ERG11/YHR007C Literature Guide Help

Other names published for ERG11: CYP51, sterol 14-demethylase, YHR007C

ERG11 - Non-Fungal Related Genes/Proteins (17)

ReferenceOther Genes Addressed
Hoepfner D, et al.  (2012) An integrated approach for identification and target validation of antifungal compounds active against Erg11p. Antimicrob Agents Chemother 56(8):4233-40
Parker JE, et al.  (2008) Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus. Antimicrob Agents Chemother 52(10):3597-603
Tu BP and McKnight SL  (2007) The yeast metabolic cycle: insights into the life of a eukaryotic cell. Cold Spring Harb Symp Quant Biol 72:339-43
Chau AS, et al.  (2006) Molecular Basis for Enhanced Activity of Posaconazole against Absidia corymbifera and Rhizopus oryzae. Antimicrob Agents Chemother 50(11):3917-9
Buckner FS, et al.  (2003) Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase. Mol Biochem Parasitol 132(2):75-81
Lamb DC, et al.  (2000) Differential inhibition of human CYP3A4 and Candida albicans CYP51 with azole antifungal agents. Chem Biol Interact 125(3):165-75
Cabello-Hurtado F, et al.  (1999) Optimized expression and catalytic properties of a wheat obtusifoliol 14alpha-demethylase (CYP51) expressed in yeast. Complementation of erg11Delta yeast mutants by plant CYP51. Eur J Biochem 262(2):435-46
Lamb DC, et al.  (1999) Characteristics of the heterologously expressed human lanosterol 14alpha-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human and Candida albicans CYP51 with azole antifungal agents. Yeast 15(9):755-63
Lewis DF, et al.  (1999) Molecular modelling of lanosterol 14 alpha-demethylase (CYP51) from Saccharomyces cerevisiae via homology with CYP102, a unique bacterial cytochrome P450 isoform: quantitative structure-activity relationships (QSARs) within two related series of antifungal azole derivatives. J Enzyme Inhib 14(3):175-92
Venkateswarlu K, et al.  (1998) The N-terminal membrane domain of yeast NADPH-cytochrome P450 (CYP) oxidoreductase is not required for catalytic activity in sterol biosynthesis or in reconstitution of CYP activity. J Biol Chem 273(8):4492-6
Cabello-Hurtado F, et al.  (1997) Cloning and functional expression in yeast of a cDNA coding for an obtusifoliol 14alpha-demethylase (CYP51) in wheat. Biochem Biophys Res Commun 230(2):381-5
Aoyama Y, et al.  (1996) Sterol 14-demethylase P450 (P45014DM*) is one of the most ancient and conserved P450 species. J Biochem 119(5):926-33
van Nistelrooy JG, et al.  (1996) Isolation and molecular characterisation of the gene encoding eburicol 14 alpha-demethylase (cYP51) from Penicillium italicum. Mol Gen Genet 250(6):725-33
Boscott PE and Grant GH  (1994) Modeling cytochrome P450 14 alpha demethylase (Candida albicans) from P450cam. J Mol Graph 12(3):185-92, 195
Aoyama Y and Yoshida Y  (1991) Different substrate specificities of lanosterol 14a-demethylase (P-45014DM) of Saccharomyces cerevisiae and rat liver for 24-methylene-24,25-dihydrolanosterol and 24,25-dihydrolanosterol. Biochem Biophys Res Commun 178(3):1064-71
Kalb VF, et al.  (1987) Primary structure of the P450 lanosterol demethylase gene from Saccharomyces cerevisiae. DNA 6(6):529-37
Mitropoulos KA, et al.  (1976) Lanosterol 14alpha-demethylase. Similarity of the enzyme system from yeast and rat liver. Steroids 27(6):821-9