GCN2/YDR283C Literature Guide Help

Other names published for GCN2: AAS1, NDR2, AAS102, YDR283C

GCN2 - Non-Fungal Related Genes/Proteins (29)

ReferenceOther Genes Addressed
Li MW, et al.  (2013) The GCN2 homologue in Arabidopsis thaliana interacts with uncharged tRNA and uses Arabidopsis eIF2a molecules as direct substrates. Plant Biol (Stuttg) 15(1):13-8
Kimpe M, et al.  (2012) Pkh1 interacts with and phosphorylates components of the yeast Gcn2/eIF2a system. Biochem Biophys Res Commun 419(1):89-94
Armache JP, et al.  (2010) Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution. Proc Natl Acad Sci U S A 107(46):19748-19753
Gallego O, et al.  (2010) A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae. Mol Syst Biol 6():430
Dang Do AN, et al.  (2009) eIF2{alpha} kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver. Physiol Genomics 38(3):328-41
Madeo F, et al.  (2009) Phylogenetic conservation of the preapoptotic calreticulin exposure pathway from yeast to mammals. Cell Cycle 8(4):639-42
Guo F and Cavener DR  (2007) The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid. Cell Metab 5(2):103-14
Dever TE and Hinnebusch AG  (2005) GCN2 Whets the Appetite for Amino Acids. Mol Cell 18(2):141-2
Padyana AK, et al.  (2005) Structural basis for autoinhibition and mutational activation of eukaryotic initiation factor 2alpha protein kinase GCN2. J Biol Chem 280(32):29289-99
Pereira CM, et al.  (2005) IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activation. J Biol Chem 280(31):28316-23
Nameki N, et al.  (2004) Solution structure of the RWD domain of the mouse GCN2 protein. Protein Sci 13(8):2089-100
Cherkasova VA and Hinnebusch AG  (2003) Translational control by TOR and TAP42 through dephosphorylation of eIF2alpha kinase GCN2. Genes Dev 17(7):859-72
Kubota H, et al.  (2003) Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2 alpha kinase GCN2. J Biol Chem 278(23):20457-60
Pomar N, et al.  (2003) Functional characterization of Drosophila melanogaster PERK eukaryotic initiation factor 2alpha (eIF2alpha) kinase. Eur J Biochem 270(2):293-306
Zhang Y, et al.  (2003) Molecular cloning of an arabidopsis homologue of GCN2, a protein kinase involved in co-ordinated response to amino acid starvation. Planta 217(4):668-75
Clemens MJ  (2001) Initiation factor eIF2 alpha phosphorylation in stress responses and apoptosis. Prog Mol Subcell Biol 27():57-89
Chang LY, et al.  (2000) Functional complementation by wheat eIF2alpha in the yeast GCN2-mediated pathway. Biochem Biophys Res Commun 279(2):468-74
Garcia-Barrio M, et al.  (2000) Association of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activation. EMBO J 19(8):1887-99
Sood R, et al.  (2000) A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha. Genetics 154(2):787-801
Berlanga JJ, et al.  (1999) Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase. Eur J Biochem 265(2):754-62
Olsen DS, et al.  (1998) Isolation of the gene encoding the Drosophila melanogaster homolog of the Saccharomyces cerevisiae GCN2 eIF-2alpha kinase. Genetics 149(3):1495-509
Shi Y, et al.  (1998) Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control. Mol Cell Biol 18(12):7499-509
Santoyo J, et al.  (1997) Cloning and characterization of a cDNA encoding a protein synthesis initiation factor-2alpha (eIF-2alpha) kinase from Drosophila melanogaster. Homology To yeast GCN2 protein kinase. J Biol Chem 272(19):12544-50
Taylor DR, et al.  (1996) Autophosphorylation sites participate in the activation of the double-stranded-RNA-activated protein kinase PKR. Mol Cell Biol 16(11):6295-302
Mager WH and De Kruijff AJ  (1995) Stress-induced transcriptional activation. Microbiol Rev 59(3):506-31
Romano PR, et al.  (1995) Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae. Mol Cell Biol 15(1):365-78
Dever TE, et al.  (1993) Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast. Proc Natl Acad Sci U S A 90(10):4616-20
Chong KL, et al.  (1992) Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2. EMBO J 11(4):1553-62
Chen JJ, et al.  (1991) Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase. Proc Natl Acad Sci U S A 88(17):7729-33