SRB4/YER022W Literature Guide Help

Other names published for SRB4: MED17, YER022W

SRB4 - Mutants/Phenotypes (31)

ReferenceOther Genes Addressed
Grandin N, et al.  (2012) Genetic and Physical Interactions between Tel2 and the Med15 Mediator Subunit in Saccharomyces cerevisiae. PLoS One 7(1):e30451
Liu Z and Myers LC  (2012) Med5(Nut1) and med17(srb4) are direct targets of mediator histone h4 tail interactions. PLoS One 7(6):e38416
Imasaki T, et al.  (2011) Architecture of the Mediator head module.LID - 10.1038/nature10162 [doi] Nature ()
Lahudkar S, et al.  (2011) The mRNA cap-binding complex stimulates the formation of pre-initiation complex at the promoter via its interaction with Mot1p in vivo. Nucleic Acids Res 39(6):2188-209
Soutourina J, et al.  (2011) Direct interaction of RNA polymerase II and mediator required for transcription in vivo. Science 331(6023):1451-4
Benschop JJ, et al.  (2010) A Consensus of Core Protein Complex Compositions for Saccharomyces cerevisiae. Mol Cell 38(6):916-928
Kaufmann R, et al.  (2010) Infantile Cerebral and Cerebellar Atrophy Is Associated with a Mutation in the MED17 Subunit of the Transcription Preinitiation Mediator Complex. Am J Hum Genet 87(5):667-70
Ansari SA, et al.  (2009) Mediator complex association with constitutively transcribed genes in yeast. Proc Natl Acad Sci U S A 106(39):16734-9
Ohsawa R, et al.  (2009) Epigenetic inheritance of an inducibly nucleosome-depleted promoter and its associated transcriptional state in the apparent absence of transcriptional activators. Epigenetics Chromatin 2(1):11
Young ET, et al.  (2009) Snf1-independent, glucose-resistant transcription of Adr1-dependent genes in a mediator mutant of Saccharomyces cerevisiae. Mol Microbiol 74(2):364-83
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
He Q, et al.  (2008) Mediator Requirement Downstream of Chromatin Remodeling during Transcriptional Activation of CHA1 in Yeast. J Biol Chem 283(9):5276-86
Linder T, et al.  (2008) Two conserved modules of Schizosaccharomyces pombe Mediator regulate distinct cellular pathways. Nucleic Acids Res 36(8):2489-504
Zapater M, et al.  (2007) Selective requirement for SAGA in Hog1-mediated gene expression depending on the severity of the external osmostress conditions. Mol Cell Biol 27(11):3900-10
Linder T, et al.  (2006) The classical srb4-138 mutant allele causes dissociation of yeast Mediator. Biochem Biophys Res Commun 349(3):948-53
Takagi Y and Kornberg RD  (2006) Mediator as a general transcription factor. J Biol Chem 281(1):80-9
Takagi Y, et al.  (2006) Head module control of mediator interactions. Mol Cell 23(3):355-64
Guglielmi B, et al.  (2004) A high resolution protein interaction map of the yeast Mediator complex. Nucleic Acids Res 32(18):5379-91
Estruch F and Cole CN  (2003) An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components. Mol Biol Cell 14(4):1664-76
Sharma VM, et al.  (2003) SWI/SNF-dependent chromatin remodeling of RNR3 requires TAF(II)s and the general transcription machinery. Genes Dev 17(4):502-15
Lee DK, et al.  (1999) Different upstream transcriptional activators have distinct coactivator requirements. Genes Dev 13(22):2934-9
Li XY, et al.  (1999) Enhancement of TBP binding by activators and general transcription factors. Nature 399(6736):605-9
Ranish JA, et al.  (1999) Intermediates in formation and activity of the RNA polymerase II preinitiation complex: holoenzyme recruitment and a postrecruitment role for the TATA box and TFIIB. Genes Dev 13(1):49-63
Holstege FC, et al.  (1998) Dissecting the regulatory circuitry of a eukaryotic genome. Cell 95(5):717-28
Koh SS, et al.  (1998) An activator target in the RNA polymerase II holoenzyme. Mol Cell 1(6):895-904
Lee D and Lis JT  (1998) Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo. Nature 393(6683):389-92
Lee TI, et al.  (1998) Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme. Mol Cell Biol 18(8):4455-62
Lee YC and Kim YJ  (1998) Requirement for a functional interaction between mediator components Med6 and Srb4 in RNA polymerase II transcription. Mol Cell Biol 18(9):5364-70
McNeil JB, et al.  (1998) Activated transcription independent of the RNA polymerase II holoenzyme in budding yeast. Genes Dev 12(16):2510-21
Gadbois EL, et al.  (1997) Functional antagonism between RNA polymerase II holoenzyme and global negative regulator NC2 in vivo. Proc Natl Acad Sci U S A 94(7):3145-50