007) Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa. Mol Cell 25(4):615-24
Bellare P, et al.  (2006) Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p. RNA 12(2):292-302
Kofler M, et al.  (2005) GYF domain proteomics reveals interaction sites in known and novel target proteins. Mol Cell Proteomics 4(11):1797-811
Neubauer G  (2005) The analysis of multiprotein complexes: the yeast and the human spliceosome as case studies. Methods Enzymol 405:236-63
Jurica MS, et al.  (2002) Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. RNA 8(4):426-39
Maytal-Kivity V, et al.  (2002) MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function. BMC Biochem 3():28
Mougin A, et al.  (2002) Direct probing of RNA structure and RNA-protein interactions in purified HeLa cell's and yeast spliceosomal U4/U6.U5 tri-snRNP particles. J Mol Biol 317(5):631-49
Fast NM and Doolittle WF  (1999) Trichomonas vaginalis possesses a gene encoding the essential spliceosomal component, PRP8. Mol Biochem Parasitol 99(2):275-8
McDonald WH, et al.  (1999) Myb-related fission yeast cdc5p is a component of a 40S snRNP-containing complex and is essential for pre-mRNA splicing. Mol Cell Biol 19(8):5352-62
Ponting CP, et al.  (1999) Eukaryotic signalling domain homologues in archaea and bacteria. Ancient ancestry and horizontal gene transfer. J Mol Biol 289(4):729-45
Reyes JL, et al.  (1999) The C-terminal region of hPrp8 interacts with the conserved GU dinucleotide at the 5' splice site. RNA 5(2):167-79
Siatecka M, et al.  (1999) Functional interactions of Prp8 with both splice sites at the spliceosomal catalytic center. Genes Dev 13(15):1983-93
Stevens SW and Abelson J  (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc Natl Acad Sci U S A 96(13):7226-31
Achsel T, et al.  (1998) The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein. Mol Cell Biol 18(11):6756-66
Machesky LM, et al.  (1998) The helC gene encodes a putative DEAD-box RNA helicase required for development in Dictyostelium discoideum. Curr Biol 8(10):607-10
Lucke S, et al.  (1997) Trans mRNA splicing in trypanosomes: cloning and analysis of a PRP8-homologous gene from Trypanosoma brucei provides evidence for a U5-analogous RNP. EMBO J 16(14):4433-40
Lauber J, et al.  (1996) The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases. EMBO J 15(15):4001-15
Hodges PE, et al.  (1995) Extraordinary sequence conservation of the PRP8 splicing factor. Yeast 11(4):337-42
Shea JE, et al.  (1994) The budding yeast U5 snRNP Prp8 is a highly conserved protein which links RNA splicing with cell cycle progression. Nucleic Acids Res 22(25):5555-64
Staknis D and Reed R  (1994) Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assembly. Mol Cell Biol 14(5):2994-3005
Kulesza H, et al.  (1993) Detection of a plant protein analogous to the yeast spliceosomal protein, PRP8. FEBS Lett 318(1):4-6
Garcia-Blanco MA, et al.  (1990) A mammalian protein of 220 kDa binds pre-mRNAs in the spliceosome: a potential homologue of the yeast PRP8 protein. Proc Natl Acad Sci U S A 87(8):3082-6
Anderson GJ, et al.  (1989) Conservation between yeast and man of a protein associated with U5 small nuclear ribonucleoprotein. Nature 342(6251):819-21
Pinto AL and Steitz JA  (1989) The mammalian analogue of the yeast PRP8 splicing protein is present in the U4/5/6 small nuclear ribonucleoprotein particle and the spliceosome. Proc Natl Acad Sci U S A 86(22):8742-6