VDE Literature Guide Help

Other names published for VDE: YDL184w-a, VDE1, YDL185W2, PI-SceI

VDE - Mutants/Phenotypes (30)

ReferenceOther Genes Addressed
Hiraishi H, et al.  (2008) Transcriptional regulation of Saccharomyces cerevisiae CYS3 encoding cystathionine gamma-lyase. Curr Genet 53(4):225-34
Brenzel S, et al.  (2006) Engineering artificially split inteins for applications in protein chemistry: biochemical characterization of the split Ssp DnaB intein and comparison to the split Sce VMA intein. Biochemistry 45(6):1571-8
Fukuda T, et al.  (2006) Investigation of the mechanism of meiotic DNA cleavage by VMA1-derived endonuclease uncovers a meiotic alteration in chromatin structure around the target site. Eukaryot Cell 5(6):981-90
Srikanth CV, et al.  (2005) Multiple cis-regulatory elements and the yeast sulphur regulatory network are required for the regulation of the yeast glutathione transporter, Hgt1p. Curr Genet 47(6):345-58
Mizutani R, et al.  (2004) Protein splicing of yeast VMA1-derived endonuclease via thiazolidine intermediates. J Synchrotron Radiat 11(Pt 1):109-12
Noel AJ, et al.  (2004) DNA recognition by the homing endonuclease PI-SceI involves a divalent metal ion cofactor-induced conformational change. J Biol Chem 279(8):6794-804
Gimble FS, et al.  (2003) Assessing the plasticity of DNA target site recognition of the PI-SceI homing endonuclease using a bacterial two-hybrid selection system. J Mol Biol 334(5):993-1008
Miyake T, et al.  (2003) Involvement of the VDE homing endonuclease and rapamycin in regulation of the Saccharomyces cerevisiae GSH11 gene encoding the high affinity glutathione transporter. J Biol Chem 278(41):39632-6
Nagai Y, et al.  (2003) Karyopherin-mediated nuclear import of the homing endonuclease VMA1-derived endonuclease is required for self-propagation of the coding region. Mol Cell Biol 23(5):1726-36
Mizutani R, et al.  (2002) Protein-splicing reaction via a thiazolidine intermediate: crystal structure of the VMA1-derived endonuclease bearing the N and C-terminal propeptides. J Mol Biol 316(4):919-29
Posey KL and Gimble FS  (2002) Insertion of a reversible redox switch into a rare-cutting DNA endonuclease. Biochemistry 41(7):2184-90
Gimble FS  (2001) Degeneration of a homing endonuclease and its target sequence in a wild yeast strain. Nucleic Acids Res 29(20):4215-23
Christ F, et al.  (2000) A model for the PI-SceIxDNA complex based on multiple base and phosphate backbone-specific photocross-links. J Mol Biol 300(4):867-75
Hu D, et al.  (2000) Probing the structure of the PI-SceI-DNA complex by affinity cleavage and affinity photocross-linking. J Biol Chem 275(4):2705-12
Poland BW, et al.  (2000) Structural insights into the protein splicing mechanism of PI-SceI. J Biol Chem 275(22):16408-13
Wende W, et al.  (2000) [Analysis of binding and cleavage of DNA by the gene conversion PI-SCEI endonuclease using site-directed mutagenesis] Mol Biol (Mosk) 34(6):1054-64
Hu D, et al.  (1999) Mapping of a DNA binding region of the PI-sceI homing endonuclease by affinity cleavage and alanine-scanning mutagenesis. Biochemistry 38(39):12621-8
Pingoud V, et al.  (1999) Photocross-linking of the homing endonuclease PI-SceI to its recognition sequence. J Biol Chem 274(15):10235-43
Chong S, et al.  (1998) Modulation of protein splicing of the Saccharomyces cerevisiae vacuolar membrane ATPase intein. J Biol Chem 273(17):10567-77
Gimble FS, et al.  (1998) Identification of Lys-403 in the PI-SceI homing endonuclease as part of a symmetric catalytic center. J Biol Chem 273(46):30524-9
Pingoud V, et al.  (1998) Structural and functional analysis of the homing endonuclease PI-sceI by limited proteolytic cleavage and molecular cloning of partial digestion products. Biochemistry 37(22):8233-43
Chong S and Xu MQ  (1997) Protein splicing of the Saccharomyces cerevisiae VMA intein without the endonuclease motifs. J Biol Chem 272(25):15587-90
Kawasaki M, et al.  (1997) Identification of three core regions essential for protein splicing of the yeast Vma1 protozyme. A random mutagenesis study of the entire Vma1-derived endonuclease sequence. J Biol Chem 272(25):15668-74
Nogami S, et al.  (1997) Probing novel elements for protein splicing in the yeast Vma1 protozyme: a study of replacement mutagenesis and intragenic suppression. Genetics 147(1):73-85
Chong S, et al.  (1996) Protein splicing involving the Saccharomyces cerevisiae VMA intein. The steps in the splicing pathway, side reactions leading to protein cleavage, and establishment of an in vitro splicing system. J Biol Chem 271(36):22159-68
Gimble FS and Wang J  (1996) Substrate recognition and induced DNA distortion by the PI-SceI endonuclease, an enzyme generated by protein splicing. J Mol Biol 263(2):163-80
Wende W, et al.  (1996) Binding, bending and cleavage of DNA substrates by the homing endonuclease Pl-SceI. Nucleic Acids Res 24(21):4123-32
Gimble FS and Stephens BW  (1995) Substitutions in conserved dodecapeptide motifs that uncouple the DNA binding and DNA cleavage activities of PI-SceI endonuclease. J Biol Chem 270(11):5849-56
Cooper AA, et al.  (1993) Protein splicing of the yeast TFP1 intervening protein sequence: a model for self-excision. EMBO J 12(6):2575-83
Hirata R and Anraku Y  (1992) Mutations at the putative junction sites of the yeast VMA1 protein, the catalytic subunit of the vacuolar membrane H(+)-ATPase, inhibit its processing by protein splicing. Biochem Biophys Res Commun 188(1):40-7