TUB2/YFL037W Literature Guide Help

Other names published for TUB2: ARM10, SHE8, YFL037W

TUB2 - Mutants/Phenotypes (83)

ReferenceOther Genes Addressed
Ayaz P, et al.  (2012) A TOG:alphabeta-tubulin complex structure reveals conformation-based mechanisms for a microtubule polymerase. Science 337(6096):857-60
Bock LJ, et al.  (2012) Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore. Nat Cell Biol 14(6):614-24
Cederquist GY, et al.  (2012) An inherited TUBB2B mutation alters a kinesin-binding site and causes polymicrogyria, CFEOM and axon dysinnervation. Hum Mol Genet 21(26):5484-99
Das L, et al.  (2012) Rationalization of paclitaxel insensitivity of yeast ss-tubulin and human ssIII-tubulin isotype using principal component analysis. BMC Res Notes 5(1):395
Entwistle RA, et al.  (2012) Differentiating between models of epothilone binding to microtubules using tubulin mutagenesis, cytotoxicity, and molecular modeling. ChemMedChem 7(9):1580-6
Erlemann S, et al.  (2012) An extended gamma-tubulin ring functions as a stable platform in microtubule nucleation. J Cell Biol 197(1):59-74
Ten Hoopen R, et al.  (2012) Mechanism for astral microtubule capture by cortical Bud6p priming spindle polarity in S. cerevisiae. Curr Biol 22(12):1075-83
Johnson V, et al.  (2011) Design, overexpression, and purification of polymerization-blocked yeast a?-tubulin mutants. Biochemistry 50(40):8636-44
Caudron F, et al.  (2010) Mutation of Ser172 in Yeast beta Tubulin Induces Defects in Microtubule Dynamics and Cell Division. PLoS One 5(10):e13553
Uchimura S, et al.  (2010) Key residues on microtubule responsible for activation of kinesin ATPase. EMBO J 29(7):1167-75
Anders KR, et al.  (2009) A strategy for constructing aneuploid yeast strains by transient nondisjunction of a target chromosome. BMC Genet 10:36
Keyes BE and Burke DJ  (2009) Irc15 Is a microtubule-associated protein that regulates microtubule dynamics in Saccharomyces cerevisiae. Curr Biol 19(6):472-8
Ungar L, et al.  (2009) A genome-wide screen for essential yeast genes that affect telomere length maintenance. Nucleic Acids Res 37(12):3840-9
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Entwistle RA, et al.  (2008) The paclitaxel site in tubulin probed by site-directed mutagenesis of Saccharomyces cerevisiae beta-tubulin. FEBS Lett 582(16):2467-70
He XC, et al.  (2008) Molecular cloning, expression profiling, and yeast complementation of 19 beta-tubulin cDNAs from developing cotton ovules. J Exp Bot 59(10):2687-95
Niu W, et al.  (2008) Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae. PLoS Genet 4(7):e1000120
Winefield RD, et al.  (2008) Differences in Paclitaxel and docetaxel interactions with tubulin detected by mutagenesis of yeast tubulin. ChemMedChem 3(12):1844-7
Kim C, et al.  (2007) TagSmart: analysis and visualization for yeast mutant fitness data measured by tag microarrays. BMC Bioinformatics 8:128
Hastie CJ, et al.  (2006) The Saccharomyces cerevisiae orthologue of the human protein phosphatase 4 core regulatory subunit R2 confers resistance to the anticancer drug cisplatin. FEBS J 273(14):3322-34
Huang B and Huffaker TC  (2006) Dynamic microtubules are essential for efficient chromosome capture and biorientation in S. cerevisiae. J Cell Biol 175(1):17-23
Pearson CG, et al.  (2006) Measuring nanometer scale gradients in spindle microtubule dynamics using model convolution microscopy. Mol Biol Cell 17(9):4069-79
Uchimura S, et al.  (2006) Identification of a strong binding site for kinesin on the microtubule using mutant analysis of tubulin. EMBO J 25(24):5932-41
Dorn JF, et al.  (2005) Yeast kinetochore microtubule dynamics analyzed by high-resolution three-dimensional microscopy. Biophys J 89(4):2835-54
Foland TB, et al.  (2005) Paclitaxel-induced microtubule stabilization causes mitotic block and apoptotic-like cell death in a paclitaxel-sensitive strain of Saccharomyces cerevisiae. Yeast 22(12):971-8
Andresen M, et al.  (2004) Short tetracysteine tags to beta-tubulin demonstrate the Significance of small labels for live cell imaging. Mol Biol Cell 15(12):5616-22
Huisman SM, et al.  (2004) Differential contribution of Bud6p and Kar9p to microtubule capture and spindle orientation in S. cerevisiae. J Cell Biol 167(2):231-44
You L, et al.  (2004) Model for the yeast cofactor A-beta-tubulin complex based on computational docking and mutagensis. J Mol Biol 341(5):1343-54
Gupta ML Jr, et al.  (2003) Understanding tubulin-Taxol interactions: mutations that impart Taxol binding to yeast tubulin. Proc Natl Acad Sci U S A 100(11):6394-7
Lila T, et al.  (2003) Molecular basis for fungal selectivity of novel antimitotic compounds. Antimicrob Agents Chemother 47(7):2273-82