UBR1/YGR184C Literature Guide Help

Other names published for UBR1: PTR1, E3 ubiquitin-protein ligase UBR1, YGR184C

UBR1 - Mutants/Phenotypes (41)

Results: 1 - 30 of 41 records
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ReferenceOther Genes Addressed
Hjerpe R, et al.  (2012) Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes. Biochem J 441(3):927-36
Khmelinskii A, et al.  (2012) Tandem fluorescent protein timers for in vivo analysis of protein dynamics.LID - 10.1038/nbt.2281 [doi] Nat Biotechnol ()
Khosrow-Khavar F, et al.  (2012) The yeast ubr1 ubiquitin ligase participates in a prominent pathway that targets cytosolic thermosensitive mutants for degradation. G3 (Bethesda) 2(5):619-28
Theodoraki MA, et al.  (2012) A network of ubiquitin ligases is important for the dynamics of misfolded protein aggregates in yeast. J Biol Chem 287(28):23911-22
Hwang CS, et al.  (2011) Ubiquitin Ligases of the N-End Rule Pathway: Assessment of Mutations in UBR1 That Cause the Johanson-Blizzard Syndrome. PLoS One 6(9):e24925
Latham JA, et al.  (2011) Chromatin Signaling to Kinetochores: Transregulation of Dam1 Methylation by Histone H2B Ubiquitination. Cell 146(5):709-19
Andreson BL, et al.  (2010) The ribonucleotide reductase inhibitor, Sml1, is sequentially phosphorylated, ubiquitylated and degraded in response to DNA damage. Nucleic Acids Res 38(19):6490-501
Heck JW, et al.  (2010) Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1. Proc Natl Acad Sci U S A 107(3):1106-11
Hwang CS, et al.  (2010) N-terminal acetylation of cellular proteins creates specific degradation signals. Science 327(5968):973-7
Nillegoda NB, et al.  (2010) Ubr1 and ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins. Mol Biol Cell 21(13):2102-16
Pfirrmann T, et al.  (2010) The prodomain of ssy5 protease controls receptor-activated proteolysis of transcription factor stp1. Mol Cell Biol 30(13):3299-309
Prasad R, et al.  (2010) A nucleus-based quality control mechanism for cytosolic proteins. Mol Biol Cell 21(13):2117-27
Putnam CD, et al.  (2010) Post-replication repair suppresses duplication-mediated genome instability. PLoS Genet 6():e1000933
Torres EM, et al.  (2010) Identification of aneuploidy-tolerating mutations. Cell 143(1):71-83
Hwang CS, et al.  (2009) Two proteolytic pathways regulate DNA repair by cotargeting the Mgt1 alkylguanine transferase. Proc Natl Acad Sci U S A 106(7):2142-7
Liu C, et al.  (2009) A genome-wide synthetic dosage lethality screen reveals multiple pathways that require the functioning of ubiquitin-binding proteins Rad23 and Dsk2. BMC Biol 7(1):75
Taxis C, et al.  (2009) Efficient protein depletion by genetically controlled deprotection of a dormant N-degron. Mol Syst Biol 5:267
Eisele F and Wolf DH  (2008) Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1. FEBS Lett 582(30):4143-6
Hwang CS and Varshavsky A  (2008) Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway. Proc Natl Acad Sci U S A 105(49):19188-93
Xia Z, et al.  (2008) Amino Acids Induce Peptide Uptake via Accelerated Degradation of CUP9, the Transcriptional Repressor of the PTR2 Peptide Transporter. J Biol Chem 283(43):28958-68
Xia Z, et al.  (2008) Substrate-binding Sites of UBR1, the Ubiquitin Ligase of the N-end Rule Pathway. J Biol Chem 283(35):24011-28
Cai H, et al.  (2006) Genomewide Screen Reveals a Wide Regulatory Network for Di/Tripeptide Utilization in Saccharomyces cerevisiae. Genetics 172(3):1459-76
Freimoser FM, et al.  (2006) Systematic screening of polyphosphate (poly P) levels in yeast mutant cells reveals strong interdependence with primary metabolism. Genome Biol 7(11):R109
Gambus A, et al.  (2006) GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks. Nat Cell Biol 8(4):358-66
Game JC, et al.  (2006) The RAD6/BRE1 histone modification pathway in Saccharomyces confers radiation resistance through a RAD51-dependent process that is independent of RAD18. Genetics 173(4):1951-68
Hanna J, et al.  (2006) Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation. Cell 127(1):99-111
Ju D and Xie Y  (2006) A synthetic defect in protein degradation caused by loss of Ufd4 and Rad23. Biochem Biophys Res Commun 341(2):648-52
Stagoj MN, et al.  (2005) Fluorescence based assay of GAL system in yeast Saccharomyces cerevisiae. FEMS Microbiol Lett 244(1):105-10
Kushner DB, et al.  (2003) Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Proc Natl Acad Sci U S A 100(26):15764-9
Rao H, et al.  (2001) Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability. Nature 410(6831):955-9
Results: 1 - 30 of 41 records
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