Other names published for TOP1: MAK1, MAK17, DNA topoisomerase 1, YOL006C
TOP1 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
TOP1 - Mutants/Phenotypes (87)
| Reference | Other Genes Addressed |
|---|---|
| Douglas AC, et al. (2012) Functional analysis with a barcoder yeast gene overexpression system. G3 (Bethesda) 2(10):1279-89 | |
| Garcia-Rubio ML and Aguilera A (2012) Topological constraints impair RNA polymerase II transcription and causes instability of plasmid-borne convergent genes. Nucleic Acids Res 40(3):1050-64 | |
| Joshi RS, et al. (2012) Topoisomerase II is required for the production of long Pol II gene transcripts in yeast. Nucleic Acids Res 40(16):7907-15 | |
| French SL, et al. (2011) Distinguishing the Roles of Topoisomerases I and II in Relief of Transcription-Induced Torsional Stress in Yeast rRNA Genes. Mol Cell Biol 31(3):482-94 | |
| Kegel A, et al. (2011) Chromosome length influences replication-induced topological stress. Nature 471(7338):392-6 | |
| Kim N and Jinks-Robertson S (2011) Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast. DNA Repair (Amst) 10(9):953-60 | |
| Kim N, et al. (2011) Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I. Science 332(6037):1561-4 | |
| Lippert MJ, et al. (2011) Role for topoisomerase 1 in transcription-associated mutagenesis in yeast. Proc Natl Acad Sci U S A 108(2):698-703 | |
| Reid RJ, et al. (2011) Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Genome Res 21(3):477-86 | |
| Sperling AS, et al. (2011) Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase I to enhance recruitment of RNA Pol II in budding yeast. Proc Natl Acad Sci U S A 108(31):12693-8 | |
| Sukhanova MV, et al. (2011) Ddc1 checkpoint protein and DNA polymerase ? interact with nick-containing DNA repair intermediate in cell free extracts of Saccharomyces cerevisiae. DNA Repair (Amst) 10(8):815-25 | |
| Takahashi T, et al. (2011) Topoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108(2):692-7 | |
| Bermudez I, et al. (2010) A method for genome-wide analysis of DNA helical tension by means of psoralen-DNA photobinding. Nucleic Acids Res 38(19):e182 | |
| El Hage A, et al. (2010) Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis. Genes Dev 24(14):1546-58 | |
| Joshi RS, et al. (2010) Positional dependence of transcriptional inhibition by DNA torsional stress in yeast chromosomes. EMBO J 29(4):740-8 | |
| Larson ME, et al. (2010) Uncovering chromatin's contribution to the mitotic spindle: Applications of computational and polymer models. Biochimie 92(12):1741-8 | |
| Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 | |
| Lotito L, et al. (2009) A specific transcriptional response of yeast cells to camptothecin dependent on the Swi4 and Mbp1 factors. Eur J Pharmacol 603(1-3):29-36 | |
| Roca J (2009) Two-dimensional agarose gel electrophoresis of DNA topoisomers. Methods Mol Biol 582():27-37 | |
| Xiong L, et al. (2009) Deficient SUMO attachment to Flp recombinase leads to homologous recombination-dependent hyperamplification of the yeast 2 microm circle plasmid. Mol Biol Cell 20(4):1241-51 | |
| de la Loza MC and Wellinger RE (2009) A novel approach for organelle-specific DNA damage targeting reveals different susceptibility of mitochondrial DNA to the anticancer drugs camptothecin and topotecan. Nucleic Acids Res 37(4):e26 | |
| Andersen MP, et al. (2008) A Genetic Screen for Increased Loss of Heterozygosity in Saccharomyces cerevisiae. Genetics 179(3):1179-95 | |
| Hontz RD, et al. (2008) Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30. Mol Cell Biol 28(21):6709-19 | |
| Lotito L, et al. (2008) Global transcription regulation by DNA topoisomerase I in exponentially growing Saccharomyces cerevisiae cells: activation of telomere-proximal genes by TOP1 deletion. J Mol Biol 377(2):311-22 | |
| Palle K, et al. (2008) Disulfide Cross-links Reveal Conserved Features of DNA Topoisomerase I Architecture and a Role for the N Terminus in Clamp Closure. J Biol Chem 283(41):27767-75 | |
| Reid RJ, et al. (2008) Chromosome-Scale Genetic Mapping Using a Set of 16 Conditionally Stable Saccharomyces cerevisiae Chromosomes. Genetics 180(4):1799-808 | |
| Takahashi Y and Strunnikov A (2008) In vivo modeling of polysumoylation uncovers targeting of Topoisomerase II to the nucleolus via optimal level of SUMO modification. Chromosoma 117(2):189-98 | |
| Takahashi Y, et al. (2008) Cooperation of sumoylated chromosomal proteins in rDNA maintenance. PLoS Genet 4(10):e1000215 | |
| Weinstein J and Rothstein R (2008) The genetic consequences of ablating helicase activity and the Top3 interaction domain of Sgs1. DNA Repair (Amst) 7(4):558-71 | |
| van der Merwe M and Bjornsti MA (2008) Mutation of gly721 alters DNA topoisomerase I active site architecture and sensitivity to camptothecin. J Biol Chem 283(6):3305-15 | |




