SIR2/YDL042C Literature Guide Help

Other names published for SIR2: MAR1, YDL042C

SIR2 - Non-Fungal Related Genes/Proteins (123)

ReferenceOther Genes Addressed
Tsai YC, et al.  (2012) Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. Mol Cell Proteomics 11(2):M111.015156
Tung SY, et al.  (2012) Chromatin affinity-precipitation using a small metabolic molecule: its application to analysis of O-acetyl-ADP-ribose. Cell Mol Life Sci 69(4):641-50
Zhang A, et al.  (2012) Genetic analysis of SIRT1 gene promoter in sporadic Parkinson's disease. Biochem Biophys Res Commun 422(4):693-6
Alba Sorolla M, et al.  (2011) Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation. Arch Biochem Biophys 510(1):27-34
Burnett C, et al.  (2011) Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature 477(7365):482-5
Cohen-Kfir E, et al.  (2011) Sirt1 is a regulator of bone mass and a repressor of Sost encoding for sclerostin, a bone formation inhibitor. Endocrinology 152(12):4514-24
Freitag M, et al.  (2011) Synthesis and biological activity of splitomicin analogs targeted at human NAD(+)-dependent histone deacetylases (sirtuins). Bioorg Med Chem 19(12):3669-77
Polo SE and Jackson SP  (2011) Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev 25(5):409-33
Schug TT and Li X  (2011) Sirtuin 1 in lipid metabolism and obesity. Ann Med 43(3):198-211
Tennen RI and Chua KF  (2011) Chromatin regulation and genome maintenance by mammalian SIRT6. Trends Biochem Sci 36(1):39-46
Xiang L, et al.  (2011) Anti-aging effects of phloridzin, an apple polyphenol, on yeast via the SOD and Sir2 genes. Biosci Biotechnol Biochem 75(5):854-8
Yamamoto T and Sadoshima J  (2011) Protection of the heart against ischemia/reperfusion by silent information regulator 1. Trends Cardiovasc Med 21(1):27-32
Aljada A, et al.  (2010) Sirtuin-targeting drugs: Mechanisms of action and potential therapeutic applications. Curr Opin Investig Drugs 11(10):1158-68
Balcerczyk A and Pirola L  (2010) Therapeutic potential of activators and inhibitors of sirtuins. Biofactors 36(5):383-93
Baur JA  (2010) Resveratrol, sirtuins, and the promise of a DR mimetic. Mech Ageing Dev 131(4):261-9
Duan W and Ross CA  (2010) Potential therapeutic targets for neurodegenerative diseases: lessons learned from calorie restriction. Curr Drug Targets 11(10):1281-92
Joyce EF and McKim KS  (2010) Chromosome axis defects induce a checkpoint-mediated delay and interchromosomal effect on crossing over during Drosophila meiosis.LID - e1001059 [pii] PLoS Genet 6(8)
On T, et al.  (2010) The evolutionary landscape of the chromatin modification machinery reveals lineage specific gains, expansions, and losses. Proteins 78(9):2075-89
Schemies J, et al.  (2010) NAD(+) -dependent histone deacetylases (sirtuins) as novel therapeutic targets. Med Res Rev 30(6):861-89
Zhang J, et al.  (2010) Systems biology of energy homeostasis in yeast. Curr Opin Microbiol 13(3):382-8
Blander G, et al.  (2009) SIRT1 promotes differentiation of normal human keratinocytes. J Invest Dermatol 129(1):41-9
Du J, et al.  (2009) Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD. Biochemistry 48(13):2878-90
Kong XX, et al.  (2009) Function of SIRT1 in physiology. Biochemistry (Mosc) 74(7):703-8
Yu J and Auwerx J  (2009) The role of sirtuins in the control of metabolic homeostasis. Ann N Y Acad Sci 1173 Suppl 1:E10-9
Greiss S, et al.  (2008) C. elegans SIR-2.1 translocation is linked to a proapoptotic pathway parallel to cep-1/p53 during DNA damage-induced apoptosis. Genes Dev 22(20):2831-42
Griswold AJ, et al.  (2008) Sir2 mediates apoptosis through JNK-dependent pathways in Drosophila. Proc Natl Acad Sci U S A 105(25):8673-8
Hasegawa K and Yoshikawa K  (2008) Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons. J Neurosci 28(35):8772-84
Lain S, et al.  (2008) Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell 13(5):454-63
Li Y, et al.  (2008) SirT1 Inhibition Reduces IGF-I/IRS-2/Ras/ERK1/2 Signaling and Protects Neurons. Cell Metab 8(1):38-48
Michishita E, et al.  (2008) SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature 452(7186):492-6