TIM50/YPL063W Literature Guide Help

Other names published for TIM50: YPL063W

TIM50 - Mutants/Phenotypes (14)

ReferenceOther Genes Addressed
Reinhold R, et al.  (2012) The channel-forming Sym1 protein is transported by the TIM23 complex in a presequence-independent manner. Mol Cell Biol 32(24):5009-21
Qian X, et al.  (2011) Structural basis for the function of Tim50 in the mitochondrial presequence translocase. J Mol Biol 411(3):513-9
Schulz C, et al.  (2011) Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex. J Cell Biol 195(4):643-56
Mokranjac D, et al.  (2009) Role of Tim50 in the transfer of precursor proteins from the outer to the inner membrane of mitochondria. Mol Biol Cell 20(5):1400-7
Tamura Y, et al.  (2009) Tim23-Tim50 pair coordinates functions of translocators and motor proteins in mitochondrial protein import. J Cell Biol 184(1):129-41
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Meinecke M, et al.  (2006) Tim50 maintains the permeability barrier of the mitochondrial inner membrane. Science 312(5779):1523-6
van der Laan M, et al.  (2006) A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr Biol 16(22):2271-6
Chacinska A, et al.  (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29
Davierwala AP, et al.  (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52
Yamano K, et al.  (2005) The phosphate carrier has an ability to be sorted to either the TIM22 pathway or the TIM23 pathway for its import into yeast mitochondria. J Biol Chem 280(11):10011-7
Geissler A, et al.  (2002) The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel. Cell 111(4):507-18
Yamamoto H, et al.  (2002) Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes. Cell 111(4):519-28
Stevenson LF, et al.  (2001) A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Proc Natl Acad Sci U S A 98(7):3946-51