THR1/YHR025W Literature Guide Help

Other names published for THR1: homoserine kinase, YHR025W

THR1 - Mutants/Phenotypes (24)

ReferenceOther Genes Addressed
Short MK, et al.  (2012) The yeast magmas ortholog pam16 has an essential function in fermentative growth that involves sphingolipid metabolism. PLoS One 7(7):e39428
Suzuki T, et al.  (2012) Lactic-acid stress causes vacuolar fragmentation and impairs intracellular amino-acid homeostasis in Saccharomyces cerevisiae. J Biosci Bioeng 113(4):421-30
Daugeron MC, et al.  (2011) Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs. Nucleic Acids Res 39(14):6148-60
Gresham D, et al.  (2011) System-Level Analysis of Genes and Functions Affecting Survival During Nutrient Starvation in Saccharomyces cerevisiae. Genetics 187(1):299-317
Sershen CL, et al.  (2011) Superhelical duplex destabilization and the recombination position effect. PLoS One 6(6):e20798
Uluisik I, et al.  (2011) Genome-wide identification of genes that play a role in boron stress response in yeast. Genomics 97(2):106-11
Kingsbury JM and McCusker JH  (2010) Fungal homoserine kinase (thr1Delta) mutants are attenuated in virulence and die rapidly upon threonine starvation and serum incubation. Eukaryot Cell 9(5):729-37
Kingsbury JM and McCusker JH  (2010) Homoserine toxicity in Saccharomyces cerevisiae and Candida albicans homoserine kinase (thr1Delta) mutants. Eukaryot Cell 9(5):717-28
Ottosson LG, et al.  (2010) Sulfate Assimilation Mediates Tellurite Reduction and Toxicity in Saccharomyces cerevisiae. Eukaryot Cell 9(10):1635-1647
Saint-Marc C, et al.  (2009) Phenotypic consequences of purine nucleotide imbalance in Saccharomyces cerevisiae. Genetics 183(2):529-38, 1SI-7SI
Singh I, et al.  (2009) Stringent mating-type-regulated auxotrophy increases the accuracy of systematic genetic interaction screens with Saccharomyces cerevisiae mutant arrays. Genetics 181(1):289-300
Matsufuji Y, et al.  (2008) Acetaldehyde tolerance in Saccharomyces cerevisiae involves the pentose phosphate pathway and oleic acid biosynthesis. Yeast 25(11):825-33
Hartman JL 4th  (2007) Buffering of deoxyribonucleotide pool homeostasis by threonine metabolism. Proc Natl Acad Sci U S A 104(28):11700-5
Xia L, et al.  (2007) Identification of genes required for protection from doxorubicin by a genome-wide screen in Saccharomyces cerevisiae. Cancer Res 67(23):11411-8
Dunn CD, et al.  (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26
Freimoser FM, et al.  (2006) Systematic screening of polyphosphate (poly P) levels in yeast mutant cells reveals strong interdependence with primary metabolism. Genome Biol 7(11):R109
Lawrence CL, et al.  (2004) Evidence of a new role for the high-osmolarity glycerol mitogen-activated protein kinase pathway in yeast: regulating adaptation to citric acid stress. Mol Cell Biol 24(8):3307-23
Willingham S, et al.  (2003) Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Science 302(5651):1769-72
Birrell GW, et al.  (2002) Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents. Proc Natl Acad Sci U S A 99(13):8778-83
Desmoucelles C, et al.  (2002) Screening the yeast "disruptome" for mutants affecting resistance to the immunosuppressive drug, mycophenolic acid. J Biol Chem 277(30):27036-44
Birrell GW, et al.  (2001) A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity. Proc Natl Acad Sci U S A 98(22):12608-13
Farfan MJ, et al.  (1996) Effect of gene amplification on threonine production by yeast. Biotechnol Bioeng 49(6):667-74
Schultes NP, et al.  (1990) Saccharomyces cerevisiae homoserine kinase is homologous to prokaryotic homoserine kinases. Gene 96(2):177-80
Hawthorne DC and Mortimer RK  (1960) Chromosome Mapping in Saccharomyces: Centromere-Linked Genes. Genetics 45(8):1085-110