RAD6/YGL058W Literature Guide Help

Other names published for RAD6: UBC2, PSO8, E2 ubiquitin-conjugating protein RAD6, YGL058W

RAD6 - Non-Fungal Related Genes/Proteins (27)

ReferenceOther Genes Addressed
Shchebet A, et al.  (2012) Phosphorylation by cyclin-dependent kinase-9 controls ubiquitin-conjugating enzyme-2A function. Cell Cycle 11(11):2122-7
Yoon JH, et al.  (2012) Requirement of Rad18 protein for replication through DNA lesions in mouse and human cells. Proc Natl Acad Sci U S A 109(20):7799-804
Liu F and Walters KJ  (2010) Multitasking with ubiquitin through multivalent interactions. Trends Biochem Sci 35(6):352-60
On T, et al.  (2010) The evolutionary landscape of the chromatin modification machinery reveals lineage specific gains, expansions, and losses. Proteins 78(9):2075-89
Tirosh I, et al.  (2010) Chromatin regulators as capacitors of interspecies variations in gene expression. Mol Syst Biol 6():435
Bech-Otschir D, et al.  (2009) Polyubiquitin substrates allosterically activate their own degradation by the 26S proteasome. Nat Struct Mol Biol 16(2):219-25
Kim J and Roeder RG  (2009) Direct Bre1-Paf1 Complex Interactions and RING Finger-independent Bre1-Rad6 Interactions Mediate Histone H2B Ubiquitylation in Yeast. J Biol Chem 284(31):20582-92
Kim J, et al.  (2009) RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell 137(3):459-71
Michelle C, et al.  (2009) What was the set of ubiquitin and ubiquitin-like conjugating enzymes in the eukaryote common ancestor? J Mol Evol 68(6):616-28
Prakash S, et al.  (2009) Substrate selection by the proteasome during degradation of protein complexes. Nat Chem Biol 5(1):29-36
Thorsen M, et al.  (2009) Genetic basis of arsenite and cadmium tolerance in Saccharomyces cerevisiae. BMC Genomics 10:105
Shilatifard A  (2006) Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression. Annu Rev Biochem 75():243-69
Kavakebi P, et al.  (2005) The N-end rule ubiquitin-conjugating enzyme, HR6B, is up-regulated by nerve growth factor and required for neurite outgrowth. Mol Cell Neurosci 29(4):559-68
Crowe E and Candido EP  (2004) Characterization of C. elegans RING finger protein 1, a binding partner of ubiquitin-conjugating enzyme 1. Dev Biol 265(2):446-59
Roest HP, et al.  (2004) The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice. Mol Cell Biol 24(12):5485-95
Sasaki H, et al.  (2004) Decreased Hrad6B expression in lung cancer. Acta Oncol 43(6):585-9
Baarends WM, et al.  (2003) Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase. Mol Cell Biol 23(4):1151-62
Sarcevic B, et al.  (2002) Regulation of the ubiquitin-conjugating enzyme hHR6A by CDK-mediated phosphorylation. EMBO J 21(8):2009-18
Dronkert ML and Kanaar R  (2001) Repair of DNA interstrand cross-links. Mutat Res 486(4):217-47
Xin H, et al.  (2000) The human RAD18 gene product interacts with HHR6A and HHR6B. Nucleic Acids Res 28(14):2847-54
Baarends WM, et al.  (1999) Histone ubiquitination and chromatin remodeling in mouse spermatogenesis. Dev Biol 207(2):322-33
Sonoda H, et al.  (1999) Suppression of oncogenic transformation by hypothemycin associated with accelerated cyclin D1 degradation through ubiquitin-proteasome pathway. Life Sci 65(4):381-94
Ikehata H, et al.  (1997) Incubation at the nonpermissive temperature induces deficiencies in UV resistance and mutagenesis in mouse mutant cells expressing a temperature-sensitive ubiquitin-activating enzyme (E1). Mol Cell Biol 17(3):1484-9
Tam SW, et al.  (1997) Kip1 degradation via the ubiquitin-proteasome pathway. Leukemia 11 Suppl 3():363-6
Zwirn P, et al.  (1997) Arabidopsis thaliana RAD6 homolog AtUBC2 complements UV sensitivity, but not N-end rule degradation deficiency, of Saccharomyces cerevisiae rad6 mutants. Curr Genet 32(5):309-14
Roest HP, et al.  (1996) Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification. Cell 86(5):799-810
Haas AL, et al.  (1991) Ubiquitin conjugation by the yeast RAD6 and CDC34 gene products. Comparison to their putative rabbit homologs, E2(20K) AND E2(32K). J Biol Chem 266(8):5104-12