VPS34/YLR240W Literature Guide Help

Other names published for VPS34: END12, PEP15, VPL7, VPT29, STT8, VPS7, phosphatidylinositol 3-kinase VPS34, YLR240W

VPS34 - Non-Fungal Related Genes/Proteins (28)

ReferenceOther Genes Addressed
Jaber N, et al.  (2012) Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function. Proc Natl Acad Sci U S A 109(6):2003-8
Couplan E, et al.  (2009) Polyunsaturated fatty acids inhibit PI3K activity in a yeast-based model system. Biotechnol J 4(8):1190-7
Godefroy N, et al.  (2009) Identification of autophagy genes in Ciona intestinalis: A new experimental model to study autophagy mechanism. Autophagy 5(6):805-15
Rigden DJ, et al.  (2009) Autophagy in protists: Examples of secondary loss, lineage-specific innovations, and the conundrum of remodeling a single mitochondrion. Autophagy 5(6):784-94
Backer JM  (2008) The regulation and function of Class III PI3Ks: novel roles for Vps34. Biochem J 410(1):1-17
Schoijet AC, et al.  (2008) A Trypanosoma cruzi Phosphatidylinositol 3-Kinase (TcVps34) Is Involved in Osmoregulation and Receptor-mediated Endocytosis. J Biol Chem 283(46):31541-31550
Meijer WH, et al.  (2007) ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes. Autophagy 3(2):106-16
Yan Y and Backer JM  (2007) Regulation of class III (Vps34) PI3Ks. Biochem Soc Trans 35(Pt 2):239-41
Hall BS, et al.  (2006) TbVps34, the trypanosome orthologue of Vps34, is required for Golgi complex segregation. J Biol Chem 281(37):27600-12
Rodriguez-Escudero I, et al.  (2005) Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast. Biochem J 390(Pt 2):613-23
Gruenberg J and Stenmark H  (2004) The biogenesis of multivesicular endosomes. Nat Rev Mol Cell Biol 5(4):317-23
Xue Y, et al.  (2003) Genetic analysis of the myotubularin family of phosphatases in Caenorhabditis elegans. J Biol Chem 278(36):34380-6
Aoki H, et al.  (2000) Characterization of Ce-atl-1, an ATM-like gene from Caenorhabditis elegans. Mol Gen Genet 264(1-2):119-26
Vessey CJ, et al.  (1999) Genetic disorders associated with cancer predisposition and genomic instability. Prog Nucleic Acid Res Mol Biol 63():189-221
Panaretou C, et al.  (1997) Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex. J Biol Chem 272(4):2477-85
Brown WJ, et al.  (1995) Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells. J Cell Biol 130(4):781-96
Davidson HW  (1995) Wortmannin causes mistargeting of procathepsin D. evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes. J Cell Biol 130(4):797-805
Volinia S, et al.  (1995) A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system. EMBO J 14(14):3339-48
Woscholski R, et al.  (1995) Modulation of the substrate specificity of the mammalian phosphatidylinositol 3-kinase by cholesterol sulfate and sulfatide. Biochemistry 34(36):11489-93
Zhou K, et al.  (1995) A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development. Mol Cell Biol 15(10):5645-56
Kodaki T, et al.  (1994) Mammalian phosphatidylinositol 3'-kinase induces a lethal phenotype on expression in Schizosaccharomyces pombe; comparison with the VPS34 gene product. Eur J Biochem 219(3):775-80
Stephens L, et al.  (1994) Characterization of a phosphatidylinositol-specific phosphoinositide 3-kinase from mammalian cells. Curr Biol 4(3):203-14
Welters P, et al.  (1994) AtVPS34, a phosphatidylinositol 3-kinase of Arabidopsis thaliana, is an essential protein with homology to a calcium-dependent lipid binding domain. Proc Natl Acad Sci U S A 91(24):11398-402
Woscholski R, et al.  (1994) A comparison of demethoxyviridin and wortmannin as inhibitors of phosphatidylinositol 3-kinase. FEBS Lett 342(2):109-14
Fry MJ and Waterfield MD  (1993) Structure and function of phosphatidylinositol 3-kinase: a potential second messenger system involved in growth control. Philos Trans R Soc Lond B Biol Sci 340(1293):337-44
Hu P, et al.  (1993) Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85. Mol Cell Biol 13(12):7677-88
Hiles ID, et al.  (1992) Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit. Cell 70(3):419-29
Auger KR, et al.  (1989) Phosphatidylinositol 3-kinase and its novel product, phosphatidylinositol 3-phosphate, are present in Saccharomyces cerevisiae. J Biol Chem 264(34):20181-4