Other names published for MEC1: ESR1, SAD3, RAD31, YBR136W
MEC1 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Cross-species Expression
- Disease Gene Related
- Fungal Related Genes/Proteins
- Non-Fungal Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
MEC1 - Non-Fungal Related Genes/Proteins (35)
| Reference | Other Genes Addressed |
|---|---|
| Polo SE and Jackson SP (2011) Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev 25(5):409-33 | |
| On T, et al. (2010) The evolutionary landscape of the chromatin modification machinery reveals lineage specific gains, expansions, and losses. Proteins 78(9):2075-89 | |
| Friedel AM, et al. (2009) ATR/Mec1: coordinating fork stability and repair. Curr Opin Cell Biol 21(2):237-44 | |
| Lisby M and Rothstein R (2009) Choreography of recombination proteins during the DNA damage response. DNA Repair (Amst) 8(9):1068-76 | |
| Anderson CM and Blackburn EH (2008) Mec1 function in the DNA damage response does not require its interaction with Tel2. Cell Cycle 7(23):3695-8 | |
| Mordes DA and Cortez D (2008) Activation of ATR and related PIKKs. Cell Cycle 7(18):2809-12 | |
| Krishnan V, et al. (2007) A novel cell cycle inhibitor stalls replication forks and activates S phase checkpoint. Cell Cycle 6(13):1621-30 | |
| McSherry TD, et al. (2007) Non-catalytic function for ATR in the checkpoint response. Cell Cycle 6(16):2019-30 | |
| Miranda-Saavedra D and Barton GJ (2007) Classification and functional annotation of eukaryotic protein kinases. Proteins 68(4):893-914 | |
| Garber PM, et al. (2005) Damage in transition. Trends Biochem Sci 30(2):63-6 | |
| Bartrand AJ, et al. (2004) DNA stimulates Mec1-mediated phosphorylation of replication protein A. J Biol Chem 279(25):26762-7 | |
| Clifford DM, et al. (2004) The meiosis-specific protein kinase Ime2 directs phosphorylation of replication protein A. J Biol Chem 279(7):6163-70 | |
| Lupardus PJ and Cimprich KA (2004) Checkpoint adaptation; molecular mechanisms uncovered. Cell 117(5):555-6 | |
| Rouse J (2004) Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage. EMBO J 23(5):1188-97 | |
| Shroff R, et al. (2004) Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break. Curr Biol 14(19):1703-11 | |
| Clarke DJ, et al. (2003) S-phase checkpoint controls mitosis via an APC-independent Cdc20p function. Nat Cell Biol 5(10):928-35 | |
| Cobb JA, et al. (2003) DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. EMBO J 22(16):4325-36 | |
| O'Driscoll M, et al. (2003) A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome. Nat Genet 33(4):497-501 | |
| Zou L and Elledge SJ (2003) Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300(5625):1542-8 | |
| Cha RS and Kleckner N (2002) ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones. Science 297(5581):602-6 | |
| Rouse J and Jackson SP (2002) Interfaces between the detection, signaling, and repair of DNA damage. Science 297(5581):547-51 | |
| Brush GS, et al. (2001) Replication protein A is sequentially phosphorylated during meiosis. Nucleic Acids Res 29(23):4808-17 | |
| Dronkert ML and Kanaar R (2001) Repair of DNA interstrand cross-links. Mutat Res 486(4):217-47 | |
| Latif C, et al. (2001) Ensuring the stability of the genome: DNA damage checkpoints. ScientificWorldJournal 1():684-702 | |
| Meier B and Ahmed S (2001) Checkpoints: chromosome pairing takes an unexpected twist. Curr Biol 11(21):R865-8 | |
| Wang Y, et al. (2001) Antitumor drug adozelesin differentially affects active and silent origins of DNA replication in yeast checkpoint kinase mutants. Cancer Res 61(9):3787-94 | |
| Aoki H, et al. (2000) Characterization of Ce-atl-1, an ATM-like gene from Caenorhabditis elegans. Mol Gen Genet 264(1-2):119-26 | |
| Garcia V, et al. (2000) An ATM homologue from Arabidopsis thaliana: complete genomic organisation and expression analysis. Nucleic Acids Res 28(8):1692-9 | |
| Mallory JC and Petes TD (2000) Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase. Proc Natl Acad Sci U S A 97(25):13749-54 | |
| Mills KD, et al. (1999) MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks. Cell 97(5):609-20 |




