SLX4/YLR135W Literature Guide Help

Other names published for SLX4: YLR135W

SLX4 - Mutants/Phenotypes (34)

ReferenceOther Genes Addressed
De Muyt A, et al.  (2012) BLM Helicase Ortholog Sgs1 Is a Central Regulator of Meiotic Recombination Intermediate Metabolism. Mol Cell 46(1):43-53
Munoz-Galvan S, et al.  (2012) Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange. Mol Cell Biol 32(9):1592-603
Ward TA, et al.  (2012) Components of a fanconi-like pathway control pso2-independent DNA interstrand crosslink repair in yeast. PLoS Genet 8(8):e1002884
Zakharyevich K, et al.  (2012) Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase. Cell 149(2):334-47
Ashton TM, et al.  (2011) Pathways for Holliday Junction Processing during Homologous Recombination in Saccharomyces cerevisiae. Mol Cell Biol 31(9):1921-33
Leung GP, et al.  (2011) Rtt107 is required for recruitment of the SMC5/6 complex to DNA double strand breaks. J Biol Chem 286(29):26250-7
Reid RJ, et al.  (2011) Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Genome Res 21(3):477-86
Levesque N, et al.  (2010) Loss of H3 K79 trimethylation leads to suppression of Rtt107-dependent DNA damage sensitivity through the translesion synthesis pathway. J Biol Chem 285(45):35113-22
Ohouo PY, et al.  (2010) DNA damage signaling recruits the Rtt107-Slx4 scaffolds via Dpb11 to mediate replication stress response. Mol Cell 39(2):300-6
Toh GW, et al.  (2010) Mec1/Tel1-dependent phosphorylation of Slx4 stimulates Rad1-Rad10-dependent cleavage of non-homologous DNA tails. DNA Repair (Amst) 9(6):718-26
Casper AM, et al.  (2009) Chromosome aberrations resulting from double-strand DNA breaks at a naturally occurring yeast fragile site composed of inverted ty elements are independent of Mre11p and Sae2p. Genetics 183(2):423-39, 1SI-26SI
Mohanty BK, et al.  (2009) Contrasting roles of checkpoint proteins as recombination modulators at Fob1-Ter complexes with or without fork arrest. Eukaryot Cell 8(4):487-95
Munoz IM, et al.  (2009) Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair. Mol Cell 35(1):116-27
Putnam CD, et al.  (2009) Specific pathways prevent duplication-mediated genome rearrangements. Nature 460(7258):984-9
Celic I, et al.  (2008) Histone H3 K56 hyperacetylation perturbs replisomes and causes DNA damage. Genetics 179(4):1769-84
Li F, et al.  (2008) Microarray-based genetic screen defines SAW1, a gene required for Rad1/Rad10-dependent processing of recombination intermediates. Mol Cell 30(3):325-35
Lyndaker AM, et al.  (2008) Mutants Defective in Rad1-Rad10-Slx4 Exhibit a Unique Pattern of Viability During Mating-Type Switching in Saccharomyces cerevisiae. Genetics 179(4):1807-21
Flott S, et al.  (2007) Phosphorylation of Slx4 by Mec1 and Tel1 regulates the single-strand annealing mode of DNA repair in budding yeast. Mol Cell Biol 27(18):6433-45
Klassen R, et al.  (2007) Homologous recombination and the yKu70/80 complex exert opposite roles in resistance against the killer toxin from Pichia acaciae. DNA Repair (Amst) 6(12):1864-75
Liao C, et al.  (2007) Genomic Screening in Vivo Reveals the Role Played by Vacuolar H+ ATPase and Cytosolic Acidification in Sensitivity to DNA-Damaging Agents Such as Cisplatin. Mol Pharmacol 71(2):416-25
Blake D, et al.  (2006) The F-Box Protein Dia2 Overcomes Replication Impedance to Promote Genome Stability in Saccharomyces cerevisiae. Genetics 174(4):1709-27
Butcher RA, et al.  (2006) Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway. Nat Chem Biol 2(2):103-9
Chin JK, et al.  (2006) Esc4/Rtt107 and the control of recombination during replication. DNA Repair (Amst) 5(5):618-28
Roberts TM, et al.  (2006) Slx4 regulates DNA damage checkpoint-dependent phosphorylation of the BRCT domain protein Rtt107/Esc4. Mol Biol Cell 17(1):539-48
Zappulla DC, et al.  (2006) Rtt107/Esc4 binds silent chromatin and DNA repair proteins using different BRCT motifs. BMC Mol Biol 7():40
Zhang C, et al.  (2006) Suppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae. DNA Repair (Amst) 5(3):336-46
Chang M, et al.  (2005) RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex. EMBO J 24(11):2024-33
Deng C, et al.  (2005) Multiple endonucleases function to repair covalent topoisomerase I complexes in Saccharomyces cerevisiae. Genetics 170(2):591-600
Flott S and Rouse J  (2005) Slx4 becomes phosphorylated after DNA damage in a Mec1/Tel1-dependent manner and is required for repair of DNA alkylation damage. Biochem J 391(Pt 2):325-33
Fricke WM and Brill SJ  (2003) Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3. Genes Dev 17(14):1768-78