MEC1/YBR136W Literature Guide Help

Other names published for MEC1: ESR1, SAD3, RAD31, YBR136W

MEC1 - Non-Fungal Related Genes/Proteins (35)

ReferenceOther Genes Addressed
Polo SE and Jackson SP  (2011) Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev 25(5):409-33
On T, et al.  (2010) The evolutionary landscape of the chromatin modification machinery reveals lineage specific gains, expansions, and losses. Proteins 78(9):2075-89
Friedel AM, et al.  (2009) ATR/Mec1: coordinating fork stability and repair. Curr Opin Cell Biol 21(2):237-44
Lisby M and Rothstein R  (2009) Choreography of recombination proteins during the DNA damage response. DNA Repair (Amst) 8(9):1068-76
Anderson CM and Blackburn EH  (2008) Mec1 function in the DNA damage response does not require its interaction with Tel2. Cell Cycle 7(23):3695-8
Mordes DA and Cortez D  (2008) Activation of ATR and related PIKKs. Cell Cycle 7(18):2809-12
Krishnan V, et al.  (2007) A novel cell cycle inhibitor stalls replication forks and activates S phase checkpoint. Cell Cycle 6(13):1621-30
McSherry TD, et al.  (2007) Non-catalytic function for ATR in the checkpoint response. Cell Cycle 6(16):2019-30
Miranda-Saavedra D and Barton GJ  (2007) Classification and functional annotation of eukaryotic protein kinases. Proteins 68(4):893-914
Garber PM, et al.  (2005) Damage in transition. Trends Biochem Sci 30(2):63-6
Bartrand AJ, et al.  (2004) DNA stimulates Mec1-mediated phosphorylation of replication protein A. J Biol Chem 279(25):26762-7
Clifford DM, et al.  (2004) The meiosis-specific protein kinase Ime2 directs phosphorylation of replication protein A. J Biol Chem 279(7):6163-70
Lupardus PJ and Cimprich KA  (2004) Checkpoint adaptation; molecular mechanisms uncovered. Cell 117(5):555-6
Rouse J  (2004) Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage. EMBO J 23(5):1188-97
Shroff R, et al.  (2004) Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break. Curr Biol 14(19):1703-11
Clarke DJ, et al.  (2003) S-phase checkpoint controls mitosis via an APC-independent Cdc20p function. Nat Cell Biol 5(10):928-35
Cobb JA, et al.  (2003) DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. EMBO J 22(16):4325-36
O'Driscoll M, et al.  (2003) A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome. Nat Genet 33(4):497-501
Zou L and Elledge SJ  (2003) Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300(5625):1542-8
Cha RS and Kleckner N  (2002) ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones. Science 297(5581):602-6
Rouse J and Jackson SP  (2002) Interfaces between the detection, signaling, and repair of DNA damage. Science 297(5581):547-51
Brush GS, et al.  (2001) Replication protein A is sequentially phosphorylated during meiosis. Nucleic Acids Res 29(23):4808-17
Dronkert ML and Kanaar R  (2001) Repair of DNA interstrand cross-links. Mutat Res 486(4):217-47
Latif C, et al.  (2001) Ensuring the stability of the genome: DNA damage checkpoints. ScientificWorldJournal 1():684-702
Meier B and Ahmed S  (2001) Checkpoints: chromosome pairing takes an unexpected twist. Curr Biol 11(21):R865-8
Wang Y, et al.  (2001) Antitumor drug adozelesin differentially affects active and silent origins of DNA replication in yeast checkpoint kinase mutants. Cancer Res 61(9):3787-94
Aoki H, et al.  (2000) Characterization of Ce-atl-1, an ATM-like gene from Caenorhabditis elegans. Mol Gen Genet 264(1-2):119-26
Garcia V, et al.  (2000) An ATM homologue from Arabidopsis thaliana: complete genomic organisation and expression analysis. Nucleic Acids Res 28(8):1692-9
Mallory JC and Petes TD  (2000) Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase. Proc Natl Acad Sci U S A 97(25):13749-54
Mills KD, et al.  (1999) MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks. Cell 97(5):609-20