TPI1/YDR050C Literature Guide Help

Other names published for TPI1: triose-phosphate isomerase TPI1, YDR050C

TPI1 - Mutants/Phenotypes (38)

ReferenceOther Genes Addressed
Hernandez-Santoyo A, et al.  (2012) Effects of a buried cysteine-to-serine mutation on yeast triosephosphate isomerase structure and stability. Int J Mol Sci 13(8):10010-21
Sullivan BJ, et al.  (2012) Stabilizing proteins from sequence statistics: the interplay of conservation and correlation in triosephosphate isomerase stability. J Mol Biol 420(4-5):384-99
Varela C, et al.  (2012) Evaluation of gene modification strategies for the development of low-alcohol-wine yeasts. Appl Environ Microbiol 78(17):6068-77
Cruces-Angeles ME, et al.  (2011) Thermodynamic and kinetic destabilization of triosephosphate isomerase resulting from the mutation of conserved and non-conserved cysteines. Protein Pept Lett 18(12):1290-8
Kruger A, et al.  (2011) The pentose phosphate pathway is a metabolic redox sensor and regulates transcription during the antioxidant response. Antioxid Redox Signal 15(2):311-24
Rachfall N, et al.  (2011) 5'TRU: identification and analysis of translationally regulative 5'untranslated regions in amino acid starved yeast cells. Mol Cell Proteomics 10(6):M110.003350
Fendt SM, et al.  (2010) Tradeoff between enzyme and metabolite efficiency maintains metabolic homeostasis upon perturbations in enzyme capacity. Mol Syst Biol 6():356
Go MK, et al.  (2010) Rescue of K12G Triosephosphate Isomerase by Ammonium Cations: The Reaction of an Enzyme in Pieces. J Am Chem Soc 132(38):13525-32
Go MK, et al.  (2010) Role of Lys-12 in catalysis by triosephosphate isomerase: a two-part substrate approach. Biochemistry 49(25):5377-89
Matsufuji Y, et al.  (2010) Transcription factor Stb5p is essential for acetaldehyde tolerance in Saccharomyces cerevisiae. J Basic Microbiol 50(5):494-8
Ralser M, et al.  (2009) Interfering with Glycolysis Causes Sir2-Dependent Hyper-Recombination of Saccharomyces cerevisiae Plasmids. PLoS ONE 4(4):e5376
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Jung JY, et al.  (2008) Enhanced Production of 1,2-Propanediol by tpi1 Deletion in Saccharomyces cerevisiae. J Microbiol Biotechnol 18(11):1797-802
Peimbert M, et al.  (2008) Hydrophobic repacking of the dimer interface of triosephosphate isomerase by in silico design and directed evolution. Biochemistry 47(20):5556-64
Reyes-Lopez CA, et al.  (2008) The conserved salt bridge linking two C-terminal beta/alpha units in homodimeric triosephosphate isomerase determines the folding rate of the monomer. Proteins 72(3):972-9
Westfall PJ, et al.  (2008) Stress resistance and signal fidelity independent of nuclear MAPK function. Proc Natl Acad Sci U S A 105(34):12212-7
Cordier H, et al.  (2007) A metabolic and genomic study of engineered Saccharomyces cerevisiae strains for high glycerol production. Metab Eng 9(4):364-78
Kleijn RJ, et al.  (2007) Metabolic flux analysis of a glycerol-overproducing Saccharomyces cerevisiae strain based on GC-MS, LC-MS and NMR-derived C-labelling data. FEMS Yeast Res 7(2):216-31
Rozovsky S and McDermott AE  (2007) Substrate product equilibrium on a reversible enzyme, triosephosphate isomerase. Proc Natl Acad Sci U S A 104(7):2080-5
Yongguang Z, et al.  (2007) Deletion of the CgTPI Gene Encoding Triose Phosphate Isomerase of Candida glycerinogenes Inhibits the Biosynthesis of Glycerol. Curr Microbiol 55(2):147-151
Massi F, et al.  (2006) Solution NMR and computer simulation studies of active site loop motion in triosephosphate isomerase. Biochemistry 45(36):10787-94
Shi Y, et al.  (2005) Genetic perturbation of glycolysis results in inhibition of de novo inositol biosynthesis. J Biol Chem 280(51):41805-10
Gonzalez-Mondragon E, et al.  (2004) Conserved cysteine 126 in triosephosphate isomerase is required not for enzymatic activity but for proper folding and stability. Biochemistry 43(11):3255-63
Desamero R, et al.  (2003) Active site loop motion in triosephosphate isomerase: T-jump relaxation spectroscopy of thermal activation. Biochemistry 42(10):2941-51
Capitanio D, et al.  (2002) Effects of the loss of triose phosphate isomerase activity on carbon metabolism in Kluyveromyces lactis. Res Microbiol 153(9):593-8
Overkamp KM, et al.  (2002) Metabolic engineering of glycerol production in Saccharomyces cerevisiae. Appl Environ Microbiol 68(6):2814-21
Steinmetz LM, et al.  (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
Compagno C, et al.  (2001) Alterations of the glucose metabolism in a triose phosphate isomerase-negative Saccharomyces cerevisiae mutant. Yeast 18(7):663-70
Merico A, et al.  (2001) Isolation and sequence analysis of the gene encoding triose phosphate isomerase from Zygosaccharomyces bailii. Yeast 18(9):775-80
Compagno C, et al.  (1999) Isolation, nucleotide sequence, and physiological relevance of the gene encoding triose phosphate isomerase from Kluyveromyces lactis. Appl Environ Microbiol 65(9):4216-9