YFH1/YDL120W Literature Guide Help

Other names published for YFH1: YDL120W

YFH1 - Mutants/Phenotypes (80)

ReferenceOther Genes Addressed
Bulteau AL, et al.  (2012) Changes in mitochondrial glutathione levels and protein thiol oxidation in ?yfh1 yeast cells and the lymphoblasts of patients with Friedreich's ataxia. Biochim Biophys Acta 1822(2):212-25
Cotticelli MG, et al.  (2012) Primary and secondary drug screening assays for Friedreich ataxia. J Biomol Screen 17(3):303-13
Lefevre S, et al.  (2012) Apn1 AP-endonuclease is essential for the repair of oxidatively damaged DNA bases in yeast frataxin-deficient cells. Hum Mol Genet 21(18):4060-72
Lefevre S, et al.  (2012) Oxidative stress induces mitochondrial fragmentation in frataxin-deficient cells. Biochem Biophys Res Commun 418(2):336-41
Lefevre S, et al.  (2012) The yeast metacaspase is implicated in oxidative stress response in frataxin-deficient cells. FEBS Lett 586(2):143-8
Li L, et al.  (2012) A role for iron-sulfur clusters in the regulation of transcription factor Yap5-dependent high iron transcriptional responses in yeast. J Biol Chem 287(42):35709-21
Marobbio CM, et al.  (2012) Rapamycin reduces oxidative stress in frataxin-deficient yeast cells. Mitochondrion 12(1):156-61
Nishida K and Silver PA  (2012) Induction of biogenic magnetization and redox control by a component of the target of rapamycin complex 1 signaling pathway. PLoS Biol 10(2):e1001269
Sliwa D, et al.  (2012) Inactivation of mitochondrial aspartate aminotransferase contributes to the respiratory deficit of yeast frataxin-deficient cells. Biochem J 441(3):945-53
Sutak R, et al.  (2012) Human mitochondrial ferritin improves respiratory function in yeast mutants deficient in iron-sulfur cluster biogenesis, but is not a functional homologue of yeast frataxin. Microbiologyopen 1(2):95-104
Yoon H, et al.  (2012) Mutation in the Fe-S scaffold protein Isu bypasses frataxin deletion. Biochem J 441(1):473-80
Bedekovics T, et al.  (2011) Leucine biosynthesis regulates cytoplasmic iron-sulfur enzyme biogenesis in an Atm1p-independent manner. J Biol Chem 286(47):40878-88
Castells-Roca L, et al.  (2011) The oxidative stress response in yeast cells involves changes in the stability of Aft1 regulon mRNAs. Mol Microbiol 81(1):232-48
Seguin A, et al.  (2011) Co-precipitation of Phosphate and Iron Limits Mitochondrial Phosphate Availability in Saccharomyces cerevisiae Lacking the Yeast Frataxin Homologue (YFH1). J Biol Chem 286(8):6071-9
Soderberg CA, et al.  (2011) Oligomerization propensity and flexibility of yeast frataxin studied by X-ray crystallography and small-angle X-ray scattering. J Mol Biol 414(5):783-97
Vaubel RA, et al.  (2011) Mutations in the dimer interface of dihydrolipoamide dehydrogenase promote site-specific oxidative damages in yeast and human cells. J Biol Chem 286(46):40232-45
Yoon H, et al.  (2011) Rim2, a pyrimidine nucleotide exchanger, is needed for iron utilization in mitochondria. Biochem J 440(1):137-46
Correia AR, et al.  (2010) Iron-binding activity in yeast frataxin entails a trade off with stability in the alpha1/beta1 acidic ridge region. Biochem J 426(2):197-203
Gonzalez-Cabo P, et al.  (2010) Flavin adenine dinucleotide rescues the phenotype of frataxin deficiency. PLoS One 5(1):e8872
Irazusta V, et al.  (2010) Yeast frataxin mutants display decreased superoxide dismutase activity crucial to promote protein oxidative damage. Free Radic Biol Med 48(3):411-420
Kim JH, et al.  (2010) Dynamics of protein damage in yeast frataxin mutant exposed to oxidative stress. OMICS 14(6):689-99
Kim JH, et al.  (2010) Oxidative stress studies in yeast with a frataxin mutant: a proteomics perspective. J Proteome Res 9(2):730-6
Leidgens S, et al.  (2010) Frataxin interacts with Isu1 through a conserved tryptophan in its {beta}-sheet. Hum Mol Genet 19(2):276-86
Moreno-Cermeno A, et al.  (2010) Frataxin Depletion in Yeast Triggers Up-regulation of Iron Transport Systems before Affecting Iron-Sulfur Enzyme Activities. J Biol Chem 285(53):41653-64
Seguin A, et al.  (2010) Evidence that yeast frataxin is not an iron storage protein in vivo. Biochim Biophys Acta 1802(6):531-538
Li H, et al.  (2009) Oligomeric yeast frataxin drives assembly of core machinery for mitochondrial iron-sulfur cluster synthesis. J Biol Chem 284(33):21971-80
Naranuntarat A, et al.  (2009) The interaction of mitochondrial iron with manganese superoxide dismutase. J Biol Chem 284(34):22633-40
Seguin A, et al.  (2009) Overexpression of the yeast frataxin homolog (Yfh1): Contrasting effects on iron-sulfur cluster assembly, heme synthesis and resistance to oxidative stress. Mitochondrion 9(2):130-138
Andrew AJ, et al.  (2008) Posttranslational regulation of the scaffold for Fe-S cluster biogenesis, Isu. Mol Biol Cell 19(12):5259-66
Auchere F, et al.  (2008) Glutathione-dependent redox status of frataxin-deficient cells in a yeast model of Friedreich's ataxia. Hum Mol Genet 17(18):2790-802