LCB1/YMR296C Literature Guide Help

Other names published for LCB1: END8, TSC2, serine C-palmitoyltransferase LCB1, YMR296C

LCB1 Literature Curation Summary

Curated References for LCB1: 104

Date of last curation: 2013-04-25

ReferenceOther Genes Addressed
Hanada K, et al.  (1997) A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis. J Biol Chem 272(51):32108-14
Jenkins GM, et al.  (1997) Involvement of yeast sphingolipids in the heat stress response of Saccharomyces cerevisiae. J Biol Chem 272(51):32566-72
Sutterlin C, et al.  (1997) Specific requirements for the ER to Golgi transport of GPI-anchored proteins in yeast. J Cell Sci 110 ( Pt 21):2703-14
Weiss B and Stoffel W  (1997) Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis. Eur J Biochem 249(1):239-47
Munn AL and Riezman H  (1994) Endocytosis is required for the growth of vacuolar H(+)-ATPase-defective yeast: identification of six new END genes. J Cell Biol 127(2):373-86
Nagiec MM, et al.  (1994) The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis. Proc Natl Acad Sci U S A 91(17):7899-902
Zhao C, et al.  (1994) Suppressors of the Ca(2+)-sensitive yeast mutant (csg2) identify genes involved in sphingolipid biosynthesis. Cloning and characterization of SCS1, a gene required for serine palmitoyltransferase activity. J Biol Chem 269(34):21480-8
Nagiec MM, et al.  (1993) A suppressor gene that enables Saccharomyces cerevisiae to grow without making sphingolipids encodes a protein that resembles an Escherichia coli fatty acyltransferase. J Biol Chem 268(29):22156-63
Horn WS, et al.  (1992) Sphingofungins E and F: novel serinepalmitoyl transferase inhibitors from Paecilomyces variotii. J Antibiot (Tokyo) 45(10):1692-6
Pinto WJ, et al.  (1992) Characterization of enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity. J Bacteriol 174(8):2575-81
Pinto WJ, et al.  (1992) Sphingolipid long-chain-base auxotrophs of Saccharomyces cerevisiae: genetics, physiology, and a method for their selection. J Bacteriol 174(8):2565-74
Zweerink MM, et al.  (1992) Characterization of a novel, potent, and specific inhibitor of serine palmitoyltransferase. J Biol Chem 267(35):25032-8
Buede R, et al.  (1991) Cloning and characterization of LCB1, a Saccharomyces gene required for biosynthesis of the long-chain base component of sphingolipids. J Bacteriol 173(14):4325-32
Dickson RC, et al.  (1990) Isolation of mutant Saccharomyces cerevisiae strains that survive without sphingolipids. Mol Cell Biol 10(5):2176-81