TIM50/YPL063W Literature Guide Help

Other names published for TIM50: YPL063W

TIM50 Literature Curation Summary

Curated References for TIM50: 70

Date of last curation: 2013-05-23

ReferenceOther Genes Addressed
Dudek J, et al.  (2013) Mitochondrial protein import: Common principles and physiological networks. Biochim Biophys Acta 1833(2):274-85
Lytovchenko O, et al.  (2013) Signal recognition initiates reorganization of the presequence translocase during protein import. EMBO J 32(6):886-98
Paul P, et al.  (2013) The protein translocation systems in plants -- composition and variability on the example of Solanum lycopersicum. BMC Genomics 14(1):189
Fox TD  (2012) Mitochondrial protein synthesis, import, and assembly. Genetics 192(4):1203-34
Hughes AL and Gottschling DE  (2012) An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast. Nature 492(7428):261-5
Neupert W  (2012) A mitochondrial odyssey. Annu Rev Biochem 81():1-33
Reinhold R, et al.  (2012) The channel-forming Sym1 protein is transported by the TIM23 complex in a presequence-independent manner. Mol Cell Biol 32(24):5009-21
Gebert N, et al.  (2011) Mitochondrial protein import machineries and lipids: a functional connection. Biochim Biophys Acta 1808(3):1002-11
Liu Z, et al.  (2011) Tracing the evolution of the mitochondrial protein import machinery. Comput Biol Chem 35(6):336-40
Marom M, et al.  (2011) Direct interaction of mitochondrial targeting presequences with purified components of the TIM23 protein complex. J Biol Chem 286(51):43809-15
Qian X, et al.  (2011) Structural basis for the function of Tim50 in the mitochondrial presequence translocase. J Mol Biol 411(3):513-9
Schulz C, et al.  (2011) Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex. J Cell Biol 195(4):643-56
Shiota T, et al.  (2011) In vivo protein-interaction mapping of a mitochondrial translocator protein Tom22 at work. Proc Natl Acad Sci U S A 108(37):15179-83
Yogev O, et al.  (2011) Fumarase: a paradigm of dual targeting and dual localized functions. FEBS J 278(22):4230-42
Chacinska A, et al.  (2010) Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting. Mol Cell Biol 30(1):307-18
Endo T and Yamano K  (2010) Transport of proteins across or into the mitochondrial outer membrane. Biochim Biophys Acta 1803(6):706-14
Lithgow T and Schneider A  (2010) Evolution of macromolecular import pathways in mitochondria, hydrogenosomes and mitosomes. Philos Trans R Soc Lond B Biol Sci 365(1541):799-817
Sinha D, et al.  (2010) Role of Magmas in protein transport and human mitochondria biogenesis. Hum Mol Genet 19(7):1248-62
van der Laan M, et al.  (2010) On the mechanism of preprotein import by the mitochondrial presequence translocase. Biochim Biophys Acta 1803(6):732-9
Gevorkyan-Airapetov L, et al.  (2009) Interaction of Tim23 with Tim50 Is Essential for Protein Translocation by the Mitochondrial TIM23 Complex. J Biol Chem 284(8):4865-72
Mokranjac D and Neupert W  (2009) Thirty years of protein translocation into mitochondria: unexpectedly complex and still puzzling. Biochim Biophys Acta 1793(1):33-41
Mokranjac D, et al.  (2009) Role of Tim50 in the transfer of precursor proteins from the outer to the inner membrane of mitochondria. Mol Biol Cell 20(5):1400-7
Szklarczyk R and Huynen MA  (2009) Expansion of the human mitochondrial proteome by intra- and inter-compartmental protein duplication. Genome Biol 10(11):R135
Tamura Y, et al.  (2009) Tim23-Tim50 pair coordinates functions of translocators and motor proteins in mitochondrial protein import. J Cell Biol 184(1):129-41
Tamura Y, et al.  (2009) Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria. J Cell Biol 185(6):1029-45
Wagner K, et al.  (2009) Protein transport machineries for precursor translocation across the inner mitochondrial membrane. Biochim Biophys Acta 1793(1):52-9
Alder NN, et al.  (2008) Quaternary structure of the mitochondrial TIM23 complex reveals dynamic association between Tim23p and other subunits. Mol Biol Cell 19(1):159-70
Becker D, et al.  (2008) In vitro analysis of the mitochondrial preprotein import machinery using recombinant precursor polypeptides. Methods Mol Biol 457():59-83
Bolender N, et al.  (2008) Multiple pathways for sorting mitochondrial precursor proteins. EMBO Rep 9(1):42-9
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8