TOR2/YKL203C Literature Guide Help

Other names published for TOR2: DRR2, YKL203C

TOR2 - Mutants/Phenotypes (60)

ReferenceOther Genes Addressed
Cardon CM, et al.  (2012) PAS Kinase Promotes Cell Survival and Growth Through Activation of Rho1. Sci Signal 5(209):ra9
Liu Q, et al.  (2012) Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiae. ACS Chem Biol 7(6):982-7
Michaillat L, et al.  (2012) Cell-free reconstitution of vacuole membrane fragmentation reveals regulation of vacuole size and number by TORC1. Mol Biol Cell 23(5):881-95
Pagan-Mercado G, et al.  (2012) Functional and genetic interactions of TOR in the budding yeast Saccharomyces cerevisiae with myosin type II-deficiency (myo1Delta). BMC Cell Biol 13(1):13
Pracheil T, et al.  (2012) TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae. Genetics 190(4):1325-39
Hardt M, et al.  (2011) Activating mutations of TOR (target of rapamycin). Genes Cells 16(2):141-51
Ramachandran V and Herman PK  (2011) Antagonistic Interactions Between the cAMP-Dependent Protein Kinase and Tor Signaling Pathways Modulate Cell Growth in Saccharomyces cerevisiae. Genetics 187(2):441-54
Roelants FM, et al.  (2011) Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108(48):19222-7
Sadeh A, et al.  (2011) Fine-tuning of the Msn2/4-mediated yeast stress responses as revealed by systematic deletion of Msn2/4 partners. Mol Biol Cell 22(17):3127-38
Ungar L, et al.  (2011) Tor complex 1 controls telomere length by affecting the level of Ku. Curr Biol 21(24):2115-20
Voordeckers K, et al.  (2011) Yeast 3-phosphoinositide-dependent protein kinase-1 (PDK1) orthologs Pkh1-3 differentially regulate phosphorylation of protein kinase A (PKA) and the protein kinase B (PKB)/S6K ortholog Sch9. J Biol Chem 286(25):22017-27
Limson MV and Sweder KS  (2010) Rapamycin inhibits yeast nucleotide excision repair independently of tor kinases. Toxicol Sci 113(1):77-84
Robbins N, et al.  (2010) Metabolic control of antifungal drug resistance. Fungal Genet Biol 47(2):81-93
Roelants FM, et al.  (2010) A protein kinase network regulates the function of aminophospholipid flippases. Proc Natl Acad Sci U S A 107(1):34-9
Soulard A, et al.  (2010) The Rapamycin-sensitive Phosphoproteome Reveals That TOR Controls Protein Kinase A Toward Some But Not All Substrates. Mol Biol Cell 21(19):3475-86
Sturgill TW and Hall MN  (2009) Activating mutations in TOR are in similar structures as oncogenic mutations in PI3KCalpha. ACS Chem Biol 4(12):999-1015
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Hoon S, et al.  (2008) An integrated platform of genomic assays reveals small-molecule bioactivities. Nat Chem Biol 4(8):498-506
Nakashima A, et al.  (2008) The yeast Tor signaling pathway is involved in G2/M transition via polo-kinase. PLoS ONE 3(5):e2223
Schoner D, et al.  (2008) Annotating novel genes by integrating synthetic lethals and genomic information. BMC Syst Biol 2:3
Smets B, et al.  (2008) Genome-wide expression analysis reveals TORC1-dependent and -independent functions of Sch9. FEMS Yeast Res 8(8):1276-88
Zurita-Martinez SA, et al.  (2007) Efficient Tor signaling requires a functional class C Vps protein complex in Saccharomyces cerevisiae. Genetics 176(4):2139-50
Escusa S, et al.  (2006) Proteasome- and SCF-dependent degradation of yeast adenine deaminase upon transition from proliferation to quiescence requires a new F-box protein named Saf1p. Mol Microbiol 60(4):1014-25
Mulet JM, et al.  (2006) Mutual antagonism of target of rapamycin and calcineurin signaling. J Biol Chem 281(44):33000-7
Tabuchi M, et al.  (2006) The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation. Mol Cell Biol 26(15):5861-75
Davierwala AP, et al.  (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52
Fadri M, et al.  (2005) The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5-bisphosphate and TORC2. Mol Biol Cell 16(4):1883-900
Kabir MA, et al.  (2005) Physiological effects of unassembled chaperonin Cct subunits in the yeast Saccharomyces cerevisiae. Yeast 22(3):219-39
Kamada Y, et al.  (2005) Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization. Mol Cell Biol 25(16):7239-48
Rodriguez-Escudero I, et al.  (2005) Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast. Biochem J 390(Pt 2):613-23