THO2/YNL139C Literature Guide Help

Other names published for THO2: ZRG13, LDB5, RLR1, YNL139C

THO2 - Mutants/Phenotypes (40)

ReferenceOther Genes Addressed
Pena A, et al.  (2012) Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor. EMBO J 31(6):1605-16
Yu TY, et al.  (2012) Depleting Components of the THO Complex Causes Increased Telomere Length by Reducing the Expression of the Telomere-Associated Protein Rif1p. PLoS One 7(3):e33498
Bermejo R, et al.  (2011) The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores. Cell 146(2):233-46
Fell GL, et al.  (2011) Identification of yeast genes involved in k homeostasis: loss of membrane traffic genes affects k uptake. G3 (Bethesda) 1(1):43-56
Gomez-Gonzalez B, et al.  (2011) Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles.LID - 10.1038/emboj.2011.206 [doi] EMBO J ()
Jimeno S, et al.  (2011) New Suppressors of THO Mutations Identify Thp3 (Ypr045c)-Csn12 as a Protein Complex Involved in Transcription Elongation. Mol Cell Biol 31(4):674-685
Konopka CA, et al.  (2011) A yeast model for polyalanine-expansion aggregation and toxicity. Mol Biol Cell 22(12):1971-84
Gaillard H, et al.  (2009) Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair. PLoS Genet 5(2):e1000364
Qu X, et al.  (2009) Assembly of an export-competent mRNP is needed for efficient release of the 3'-end processing complex after polyadenylation. Mol Cell Biol 29(19):5327-38
Skruzny M, et al.  (2009) An endoribonuclease functionally linked to perinuclear mRNP quality control associates with the nuclear pore complexes. PLoS Biol 7(1):e8
Westmoreland TJ, et al.  (2009) Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiae. PLoS ONE 4(6):e5830
Garcia-Rubio M, et al.  (2008) Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity. Mol Genet Genomics 279(2):123-32
Grund SE, et al.  (2008) The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression. J Cell Biol 182(5):897-910
Jimeno S, et al.  (2008) A reduction in RNA polymerase II initiation rate suppresses hyper-recombination and transcription-elongation impairment of THO mutants. Mol Genet Genomics 280(4):327-36
Rougemaille M, et al.  (2008) THO/Sub2p functions to coordinate 3'-end processing with gene-nuclear pore association. Cell 135(2):308-21
Saguez C, et al.  (2008) Nuclear mRNA surveillance in THO/sub2 mutants is triggered by inefficient polyadenylation. Mol Cell 31(1):91-103
Shima J, et al.  (2008) Possible roles of vacuolar H(+)-ATPase and mitochondrial function in tolerance to air-drying stress revealed by genome-wide screening of Saccharomyces cerevisiae deletion strains. Yeast 25(3):179-90
Thomsen R, et al.  (2008) General, rapid, and transcription-dependent fragmentation of nucleolar antigens in S. cerevisiae mRNA export mutants. RNA 14(4):706-16
Gaillard H, et al.  (2007) A new connection of mRNP biogenesis and export with transcription-coupled repair. Nucleic Acids Res 35(12):3893-906
Rollenhagen C, et al.  (2007) Following temperature stress, export of heat shock mRNA occurs efficiently in cells with mutations in genes normally important for mRNA export. Eukaryot Cell 6(3):505-13
Freimoser FM, et al.  (2006) Systematic screening of polyphosphate (poly P) levels in yeast mutant cells reveals strong interdependence with primary metabolism. Genome Biol 7(11):R109
Jimeno S, et al.  (2006) Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants. Mol Cell Biol 26(12):4387-98
Reiner S, et al.  (2006) A genomewide screen reveals a role of mitochondria in anaerobic uptake of sterols in yeast. Mol Biol Cell 17(1):90-103
Rother S, et al.  (2006) Swt1, a novel yeast protein, functions in transcription. J Biol Chem 281(48):36518-25
Voynov V, et al.  (2006) Genes with internal repeats require the THO complex for transcription. Proc Natl Acad Sci U S A 103(39):14423-8
Luna R, et al.  (2005) Interdependence between transcription and mRNP processing and export, and its impact on genetic stability. Mol Cell 18(6):711-22
Corbacho I, et al.  (2004) Identification of low-dye-binding (ldb) mutants of Saccharomyces cerevisiae. FEMS Yeast Res 4(4-5):437-44
Marin A, et al.  (2003) Relationship between G+C content, ORF-length and mRNA concentration in Saccharomyces cerevisiae. Yeast 20(8):703-11
Rondon AG, et al.  (2003) Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation. J Biol Chem 278(40):39037-43
Dimmer KS, et al.  (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53